Obesity
Products for Obesity
- Cat.No. Product Name Information
- GC49008 α-Muricholic Acid-d4 An internal standard for the quantification of α-muricholic acid
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GC40270
(±)5(6)-DiHET
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
- GC45320 1-Stearoyl-3-Oleoyl-rac-glycerol
- GC52071 10-oxo-12(Z)-Octadecenoic Acid A metabolite of linoleic acid and an activator of TRPV1
- GC52398 10-oxo-12(Z)-Octadecenoic Acid ethyl ester An ester form of 10-oxo-12(Z)-octadecenoic acid
- GC52428 10-oxo-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid
- GC41873 10-Thiastearic Acid Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools.
- GC40320 12-PAHSA Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.
- GC18270 22(S)-hydroxy Cholesterol A synthetic oxysterol and LXR modulator
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GC42291
3-Hydroxyisobutyrate (sodium salt)
3-Hydroxyisobutyrate (3-HIB) is an intermediate in the metabolism of the branched-chain amino acid valine that is secreted by skeletal muscle.
- GC49176 5β-Tetrahydrocortisol An endogenous metabolite of cortisol
- GC46757 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) An isomer of linoleic acid
- GC42674 ABD459 ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM).
- GC49393 all-trans-13,14-Dihydroretinol A metabolite of all-trans retinoic acid
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GC40024
Altenusin
Altenusin is a polyphenol fungal metabolite originally isolated from the fungus Alternaria that has diverse biological activities.
- GC42796 Amylin (human) (trifluoroacetate salt) Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety.
- GC52128 AOD-9604
- GC52380 AOD-9604 (acetate) A synthetic lipolytic peptide
- GC46892 ATRA-BA Hybrid A prodrug form of all-trans retinoic acid and butyric acid
- GC49646 Aurothioglucose (hydrate) A TrxR inhibitor
- GC18718 bpV(pic) (potassium hydrate) bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM).
- GC46104 Butyric Acid-d7 An internal standard for the quantification of sodium butyrate
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GC43022
C14 Ceramide (d18:1/14:0)
C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6.
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GC43055
C18:1 Ceramide (d18:1/18:1(9Z))
C18:1 Ceramide is a naturally occurring ceramide.
- GC43068 C20 Sphingomyelin (d18:1/20:0) C20 Sphingomyelin is a naturally occurring sphingolipid.
- GC49433 Capsiate A capsaicin analog with diverse biological activities
- GC40384 CAY10410 CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism.
- GC41601 CAY10591 CAY10591 is a potent activator of Sirt1 and suppresses TNF-α in a dose-dependent manner.
- GC43180 CAY10592 Peroxisome proliferator-activated receptors (PPARs) α, δ, γ are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism.
- GC43215 CCK Octapeptide (non-sulfated), (trifluoroacetate salt) Cholecystokinin (CCK) octapeptide is a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.
- GC47204 D-Fructose-13C6 An internal standard for the quantification of D-fructose
- GC43408 Deoxycholic Acid (sodium salt hydrate) Deoxycholic acid (cholanoic acid) sodium hydrate,a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5.
- GC47187 Deoxycholic Acid-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC49590 Docosahexaenoic Acid 1,2,3,4-13C An internal standard for the quantification of DHA
- GC49324 Enterostatin (human, mouse, rat) (trifluoroacetate salt) A pentapeptide involved in the regulation of food intake
- GC52506 Ghrelin (human) (trifluoroacetate salt) A growth hormone releasing peptide
- GC43754 Ghrelin (rat) (trifluoroacetate salt) Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R).
- GC18387 Glucocerebrosides Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.
- GC43768 Glucocerebrosides (Gaucher's spleen) Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.
- GC52493 Glucosylceramide (bovine buttermilk) A sphingolipid
- GC47408 Glycochenodeoxycholic Acid-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC40912 Glycohyocholic Acid A glycine-conjugated form of hyocholic acid
- GC49006 Glycohyocholic Acid-d4 An internal standard for the quantification of glycohyocholic acid
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GC43778
Glycolithocholic Acid
A glycine-conjugated form of the secondary bile acid lithocholic acid
- GC43779 Glycolithocholic Acid (sodium salt) Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid.
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GC49701
Glycolithocholic Acid 3-sulfate (sodium salt)
A metabolite of glycolithocholic acid
- GC47412 Glycolithocholic Acid-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC43800 GW 9578 Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor found predominantly in the liver that is involved in the regulation of lipid homeostasis.
- GC52251 Imidacloprid Impurity 1 A potential impurity in commercial preparations of imidacloprid
- GC47464 Isodeoxycholic Acid A bile acid
- GC47466 Isolithocholic Acid A bile acid
- GC43929 JMV3002 Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis.
