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Home >> Signaling Pathways >> Others >> Transcription Factors

Transcription Factors

Products for  Transcription Factors

  1. Cat.No. Product Name Information
  2. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  3. GC52010 (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid An oxylipin gut microbiota metabolite (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid Chemical Structure
  4. GC46347 (S)-(+)-Methoprene An insect growth regulator and Met agonist (S)-(+)-Methoprene Chemical Structure
  5. GC52026 10-oxo-12(Z),15(Z)-Octadecadienoic Acid An oxylipin gut microbiota metabolite 10-oxo-12(Z),15(Z)-Octadecadienoic Acid Chemical Structure
  6. GC42075 2,4-Pyridinedicarboxylic Acid (hydrate) 2,4-Pyridinedicarboxylic Acid (2,4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG, also known as α-ketoglutarate) and chelates zinc, thus affecting a range of enzymes. 2,4-Pyridinedicarboxylic Acid (hydrate) Chemical Structure
  7. GC46503 2-(1,8-Naphthyridin-2-yl)phenol 2-(1,8-Naphthyridin-2-yl)phenol is a selective enhancer of STAT1 transcription. 2-(1,8-Naphthyridin-2-yl)phenol can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells. 2-(1,8-Naphthyridin-2-yl)phenol Chemical Structure
  8. GC46553 2-Nonylquinolin-4(1H)-one A quinolone alkaloid with diverse biological activities 2-Nonylquinolin-4(1H)-one Chemical Structure
  9. GC52446 2-Nonylquinolin-4(1H)-one-d4 An internal standard for the quantification of 2-nonylquinolin-4(1H)-one 2-Nonylquinolin-4(1H)-one-d4 Chemical Structure
  10. GC52129 3-Amino-5-hydroxybenzoic Acid 3-Amino-5-hydroxybenzoic Acid Chemical Structure
  11. GC18194 4-Epidoxycycline 4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline . 4-Epidoxycycline Chemical Structure
  12. GC48824 4-hydroxy Estrone A metabolite of estrone 4-hydroxy Estrone Chemical Structure
  13. GC46673 4-octynyl Itaconate 4-octynyl Itaconate (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. 4-octynyl Itaconate Chemical Structure
  14. GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7 Chemical Structure
  15. GC45960 9c(i472) 9c(i472) is a potent inhibitor of 15-LOX-1 (15-lipoxygenase-1) with an IC50 value of 0.19 μM. 9c(i472) Chemical Structure
  16. GC42743 AEM1 Cancer cell survival appears partly dependent on antioxidative enzymes, whose expression is regulated by the Keap1-Nrf2 pathway, to quench potentially toxic reactive oxygen species generated by their metastatic transformation. AEM1 Chemical Structure
  17. GC16227 Anhydrotetracycline (hydrochloride) powerful effector in both the tetracycline repressor (TetR) and reverse TetR (revTetR) systems Anhydrotetracycline (hydrochloride) Chemical Structure
  18. GC46862 Apigenin-d5 An internal standard for the quantification of apigenin Apigenin-d5 Chemical Structure
  19. GC42880 Avenanthramide-C methyl ester Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Avenanthramide-C methyl ester Chemical Structure
  20. GC42925 Berteroin Berteroin is a sulforaphane analog found in cruciferous vegetables including Chinese cabbage, rucola salad leaves, and mustard oil. Berteroin Chemical Structure
  21. GC13231 BI 6015 HNF4α antagonist BI 6015 Chemical Structure
  22. GC42953 BMS 345541 (trifluoroacetate salt) BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM). BMS 345541 (trifluoroacetate salt) Chemical Structure
  23. GC10233 BRD 7552 PDX1 inducer BRD 7552 Chemical Structure
  24. GC42975 BRD32048 ETS variant 1 (ETV1) is a transcription factor oncogene implicated in several cancers where it has been altered by chromosomal translocation, gene amplification, or lineage dysregulation. BRD32048 Chemical Structure
  25. GC42997 Butyrolactone I A secondary metabolite from A Butyrolactone I Chemical Structure
  26. GC43110 C8 Galactosylceramide (d18:1/8:0) C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. C8 Galactosylceramide (d18:1/8:0) Chemical Structure
  27. GC43176 CAY10575 CAY10575 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM. CAY10575 Chemical Structure
  28. GC43189 CAY10681 Inactivation of the tumor suppressor p53 commonly coincides with increased signaling through NF-κB in cancer. CAY10681 Chemical Structure
  29. GC43190 CAY10682 (±)-Nutlin-3 blocks the interaction of p53 with its negative regulator Mdm2 (IC50 = 90 nM), inducing the expression of p53-regulated genes and blocking the growth of tumor xenografts in vivo. CAY10682 Chemical Structure
  30. GC15474 CBFβ Inhibitor CBFβ inhibitor CBFβ Inhibitor Chemical Structure
  31. GC14266 CCG 203971

