Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

    image loader

    Adding item(s) to cart......

Home >> Signaling Pathways >> Others >> SPHK

SPHK

SPHK (sphingosine kinase) is a conserved lipid kinase that catalyzes formation S1P (sphingosine-1-phosphate) from the precursor sphingolipid sphingosine.

Products for  SPHK

  1. Cat.No. Product Name Information
  2. GN10444 12-O-tetradecanoyl phorbol-13-acetate

    A PKC activator

     12-O-tetradecanoyl phorbol-13-acetate Chemical Structure
  3. GC10154 ABC294640 ABC294640 (ABC294640) is a selective, competitive sphingosine kinase 2 (SK2) inhibitor with Ki of 9.8 μM. ABC294640 Chemical Structure
  4. GC12581 K145 SphK2 inhibitor K145 Chemical Structure
  5. GC36372 K145 hydrochloride A selective SPHK2 inhibitor K145 hydrochloride Chemical Structure
  6. GC19501 MHP

    MHP is an activator of sphingosine kinase (SPHK1)

     MHP Chemical Structure
  7. GC33016 MP-A08 An inhibitor of SK1 and SK2 MP-A08 Chemical Structure
  8. GC32107 Peretinoin (NIK333) Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as retinoid X receptor (RXR) and retinoic acid receptor (RAR). Peretinoin (NIK333) Chemical Structure
  9. GC50253 PF 543 hydrochloride Potent and selective SphK1 inhibitor PF 543 hydrochloride Chemical Structure
  10. GC11917 PF-543

    PF-543 is a novel cell-permeable sphingosine kinase (SphK1) inhibitor with an IC50 value of 3.6 nM and a Ki value of 3.6 nM.

     PF-543 Chemical Structure
  11. GC16352 PF-543 Citrate PF-543 Citrate Chemical Structure
  12. GC61597 SK1-I SK1-I (BML-258), an analog of sphingosine, is an isozyme-specific competitive SPHK1 inhibitor with a Ki value of 10 ?M. SK1-I shows no activity at SPHK1 PKCα, PKCδ, PKA, AKT1, ERK1, EGFR, CDK2, IKKβ or CamK2β. SK1-I enhances autophagy and has antitumor activity. SK1-I Chemical Structure
  13. GC33836 SK1-IN-1 SK1-IN-1 is a potent sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 58 nM. SK1-IN-1 Chemical Structure
  14. GC44896 SKI 178 SKI 178 is an inhibitor of sphingosine kinase 1 (SPHK1) and SPHK2. SKI 178 Chemical Structure
  15. GC16701 SKI II Sphingosine kinase(SK) inhibitor SKI II Chemical Structure
  16. GC60339 SKI V SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity. SKI V Chemical Structure
  17. GC66011 SKI-I SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK), with an IC50 of 1.2 μM for ST-hSK. SKI-I also inhibits hERK2 (IC50=11 μM). SKI-I induces apoptosis in tumor cell lines. SKI-I Chemical Structure

16 Item(s)

per page

Set Descending Direction