- GC52497 Lactosylceramide (porcine RBC) A sphingolipid
- GC40142 Lactosylceramides (bovine buttermilk) Lactosylceramide (LacCer) is an endogenous bioactive sphingolipid.
- GC52331 Lactoyl Phenylalanine A secondary metabolite
- GC46028 Malabaricone C A diarylnonanoid with diverse biological activities
- GC46168 MBX-8025 (sodium salt) A PPARδ agonist
- GC44441 N-Oleoyl Leucine N-Oleoyl leucine is an N-acyl amide generated by PM20D1 that uncouples mitochondrial respiration independent of uncoupling protein 1 (UCP1) in vitro.
- GC47768 Neuromedin U-25 (human) (trifluoroacetate salt) A neuropeptide with diverse roles
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GC52214
Nicotinamide riboside-d4 (triflate)
An internal standard for the quantification of nicotinamide riboside
- GC44481 O-7460 In humans, two forms of diacylglycerol lipase, DAGLα and DAGLβ, generate the endocannabinoid 2-arachidonoyl glycerol by attacking DAG at the sn-1 position.
- GC48328 Obestatin (human) (trifluoroacetate salt) A peptide hormone
- GC44484 Obestatin (rat) (trifluoroacetate salt) Obestatin is a 23-amino acid peptide hormone that is formed by cleavage of the ghrelin and obestatin prepropeptide.
- GC47819 Oleoyl Ethanolamide-d2 An internal standard for the quantification of oleoyl ethanolamide
- GC47820 Oleoyl Ethanolamide-d4 An internal standard for the quantification of oleoyl ethanolamide
- GC49815 Oleuropein aglycone A polyphenol with diverse biological activities
- GC52453 Orexin A (17-33) (human, mouse, rat, bovine) (trifluoroacetate salt) A peptide orexin receptor 1 agonist
- GC52507 Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt) A hypothalamic neuropeptide
- GC44516 Orlistat Degradation Product (sodium salt) Orlistat degradation product is a degradation product of the digestive lipase inhibitor orlistat.
- GC49236 Orlistat-d3 An internal standard for the quantification of orlistat
- GC44529 P053 P053 is an inhibitor of ceramide synthase 1 (CerS1; IC50s = 0.54 and 0.46 μM for human and mouse CerS1, respectively).
- GC52502 Peptide YY (3-36) (trifluoroacetate salt) A satiety hormone
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GC44598
Peptide YY (human) (trifluoroacetate salt)
Peptide YY (PYY) is a 36-amino acid peptide and anorectic gut hormone agonist for the neuropeptide Y receptors Y1, Y2, Y5, and Y6 with EC50 values of 0.7, 0.58, 1, and 0.8 nM, respectively, for supression of forskolin-induced cAMP accumulation.
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GC41647
Pinolenic Acid
Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils.
- GC40788 Pinolenic Acid ethyl ester Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils.
- GC40713 Pinolenic Acid methyl ester Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils.
- GC18762 Remogliflozin A Remogliflozin A is a potent and selective inhibitor of SGLT2 (sodium-glucose cotransporter 2) with Kis of 12.4 and 26 nM for human and rat SGLT2, respectively.
- GC44811 Remogliflozin etabonate Remogliflozin etabonate is a prodrug form of the sodium-glucose transporter 2 (SGLT2) inhibitor remogliflozin A.
- GC48054 Rimonabant-d10 An internal standard for the quantification of rimonabant
- GC49881 Setmelanotide (trifluoroacetate salt) A peptide agonist of MC4R
- GC45567 SR 1903
- GC49844 Stercobilin (hydrochloride) A fecal pigment and metabolite of bilirubin
- GC44954 Stevioside (hydrate) Stevioside is a natural non-caloric sweetener.
- GC48112 Sucralose-d6 An internal standard for the quantification of sucralose
- GC49012 Tauro-β-muricholic Acid-d4 (sodium salt) An internal standard for the quantification of tauro-β-muricholic acid
- GC52135 Tesofensine Tesofensine (NS-2330) is a triple monoamine reuptake inhibitor inducing a potent inhibition of the re-uptake process in the synaptic cleft of the neurotransmitters dopamine (DA; IC50=6.5 nM), norepinephrine (NE;IC50=1.7 nM), and serotonin (5-HT;IC50=11 nM), and with potentials as an anti-obesity agent.
- GC49884 Trigonelline-d3 (chloride) An internal standard for the quantification of trigonelline
- GC45164 WWL229 Mouse carboxylesterase 3 (Ces3, also named Ces1d) mediates triglyceride hydrolysis in white adipose tissue, liberating free fatty acids into circulation.
- GC52388 [D-Lys3]-GHRP-6 (trifluoroacetate salt) An antagonist of GHS-R1a