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Home >> Signaling Pathways >> Others >> Transcription Factors

Transcription Factors

Products for  Transcription Factors

  1. Cat.No. Product Name Information
  2. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    α-Melanocyte-stimulating Hormone, Ac-SYSMEHFRWGKPV-NH2

     α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  3. GC52010 (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid

    αHYA, (±)-10-hydroxy-12(Z),15(Z)-ODE

     An oxylipin gut microbiota metabolite (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid Chemical Structure
  4. GC40440 (±)8(9)-EET

    (±)8,9EpETrE

     (±)8(9)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid. (±)8(9)-EET Chemical Structure
  5. GC40838 (±)8(9)-EET methyl ester

    (±)8,9EpETrE methyl ester

     (±)8(9)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. (±)8(9)-EET methyl ester Chemical Structure
  6. GC46264 (±)8(9)-EET-d11

    (±)8,9-EET-d11, (±)8,9-EpETrE-d11

     A neuropeptide with diverse biological activities (±)8(9)-EET-d11 Chemical Structure
  7. GC45921 (±)8(9)-EET-d11 methyl ester

    (±)8,9-EpETrE-d11 methyl ester

     A neuropeptide with diverse biological activities (±)8(9)-EET-d11 methyl ester Chemical Structure
  8. GC18773 (Rac)-Benpyrine A racemate of Benpyrine, is a potent and orally active TNF-α inhibitor (Rac)-Benpyrine Chemical Structure
  9. GC46347 (S)-(+)-Methoprene

    Altosid, d-Methoprene, ZR 2458

     An insect growth regulator and Met agonist (S)-(+)-Methoprene Chemical Structure
  10. GC52026 10-oxo-12(Z),15(Z)-Octadecadienoic Acid

    10-oxo-12(Z),15(Z)-18:2, 10-oxo-12(Z),15(Z)-ODE

     An oxylipin gut microbiota metabolite 10-oxo-12(Z),15(Z)-Octadecadienoic Acid Chemical Structure
  11. GC42075 2,4-Pyridinedicarboxylic Acid (hydrate)

    2,4-Dicarboxylpyridine, 2,4-PDCA

     2,4-Pyridinedicarboxylic Acid (2,4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG, also known as α-ketoglutarate) and chelates zinc, thus affecting a range of enzymes. 2,4-Pyridinedicarboxylic Acid (hydrate) Chemical Structure
  12. GC46503 2-(1,8-Naphthyridin-2-yl)phenol

    2-NP

     2-(1,8-Naphthyridin-2-yl)phenol is a selective enhancer of STAT1 transcription. 2-(1,8-Naphthyridin-2-yl)phenol can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells. 2-(1,8-Naphthyridin-2-yl)phenol Chemical Structure
  13. GC46553 2-Nonylquinolin-4(1H)-one

    2-n-Nonyl-4-quinolone, 2-Nonyl-1H-quinolin-4-one, 2-Nonylquinolin-4(1H)-one, Pseudane IX

     A quinolone alkaloid with diverse biological activities 2-Nonylquinolin-4(1H)-one Chemical Structure
  14. GC52446 2-Nonylquinolin-4(1H)-one-d4

    2-n-Nonyl-4-quinolone-d4, 2-Nonyl-1H-quinolin-4-one-d4, 2-Nonylquinolin-4(1H)-one-d4, Pseudane IX-d4

     An internal standard for the quantification of 2-nonylquinolin-4(1H)-one 2-Nonylquinolin-4(1H)-one-d4 Chemical Structure
  15. GC52129 3-Amino-5-hydroxybenzoic Acid

    AHBA

     3-Amino-5-hydroxybenzoic Acid Chemical Structure
  16. GC18194 4-Epidoxycycline

    4-ED

     4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline . 4-Epidoxycycline Chemical Structure
  17. GC48824 4-hydroxy Estrone

