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PIKfyve

PIKfyve (1-phosphatidylinositol 3-phosphate 5-kinase) catalyzes the production of PtdIns5P and PtdIns(3,5)biphosphate from the phosphorylation o f D-5 position in PtdIns and phosphatidylinositol-3-phosphate. It is involved in endosome carrier vesicle biogenesis in early endosomes and endomembrane homeostasis.

Products for  PIKfyve

  1. Cat.No. Product Name Information
  2. GC31661 APY0201 APY0201 is a potent PIKfyve inhibitor, which inhibits the conversion of PtdIns3P to PtdIns(3,5)P2 in the presence of in the presence of [33P]ATP with an IC50 of 5.2 nM. APY0201  Chemical Structure
  3. GC66013 MOMIPP MOMIPP, a macropinocytosis inducer, is a PIKfyve inhibitor. MOMIPP penetrates the blood-brain barrier (BBB). MOMIPP  Chemical Structure
  4. GC69711 PIKfyve-IN-1

    PIKfyve-IN-1 is an efficient and cell-active chemical probe that can inhibit phosphoinositide 3-phosphate 5-kinase (PIKfyve) with an IC50 value of 6.9 nM. PIKfyve-IN-1 can be used for the study of PIKfyve in virology.

    PIKfyve-IN-1  Chemical Structure
  5. GC10982 YM201636 PIKfyve inhibitor,potent and selective YM201636  Chemical Structure

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