    Antifibrotic agent

     CCG 203971 Chemical Structure
  32. GC43212 CCG-232601 CCG-232601 is an inhibitor of the Rho/MRTF/SRF transcriptional pathway and a derivative of CCG-203971. CCG-232601 Chemical Structure
  33. GC48982 CD532 An inhibitor of Aurora A kinase activity and the Aurora A-N-Myc protein-protein interaction CD532 Chemical Structure
  34. GC18392 Cellocidin Cellocidin is an antibiotic originally isolated from S. Cellocidin Chemical Structure
  35. GC52081 Chamazulene

    Chamazulene is a terpene that has been found in chamomile (M. recutita) flowers and has anti-inflammatory and antioxidant activities.

     Chamazulene Chemical Structure
  36. GC14685 CID 5951923 inhibitor of Krüppel-like factor 5 (KLF5) transcription factor CID 5951923 Chemical Structure
  37. GC43368 D,L-1′-Acetoxychavicol Acetate D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants. D,L-1′-Acetoxychavicol Acetate Chemical Structure
  38. GC52194 Dimethylamino Parthenolide Dimethylamino Parthenolide Chemical Structure
  39. GC43493 DL-Sulforaphane N-acetyl-L-cysteine Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress. DL-Sulforaphane N-acetyl-L-cysteine Chemical Structure
  40. GC46148 Filgotinib-d4 An internal standard for the quantification of filgotinib Filgotinib-d4 Chemical Structure
  41. GC49344 Fisetin-d5 An internal standard for the quantification of fisetin Fisetin-d5 Chemical Structure
  42. GC18652 FQI 1 An inhibitor of Late SV40 Factor FQI 1 Chemical Structure
  43. GC18796 Herbicidin A Herbicidin A is an adenine nucleoside antibiotic originally isolated from S. Herbicidin A Chemical Structure
  44. GC47435 HPI-1 (hydrate) A Hedgehog pathway inhibitor HPI-1 (hydrate) Chemical Structure
  45. GC49742 Hsf1 Monoclonal Antibody (Clone 10H8) For immunochemical analysis of Hsf1 Hsf1 Monoclonal Antibody (Clone 10H8) Chemical Structure
  46. GC43893 iKIX1 An inhibitor of Mediator/Pdr1 interactions iKIX1 Chemical Structure
  47. GC43894 IKK2 Inhibitor VI

    Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling.

     IKK2 Inhibitor VI Chemical Structure
  48. GC47456 Indole-3-pyruvic Acid Indole-3-pyruvic Acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic Acid Chemical Structure
  49. GC49290 Indoxyl Sulfate-d5 (potassium salt) An internal standard for the quantification of indoxyl sulfate Indoxyl Sulfate-d5 (potassium salt) Chemical Structure
  50. GC48618 Isonanangenine B A drimane sesquiterpene lactone Isonanangenine B Chemical Structure
  51. GC11197 KL 001 cryptochrome protein (CRY) stabilizer KL 001 Chemical Structure
  52. GC52283 L-Cysteine-15N-d3 An internal standard for the quantification of L-cysteine L-Cysteine-15N-d3 Chemical Structure
  53. GC48907 Metaxalone-d6 An internal standard for the quantification of metaxalone Metaxalone-d6 Chemical Structure
  54. GC49241 Methyl Diethyldithiocarbamate An active metabolite of disulfiram Methyl Diethyldithiocarbamate Chemical Structure
  55. GC44216 ML-180 ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. ML-180 Chemical Structure
  56. GC11307 ML-264 Krüppel-like factor 5 (KLF5) inhibitor ML-264 Chemical Structure
  57. GC14832 N-3-oxo-octanoyl-L-Homoserine lactone A bacterial quorum sensing signal molecule N-3-oxo-octanoyl-L-Homoserine lactone Chemical Structure
  58. GC44459 N-pentadecanoyl-L-Homoserine lactone Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. N-pentadecanoyl-L-Homoserine lactone Chemical Structure
  59. GC44388 NF-κB Control NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. NF-κB Control Chemical Structure
  60. GC48985 NF-κB Inhibitor (trifluoroacetate salt) A cell-permeable peptide that blocks nuclear import of NF-κB NF-κB Inhibitor (trifluoroacetate salt) Chemical Structure
  61. GC12499 O4I1