    4-hydroxy E1, 4-OHE1

     A metabolite of estrone 4-hydroxy Estrone Chemical Structure
  18. GC46673 4-octynyl Itaconate

    ITalk

     4-octynyl Itaconate (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. 4-octynyl Itaconate Chemical Structure
  19. GC52413 5-Aminosalicylic Acid-d7

    5-ASA-d7, Mesalamine-d7, Mesalazine-d7

     An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7 Chemical Structure
  20. GC92043 9(10)-Nitrooleate

    9(10)-Nitrooleic Acid; OA-NO2; 9(10)-nitro-9-trans-Octadecenoic Acid

     9(10)-Nitrooleate is a mixture of the nitroalkene endogenous lipid signaling molecules 9-nitrooleate. 9(10)-Nitrooleate Chemical Structure
  21. GC45960 9c(i472)

    15-LOX-1 Inhibitor i472

     9c(i472) is a potent inhibitor of 15-LOX-1 (15-lipoxygenase-1) with an IC50 value of 0.19 μM. 9c(i472) Chemical Structure
  22. GC42743 AEM1 Cancer cell survival appears partly dependent on antioxidative enzymes, whose expression is regulated by the Keap1-Nrf2 pathway, to quench potentially toxic reactive oxygen species generated by their metastatic transformation. AEM1 Chemical Structure
  23. GC16227 Anhydrotetracycline (hydrochloride) Anhydrotetracycline (hydrochloride) is a tetracycline biosynthetic precursor and a competitive broad-spectrum inhibitor of tetracycline destructase. Anhydrotetracycline (hydrochloride) is a regulator of the tetracycline repressor (TetR) and reverse tetracycline repressor (revTetR) transcriptional repressors in eukaryotic cells. Anhydrotetracycline (hydrochloride) Chemical Structure
  24. GC46862 Apigenin-d5

    3,6,8,3’,5’-d5-Apigenin, Chamomile-d5, Flavone-d5, Versulin-d5

     An internal standard for the quantification of apigenin Apigenin-d5 Chemical Structure
  25. GC42880 Avenanthramide-C methyl ester Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Avenanthramide-C methyl ester Chemical Structure
  26. GC48771 Avobenzone-13C-d3

    BMDBM-13C-d3, Butyl Methoxydibenzoylmethane-13C-d3

     Avobenzone-13C-d3 Chemical Structure
  27. GC45820 Balsalazide-d4 A neuropeptide with diverse biological activities Balsalazide-d4 Chemical Structure
  28. GC42925 Berteroin

    5-Methylthiopentyl isothiocyanate

     Berteroin is a sulforaphane analog found in cruciferous vegetables including Chinese cabbage, rucola salad leaves, and mustard oil. Berteroin Chemical Structure
  29. GC13231 BI 6015 HNF4α antagonist BI 6015 Chemical Structure
  30. GC19069 BI605906 BI605906 is a novel IKKβ inhibitor with an IC50 value of 380 nM when assayed at 0.1 mM ATP. BI605906 Chemical Structure
  31. GC42953 BMS 345541 (trifluoroacetate salt) BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM). BMS 345541 (trifluoroacetate salt) Chemical Structure
  32. GC42954 BMS 470539 (hydrochloride)

    BMS 470539 is an agonist of melanocortin receptor 1 (MC1R) with EC50 values of 16.8 and 11.6 nM for human and murine MC1R, respectively, in a cAMP accumulation assay.

