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Home >> Signaling Pathways >> Others >> Renin

Renin

Renin is an asparyl protease that cleaves angiotensinogen into angiotension I in the plasma. It functions as a regulator of blood pressure and sodium homeostasis.

Products for  Renin

  1. Cat.No. Product Name Information
  2. GC31621 ACT 178882 ACT 178882 is a new Renin inhibitor with an IC50 of 1.4 nM. ACT 178882 Chemical Structure
  3. GC15451 Aliskiren Aliskiren Chemical Structure
  4. GC35285 Aliskiren D6 Hydrochloride Aliskiren D6 Hydrochloride (CGP 60536 D6 Hydrochloride) is is deuterium labeled Aliskiren, which is a direct renin inhibitor with IC50 of 1.5 nM. Aliskiren D6 Hydrochloride Chemical Structure
  5. GC13223 Aliskiren Hemifumarate

    CGP 60536, SPP 100

     renin inhibitor Aliskiren Hemifumarate Chemical Structure
  6. GC35380 Araloside A

    Chikusetsusaponin 4, Chikusetsusaponin IV, Oleanoside E

     Araloside A (Chikusetsusaponin IV) is a component of Panax japonicus, with low-renin-inhibitory activity, with an IC50 of 77.4 μM. Araloside A Chemical Structure
  7. GC30633 Handle region peptide, rat Handle region peptide, rat is a prorenin receptor antagonist, suppresses the progression of diabetic nephropathy and has anti-inflammatory in the eye. Handle region peptide, rat Chemical Structure
  8. GC69938 SPH3127

    SPH3127 (DRI 18) is a novel, highly effective, and orally active direct renin inhibitor (recombinant human-renin IC50=0.4 nM, human plasma renin activity IC50=0.45 nM). SPH3127 has antihypertensive effects and can be used in the research of hypertension.

     SPH3127 Chemical Structure
  9. GC16809 VTP-27999 A renin inhibitor VTP-27999 Chemical Structure
  10. GC37925 VTP-27999 Hydrochloride VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases. VTP-27999 Hydrochloride Chemical Structure
  11. GC37926 VTP-27999 TFA A renin inhibitor VTP-27999 TFA Chemical Structure

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