ATP citrate lyase
ACLY (ATP citrate lyase) catalyzes the synthesis of acetyl-CoA from citrate. It is a cytosolic enzyme that involved in fetal growth/development, tumor cell growth/survival and metabolic disorder etc.
Products for ATP citrate lyase
- Cat.No. Product Name Information
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GC48923
(±)-Hydroxycitric Acid
HCA
A hydroxy derivative of citric acid
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GC71452
(-)-Hydroxycitric acid
(-)-Hydroxycitric acid (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia.
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GC63570
(-)-Hydroxycitric acid lactone
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement.
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GC31632
2-Furoic acid (Furan-2-carboxylic acid)
2-Furoic acid (Furan-2-carboxylic acid) (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation.
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GC10884
BMS-303141
BMS-303141 is a highly potent and cell-permeable ATP-citrate lyase (ACL) inhibitor with an IC50 value of 0.13μM.
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GC33760
ETC-1002 (ESP-55016)
Bempedoic Acid, ESP-55016
ETC-1002 (ESP-55016) (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor.
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GC60919
Hydroxycitric acid tripotassium hydrate
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) is the major active ingredient of Garcinia cambogia.
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GC38932
NDI-091143
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate.
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GC16952
SB 204990
ATP citrate lyase (ACLY) inhibitor
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