     BMS 470539 (hydrochloride) Chemical Structure
  33. GC10233 BRD 7552 PDX1 inducer BRD 7552 Chemical Structure
  34. GC42975 BRD32048 ETS variant 1 (ETV1) is a transcription factor oncogene implicated in several cancers where it has been altered by chromosomal translocation, gene amplification, or lineage dysregulation. BRD32048 Chemical Structure
  35. GC42997 Butyrolactone I A secondary metabolite from A Butyrolactone I Chemical Structure
  36. GC43110 C8 Galactosylceramide (d18:1/8:0)

    Galactosylceramide (d18:1/8:0), N-octanoyl-βD-Galactosylceramide, GalCer(d18:1/8:0)

     C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. C8 Galactosylceramide (d18:1/8:0) Chemical Structure
  37. GC43176 CAY10575

    IKK2 Inhibitor 3, Polo-like Kinase Inhibitor 1

     CAY10575 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM. CAY10575 Chemical Structure
  38. GC43189 CAY10681 Inactivation of the tumor suppressor p53 commonly coincides with increased signaling through NF-κB in cancer. CAY10681 Chemical Structure
  39. GC43190 CAY10682 (±)-Nutlin-3 blocks the interaction of p53 with its negative regulator Mdm2 (IC50 = 90 nM), inducing the expression of p53-regulated genes and blocking the growth of tumor xenografts in vivo. CAY10682 Chemical Structure
  40. GC15474 CBFβ Inhibitor

    Core Binding Factor-β Inhibitor

     CBFβ inhibitor CBFβ Inhibitor Chemical Structure
  41. GC14266 CCG 203971

    Antifibrotic agent

     CCG 203971 Chemical Structure
  42. GC43212 CCG-232601 CCG-232601 is an inhibitor of the Rho/MRTF/SRF transcriptional pathway and a derivative of CCG-203971. CCG-232601 Chemical Structure
  43. GC48982 CD532 An inhibitor of Aurora A kinase activity and the Aurora A-N-Myc protein-protein interaction CD532 Chemical Structure
  44. GC18392 Cellocidin

    Acetylenedicarboxylic Acid, NSC 38643, NSC 65381

     Cellocidin is an antibiotic originally isolated from S. Cellocidin Chemical Structure
  45. GC52081 Chamazulene

    Dimethulene

    Chamazulene is a terpene that has been found in chamomile (M. recutita) flowers and has anti-inflammatory and antioxidant activities.

     Chamazulene Chemical Structure
  46. GC45764 Ciclopirox-d11 (sodium salt)

    HOE 296b-d11

     A neuropeptide with diverse biological activities Ciclopirox-d11 (sodium salt) Chemical Structure
  47. GC14685 CID 5951923 inhibitor of Krüppel-like factor 5 (KLF5) transcription factor CID 5951923 Chemical Structure
  48. GC13941 Cyclosporin A Immunosuppressive agent Cyclosporin A Chemical Structure
  49. GC43368 D,L-1′-Acetoxychavicol Acetate

    ACA, 1'-Acetoxychavicol Acetate, Galangal Acetate

     D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants. D,L-1′-Acetoxychavicol Acetate Chemical Structure
  50. GC45894 Daunorubicin-13C-d3 A neuropeptide with diverse biological activities Daunorubicin-13C-d3 Chemical Structure
  51. GC91805 DB2313 (hydrochloride) DB2313 is an inhibitor of the transcription factor PU. DB2313 (hydrochloride) Chemical Structure
  52. GC52194 Dimethylamino Parthenolide

    DMAPT, LC-1

     Dimethylamino Parthenolide Chemical Structure
  53. GC43493 DL-Sulforaphane N-acetyl-L-cysteine

    SFNNAC

     Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress. DL-Sulforaphane N-acetyl-L-cysteine Chemical Structure
  54. GC46148 Filgotinib-d4

    GLPG0634-d4

     An internal standard for the quantification of filgotinib Filgotinib-d4 Chemical Structure
  55. GC49344 Fisetin-d5 An internal standard for the quantification of fisetin Fisetin-d5 Chemical Structure
  56. GC18652 FQI 1

    Factor Quinolinone Inhibitor 1

     An inhibitor of Late SV40 Factor FQI 1 Chemical Structure
  57. GC18169 FX1

    An inhibitor of BCL6

     FX1 Chemical Structure
  58. GC20007 Ginsenoside CK

    Ginsenoside Compound K, Ginsenoside IH901; Compound K

    Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.

