Glucosidase
Glucosidases are glycoside hydrolase enzymes.
α-glucosidase is a glucosidase located in the brush border of the small intestine that acts upon α(1→4) bonds. α-Glucosidase inhibitor is a new type of antidiabetics. By reducing the postprandial blood sugar concentration, it can effectively control the blood sugar levels, thereby reducing the occurrence of diabetic complications.
β-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues in β-D-glucosides and oligosaccharides, with release of glucose. β-Glucosidase has attracted substantial attention in the scientific community because of its pivotal role in cellulose degradation, glycoside transformation and many other industrial processes. β-glucosidases catalyze the final step of cellulose hydrolysis and are essential in cellulose degradation.
Products for Glucosidase
- Cat.No. Product Name Information
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GC70181
α-Glucosidase-IN-22
Alpha-glucosidase-IN-22 (compound 7i) is a benzimidazole, an effective inhibitor of alpha-glucosidase with an IC50 of 0.64 μM. Alpha-glucosidase-IN-22 is an effective anti-diabetic active molecule with potential for use in type 2 diabetes (T2DM) research.
- GC62551 β-Hydroxypropiovanillone β-Hydroxypropiovanillone, a natural compound, shows significant concentration-dependent inhibitory effects on α-glucosidase with an IC50 of 257.8 μg/mL.
- GC39795 (+)-Afzelechin (+)-Afzelechin, isolated from rhizomes of Bergenia ligulata, is an alpha-glucosidase activity inhibitor with an ID50 (50% inhibition dose) value of 0.13 mM.
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GC68525
(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid
(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid is a saponin that can be isolated from Rubus ellipticus var. obcordatus. It inhibits α-Glucosidase with an IC50 of 1.68 mM.
- GN10317 1-Deoxynojirimycin
- GC41992 1-Deoxynojirimycin (hydrochloride) 1-Deoxynojirimycin (1-dNM) (hydrochloride), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II.
- GC30277 4',5-Dihydroxyflavone 4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase.
- GC35553 Brevifolincarboxylic acid Brevifolincarboxylic acid is extracted from Polygonum capitatum, has inhibitory effect on the aryl hydrocarbon receptor (AhR).
- GC39233 Butyl isobutyl phthalate Butyl isobutyl phthalate is isolated from the rhizoid of Laminaria japonica.
- GC38279 Cedryl acetate Cedryl acetate is a tricyclic sesquiterpene isolated from the plant Psidium caudatum.
- GC31580 Cefetrizole Ceftezole is an α-Glucosidase inhibitor with an IC50 and a Ki of 2.1 μM and 0.578 μM, respectively.
- GC32191 Celgosivir (MBI 3253) Celgosivir (MBI 3253) (MBI 3253; MDL 28574; MX3253) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.
- GC32074 Celgosivir hydrochloride (MBI 3253 (hydrochloride)) Celgosivir hydrochloride (MBI 3253 (hydrochloride)) (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.
- GC60706 Chrysophanol triglucoside Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia, inhibits protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase with IC50s of 80.17 and 197.06 ?M, respectively.
- GC18058 Conduritol B epoxide β-glucosidase inhibitor
- GC60802 Eleutherol Eleutherol is a naphthalene isolated from E.
- GC62984 Ganoderic acid Y Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase.
- GC64202 Ganoderlactone D Ganoderlactone D shows inhibitory effects of yeast α-Glucosidase with IC50 values of 41.7 μM.
- GC38046 Gitogenin Gitogenin is a natural steroid isolated from the whole plant of Tribulus longipetalus.
- GC36165 Glycyrrhisoflavone Glycyrrhisoflavone, an active prenylflavonoid, inhibits α-glucosidase.
- GC36347 Isotanshinone I Isotanshinone I has inhibitory activity against α-glucosidase and formation of AGE, with IC50s of 1.13 μM and 0.432 μM for α-glucosidase and AGE, respectively.
- GC36375 Kaempferol 3-O-gentiobioside Kaempferol 3-O-gentiobioside is a flavonoid isolated from C.
- GC64519 Kaempferol-3,7-di-O-β-glucoside Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase.
- GC61635 Kaempferol-7-O-rhamnoside Kaempferol-7-O-rhamnoside, isolated from Chimonanthus nitens Oliv.
- GN10551 Licochalcone C
- GC64507 ML198 ML198 is a glucocerebrosidase (GCase) modulator with an EC50 of 0.4 μM.
- GC63442 N-Caffeoyl O-methyltyramine N-Caffeoyl O-methyltyramine is a class of alkaloid isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase (IC50 of 103.58 μM).
- GC30637 N-Methylmoranoline (MOR 14) N-Methylmoranoline (MOR 14) (MOR 14) is an α-glucosidase inhibitor.
- GC61697 Naringinase Naringinase, a hydrolytic enzymatic complex, possesses the activity of both α-L-rhamnosidase and β-D-glucosidase.
- GC63099 NCGC00092410 NCGC00092410 is a potent, selective, and nonsugar glucocerebrosidase (GC) inhibitor, with an IC50 of 31 nM.
- GC67983 Norathyriol
- GN10114 Oroxin A
- GC65271 p-Hydroxyphenethyl trans-ferulate p-Hydroxyphenethyl trans-ferulate has anti-hyperglycemic(yeast α-glucosidase,IC50 19.24 ± 1.73 ?mol L-1), antioxidant, and anti-inflammatory activities.
- GC38995 Panasenoside Panasenoside is a flavonoid isolated from Lilium pumilum D.
- GN10011 Rebaudioside A
- GC61242 Resveratroloside Resveratroloside is a competitive inhibitior of α-glucosidase with an IC50 of 22.9 μM.
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GC34835
Terphenyllin
A fungal metabolite with antibacterial properties
- GC18007 Voglibose α-glucosidases inhibitor