    potent Oct3/4 inducer

     O4I1 Chemical Structure
  62. GC10151 OAC1 Oct4 activator OAC1 Chemical Structure
  63. GC17327 OAC2 Oct4 activator OAC2 Chemical Structure
  64. GC10724 OAC3 Oct4 activator OAC3 Chemical Structure
  65. GC44652 PK7242 (maleate) The protein p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further proliferation of the stressed cell by promoting cell cycle arrest or apoptosis. PK7242 (maleate) Chemical Structure
  66. GC49860 Pyropheophorbide a methyl ester Pyropheophorbide a methyl ester (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Pyropheophorbide a methyl ester has photodynamic activity and can induce apoptosis and inhibit tumor growth. Pyropheophorbide a methyl ester Chemical Structure
  67. GC50256 RG 102240

    Gene switch ligand for use in inducible gene expression systems

     RG 102240 Chemical Structure
  68. GC12727 Ro 5-3335 Core binding factor (CBF) inhibitor Ro 5-3335 Chemical Structure
  69. GC18624 Roslin-2 Roslin-2 (Benzylhexamethylenetetramine bromide) is a p53 reactivator with anticancer effects. Roslin-2 binds FAK, disrupts the binding of FAK and p53. Roslin-2 Chemical Structure
  70. GC44888 SI-2

    SI-2 is an inhibitor of steroid receptor coactivator 3 (SRC-3).

     SI-2 Chemical Structure
  71. GC49002 Sinigrin (hydrate) A glucosinolate with diverse biological activities Sinigrin (hydrate) Chemical Structure
  72. GC49049 SMU127 An agonist of TLR1/2 SMU127 Chemical Structure
  73. GC44943 sPLA2 Inhibitor sPLA2 Inhibitor, a D-tyrosine derivative, is an orally active, potent secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 29 nM for human nonpancreatic secretory PLA2 isoform IIa (hnpsPLA2-IIa). sPLA2 Inhibitor Chemical Structure
  74. GC48098 SR 12343 An IKKβ NBD mimetic SR 12343 Chemical Structure
  75. GC48099 SR 12460 An IKKβ NBD mimetic SR 12460 Chemical Structure
  76. GC17839 Stauprimide Small molecule that primes embryonic stem cells (ESCs) for differentiation Stauprimide Chemical Structure
  77. GC16165 T-5224 T-5224 is a non-peptidic small molecule AP-1 inhibitor T-5224 Chemical Structure
  78. GC44984 TAF 10 Peptide TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity. TAF 10 Peptide Chemical Structure
  79. GC49692 Tofacitinib-d3 (citrate) An internal standard for the quantification of tofacitinib Tofacitinib-d3 (citrate) Chemical Structure
  80. GC45965 Tolfenamic Acid-d4 An internal standard for the quantification of tolfenamic acid Tolfenamic Acid-d4 Chemical Structure
  81. GC48195 trans-trismethoxy Resveratrol-d4 An internal standard for the quantification of trans-trismethoxy resveratrol trans-trismethoxy Resveratrol-d4 Chemical Structure
  82. GC48202 Treprostinil (diethanolamine salt) Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (diethanolamine salt) Chemical Structure
  83. GC49835 Tumulosic Acid Tumulosic Acid, a triterpenoid, inhibits KLK5 protease activity (IC50= 14.84 μM). Tumulosic Acid Chemical Structure
  84. GC52180 WAY-169916 WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity. WAY-169916 Chemical Structure

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