     Ginsenoside CK Chemical Structure
  59. GC91768 GSK205 (hydrobromide) GSK205 is an inhibitor of transient receptor potential vanilloid 4 (TRPV4) and transient receptor potential ankyrin 1 (TRPA1; IC50s = 4.19 and 5.56 µM, respectively, for the rat channels). GSK205 (hydrobromide) Chemical Structure
  60. GC18796 Herbicidin A Herbicidin A is an adenine nucleoside antibiotic originally isolated from S. Herbicidin A Chemical Structure
  61. GC92110 HOXB7 (8-25) (human)

    Homeobox Protein B7 (8-25)

     HOXB7 (8-25) is a peptide fragment of the transcription factor homeobox protein B7 (HOXB7). HOXB7 (8-25) (human) Chemical Structure
  62. GC47435 HPI-1 (hydrate) A Hedgehog pathway inhibitor HPI-1 (hydrate) Chemical Structure
  63. GC49742 Hsf1 Monoclonal Antibody (Clone 10H8) For immunochemical analysis of Hsf1 Hsf1 Monoclonal Antibody (Clone 10H8) Chemical Structure
  64. GC43893 iKIX1 An inhibitor of Mediator/Pdr1 interactions iKIX1 Chemical Structure
  65. GC43894 IKK2 Inhibitor VI

    5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide

    Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling.

     IKK2 Inhibitor VI Chemical Structure
  66. GC47456 Indole-3-pyruvic Acid

    Indole-3-pyruvate, IPA, IPyr, NSC 88874

     Indole-3-pyruvic Acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic Acid Chemical Structure
  67. GC49290 Indoxyl Sulfate-d5 (potassium salt) An internal standard for the quantification of indoxyl sulfate Indoxyl Sulfate-d5 (potassium salt) Chemical Structure
  68. GC48618 Isonanangenine B

    SF002-96-1

     A drimane sesquiterpene lactone Isonanangenine B Chemical Structure
  69. GC91148 JAK Inhibitor 31

    A JAK2 inhibitor

     JAK Inhibitor 31 Chemical Structure
  70. GC11197 KL 001 cryptochrome protein (CRY) stabilizer KL 001 Chemical Structure
  71. GC52283 L-Cysteine-15N-d3

    L-Cys-15N-d3, L-(+)-Cysteine-15N-d3, (R)-Cysteine-15N-d3

     An internal standard for the quantification of L-cysteine L-Cysteine-15N-d3 Chemical Structure
  72. GC45503 L-Moses (hydrochloride)

    L-45

       L-Moses (hydrochloride) Chemical Structure
  73. GC48907 Metaxalone-d6

    AHR438-d6; NSC170959-d6

     An internal standard for the quantification of metaxalone Metaxalone-d6 Chemical Structure
  74. GC49241 Methyl Diethyldithiocarbamate

    DDTC-Me, Diethyldithiocarbamic Acid methyl ester, NSC 133269

     An active metabolite of disulfiram Methyl Diethyldithiocarbamate Chemical Structure
  75. GC44216 ML-180

    CID3238389, SR1848

     ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. ML-180 Chemical Structure
  76. GC11307 ML-264 Krüppel-like factor 5 (KLF5) inhibitor ML-264 Chemical Structure
  77. GC91093 MR2938

    An AChE inhibitor

     MR2938 Chemical Structure
  78. GC92018 N,N′-Diferuloylputrescine

    bis-Ferulamidobutane; (E/Z)-Terrestribisamide

     N,N′-Diferuloylputrescine is a polyamine that has been found in Z. mays and has diverse biological activities. N,N′-Diferuloylputrescine Chemical Structure
  79. GC14832 N-3-oxo-octanoyl-L-Homoserine lactone

    3-oxo-C8-HSL,N-β-oxo-octanoyl-L-Homoserine lactone，N-(3-Oxooctanoyl)-L-homoserine; N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE

