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Home >> Signaling Pathways >> Others >> MDR multidrug resistance

MDR multidrug resistance

MDR (multidrug resistance) is a property that first identified in tumor cell, hat the resistance of tumor cell is to a variety of chemotherapy agent due to active efflux via transporter proteins.

Products for  MDR multidrug resistance

  1. Cat.No. Product Name Information
  2. GC45246 (-)-Chaetominine (-)-Chaetominine is a cytotoxic alkaloid originally isolated from Chaetomium sp. (-)-Chaetominine Chemical Structure
  3. GC41865 10'-Desmethoxystreptonigrin 10'-Desmethoxystreptonigrin is an antibiotic originally isolated from Streptomyces and a derivative of the antibiotic streptonigrin. 10'-Desmethoxystreptonigrin Chemical Structure
  4. GC45324 2,5-dimethyl Celecoxib   2,5-dimethyl Celecoxib Chemical Structure
  5. GC42616 7-oxo Staurosporine

    7-oxo Staurosporine is an antibiotic originally isolated from S.

     7-oxo Staurosporine Chemical Structure
  6. GC49275 8-Oxycoptisine 8-Oxycoptisine is a natural protoberberine alkaloid with anti-cancer activity. 8-Oxycoptisine Chemical Structure
  7. GC46809 Afatinib-d6 An internal standard for the quantification of afatinib Afatinib-d6 Chemical Structure
  8. GC42806 Andrastin A Andrastin A is a meroterpenoid farnesyltransferase inhibitor. Andrastin A Chemical Structure
  9. GC43004 C10 Ceramide (d18:1/10:0)

    C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase.

     C10 Ceramide (d18:1/10:0) Chemical Structure
  10. GC43060 C2 Adamantanyl Globotriaosylceramide (d18:1/2:0) C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. C2 Adamantanyl Globotriaosylceramide (d18:1/2:0) Chemical Structure
  11. GC45395 Cabazitaxel-d9 Cabazitaxel-d9 is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel-d9 Chemical Structure
  12. GC45679 Carubicin An anthracycline with anticancer activity Carubicin Chemical Structure
  13. GC40795 CAY10503 CAY10503 is a proapoptotic, antiproliferative compound that is able to arrest cell cycle progression in the G0-G1 phase. CAY10503 Chemical Structure
  14. GC18901 CAY10647 CAY10647 is an aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg). CAY10647 Chemical Structure
  15. GC45792 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) An inducer of ferroptosis Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) Chemical Structure
  16. GC46004 Evoxanthine An alkaloid Evoxanthine Chemical Structure
  17. GC49106 Gentisein A xanthone with diverse biological activities Gentisein Chemical Structure
  18. GC47409 Glycocholic Acid-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Glycocholic Acid-d4 Chemical Structure
  19. GC49670 Indium (III) thiosemicarbazone 5b An anticancer agent Indium (III) thiosemicarbazone 5b Chemical Structure
  20. GC44129 MC 70 A P-glycoprotein inhibitor MC 70 Chemical Structure
  21. GC48479 Migrastatin A fungal metabolite with antimuscarinic and anticancer activities Migrastatin Chemical Structure
  22. GC44195 Milbemycin A4 oxime Milbemycin A4 oxime is a derivative of milbemycin A4 and a component of milbemycin oxime, compounds that both have insecticidal and nematocidal activity. Milbemycin A4 oxime Chemical Structure
  23. GC41564 MPT0B014 An inhibitor of tubulin polymerization MPT0B014 Chemical Structure
  24. GC45784 ONT-093 A P-glycoprotein inhibitor ONT-093 Chemical Structure
  25. GC49251 Oxaliplatin-d10 An internal standard for the quantification of oxaliplatin Oxaliplatin-d10 Chemical Structure
  26. GC44613 PF-6274484 PF-6274484 is an inhibitor of the EGF receptor (EGFR; IC50s = 0.18 and 0.14 nM for wild-type EGFR and inhibitor-resistant EGFRL858R/T790M, respectively). PF-6274484 Chemical Structure
  27. GC44615 PGP-4008 PGP-4008 is a selective inhibitor of P-glycoprotein (P-gp) that does not affect the activity of multidrug resistance-related protein 1 (MRP1). PGP-4008 Chemical Structure
  28. GC41629 Piperafizine A Piperafizine A is a natural methylated diketopiperazine first isolated from an actinomycete, Streptoverticillium. Piperafizine A Chemical Structure
  29. GC52455 Pixantrone-d8 (maleate) An internal standard for the quantification of pixantrone Pixantrone-d8 (maleate) Chemical Structure
  30. GC52104 Ponatinib (hydrochloride) An inhibitor of native and mutant Bcr-Abl Ponatinib (hydrochloride) Chemical Structure
  31. GC17403 Pyronaridine Tetraphosphate

    An antimalarial agent

     Pyronaridine Tetraphosphate Chemical Structure
  32. GC44821 Reversin 121 Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. Reversin 121 Chemical Structure
  33. GC45688 STX140 An estrogen sulfamate STX140 Chemical Structure
  34. GC48119 Suprafenacine An inhibitor of tubulin polymerization with anticancer activity Suprafenacine Chemical Structure
  35. GC48219 Ulipristal Acetate-d6 An internal standard for the quantification of ulipristal acetate Ulipristal Acetate-d6 Chemical Structure
  36. GC49308 Ungeremine A betaine-type alkaloid with diverse biological activities Ungeremine Chemical Structure

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