     A bacterial quorum sensing signal molecule N-3-oxo-octanoyl-L-Homoserine lactone Chemical Structure
  80. GC44459 N-pentadecanoyl-L-Homoserine lactone

    C15HSL

     Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. N-pentadecanoyl-L-Homoserine lactone Chemical Structure
  81. GC91175 NCI 126224

    A TLR4 antagonist

     NCI 126224 Chemical Structure
  82. GC44388 NF-κB Control

    SN50M

     NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. NF-κB Control Chemical Structure
  83. GC48985 NF-κB Inhibitor (trifluoroacetate salt)

    SN50 Peptide

     A cell-permeable peptide that blocks nuclear import of NF-κB NF-κB Inhibitor (trifluoroacetate salt) Chemical Structure
  84. GC12499 O4I1

    potent Oct3/4 inducer

     O4I1 Chemical Structure
  85. GC10151 OAC1 Oct4 activator OAC1 Chemical Structure
  86. GC17327 OAC2 Oct4 activator OAC2 Chemical Structure
  87. GC10724 OAC3 Oct4 activator OAC3 Chemical Structure
  88. GC44652 PK7242 (maleate) The protein p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further proliferation of the stressed cell by promoting cell cycle arrest or apoptosis. PK7242 (maleate) Chemical Structure
  89. GC45768 Pranlukast-d4

    ONO-1078-d4

     A neuropeptide with diverse biological activities Pranlukast-d4 Chemical Structure
  90. GC49860 Pyropheophorbide a methyl ester

    Methyl pyropheophorbide a, NSC 267052, PPME

     Pyropheophorbide a methyl ester (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Pyropheophorbide a methyl ester has photodynamic activity and can induce apoptosis and inhibit tumor growth. Pyropheophorbide a methyl ester Chemical Structure
  91. GC50256 RG 102240

    Gene switch ligand for use in inducible gene expression systems

     RG 102240 Chemical Structure
  92. GC12727 Ro 5-3335 Core binding factor (CBF) inhibitor Ro 5-3335 Chemical Structure
  93. GC18624 Roslin-2

    Benzylhexamethylenetetramine bromide

     Roslin-2 (Benzylhexamethylenetetramine bromide) is a p53 reactivator with anticancer effects. Roslin-2 binds FAK, disrupts the binding of FAK and p53. Roslin-2 Chemical Structure
  94. GC44888 SI-2

    EPH 116

    SI-2 is an inhibitor of steroid receptor coactivator 3 (SRC-3).

     SI-2 Chemical Structure
  95. GC49002 Sinigrin (hydrate) A glucosinolate with diverse biological activities Sinigrin (hydrate) Chemical Structure
  96. GC19523 Sivelestat sodium tetrahydrate

    EI546 sodium tetrahydrate; LY544349 sodium tetrahydrate; ONO5046 sodium tetrahydrate

     Sivelestat sodium tetrahydrate is a specific inhibitor of neutrophil elastase with an IC50 value of 14nM. Sivelestat sodium tetrahydrate Chemical Structure
  97. GC49049 SMU127

    ZINC666243

     An agonist of TLR1/2 SMU127 Chemical Structure
  98. GC44943 sPLA2 Inhibitor

    KH064, Secretory Phospholipase A2 Inhibitor

     sPLA2 Inhibitor, a D-tyrosine derivative, is an orally active, potent secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 29 nM for human nonpancreatic secretory PLA2 isoform IIa (hnpsPLA2-IIa). sPLA2 Inhibitor Chemical Structure
  99. GC48098 SR 12343 An IKKβ NBD mimetic SR 12343 Chemical Structure
  100. GC48099 SR 12460 An IKKβ NBD mimetic SR 12460 Chemical Structure
  101. GC17839 Stauprimide

    NBenzoyl7oxo Staurosporine

     Small molecule that primes embryonic stem cells (ESCs) for differentiation Stauprimide Chemical Structure

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