Endogenous Metabolite
Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Targets for Endogenous Metabolite
Products for Endogenous Metabolite
- Cat.No. Product Name Information
- GC60445 1-Dodecanol 1-Dodecanol is an endogenous metabolite.
- GC17829 1-Hexadecanol Fatty alcohol
-
GC68495
1-Hexadecanol-d4
1-Hexadecanol-d4 is the deuterated form of 1-hexadecanol. 1-Hexadecanol is a fatty alcohol, which is a hydrophobic substrate.
-
GC68496
1-Hexadecanol-d5
1-Hexadecanol-d5 is the deuterated form of 1-hexadecanol. 1-Hexadecanol is a fatty alcohol, which is a hydrophobic substrate.
- GC38271 1-Hydroxy-2-naphthoic acid 1-Hydroxy-2-naphthoic acid is an endogenous metabolite.
- GC38670 1-Hydroxyoctadecane 1-Hydroxyoctadecane is an endogenous metabolite.
- GC60448 1-Hydroxypyrene 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples.
- GC32294 1-Kestose A fructooligosaccharide with prebiotic and antidiabetic activities
- GC46482 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS).
- GC64598 1-Methyl-L-histidine-d3 1-Methyl-L-histidine-d3 is the deuterium labeled 1-Methyl-L-histidine.
- GC33646 1-Methyladenine 1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation.
- GC33463 1-Methyladenosine A modified nucleoside and biomarker
- GC61442 1-Methylguanidine hydrochloride 1-Methylguanidine hydrochloride is an endogenous metabolite.
- GC35067 1-Methylguanosine A methylated purine nucleoside
- GC41999 1-Methylhistamine (hydrochloride) 1-Methylhistamine (hydrochloride) is a histamine metabolite.
- GC65038 1-Methylinosine 1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
- GC42000 1-Methylnicotinamide (chloride) 1-Methylnicotinamide (chloride) (1-Methylnicotinamide chloride) is an endogenous metabolite.
-
GC31610
1-Methyluric acid
1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels.
- GC60449 1-Methylxanthine 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.
- GC35068 1-Monomyristin A monoacylglycerol
- GC38556 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine is an endogenous metabolite.
- GC30641 1-Naphthol (Fourrine ERN) 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe.
- GA20382 1-O-Octadecyl-rac-glycerol
- GC39470 1-Octanol 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents.
- GC40183 1-Oleoyl Glycerol 1-Oleoyl Glycerol is an endogenous metabolite.
- GC46488 1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PC A phospholipid
-
GC68501
1-Palmitoyl-2-oleoyl-sn-glycerol
1-Palmitoyl-2-oleoyl-sn-glycerol is an endogenous metabolite and a major diacylglycerol in hypoxia-inducible factor (HIF)-1.
- GC11139 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC A phospholipid
-
GC68502
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can be chosen as a model volatile compound for studying the molecular species of oxidized phosphatidylcholines. This method was applied to actual food samples, namely soybean lecithin.
- GC33800 10Z-Nonadecenoic acid A monounsaturated fatty acid
- GC39223 11-Beta-hydroxyandrostenedione A non-androgenic steroid
- GC40730 11-cis Vaccenyl Acetate The mating and social behaviors of insects are largely orchestrated by a suite of volatile hydrocarbon pheromones.
- GC40394 11-deoxy Corticosterone 11-deoxy Corticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor.
- GC61538 11-Oxo etiocholanolone 11-Oxo etiocholanolone (11-Ketoetiocholanolone) is a metabolite of Etiocholanolone.
- GC34016 11beta-Hydroxyprogesterone (11β-Hydroxyprogesterone) 11beta-Hydroxyprogesterone (11β-Hydroxyprogesterone) is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase; also activates human mineralocorticoid receptor in COS-7 cells with an ED50 of 10 nM.
- GC45962 12-hydroxy Lauric Acid 12-hydroxy Lauric Acid is an endogenous metabolite.
- GC60443 12-Ketodeoxycholic acid A metabolite of DCA
- GC62758 13-cis-Vitamin A palmitate 13-cis-Vitamin A palmitate (13-cis-Retinyl palmitate) is a 13-cis isomer formed by vitamin A palmitate in corn flakes.
- GC35058 16-Dehydroprogesterone 16-Dehydroprogesterone is a steroidal progestin.
- GC45909 17α-hydroxy Pregnenolone 17α-hydroxy Pregnenolone is a pregnane steroid.
- GC68426 17a-Hydroxypregnenolone-d3
- GC35061 18α-Glycyrrhetinic acid 18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism.
-
GC33818
18-Hydroxycorticosterone
18-Hydroxycorticosterone is a corticosteroid and a derivative of corticosterone, which can lead to serious electrolyte imbalances.
- GC63603 19-Hydroxyandrost-4-ene-3,17-dione
- GC38359 1H-pyrazole 1H-pyrazole is an endogenous metabolite.
- GC64738 2′-Deoxyadenosine 5′-monophosphate disodium 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA.
- GC62772 2’-Deoxyadenosine-5’-triphosphate trisodium 2’-Deoxyadenosine-5’-triphosphate trisodium (dATP trisodium) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
- GC62774 2’-Deoxyguanosine 5’-monophosphate disodium 2’-Deoxyguanosine 5’-monophosphate disodium (5′-dGMP disodium) is a mononucleotide having guanine as the nucleobase.
- GC33622 2',4'-Dihydroxyacetophenone 2',4'-Dihydroxyacetophenone (Resacetophenone) is acetophenone carrying hydroxy substituents at positions 2' and 4'.
- GC60462 2',4'-Dimethylacetophenone
- GC33605 2'-Deoxyadenosine monohydrate A deoxyribonucleoside
- GC38258 2'-Deoxyadenosine-5'-monophosphate A deoxynucleotide
- GC42150 2'-Deoxycytidine 5'-diphosphate (sodium salt hydrate) 2'-Deoxycytidine-5'-diphosphate (dCDP) trisodium is an endogenous metabolite.
- GC17436 2'-Deoxycytidine-5'-monophosphoric acid 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
- GC48440 2'-Deoxycytidine-5'-triphosphate (sodium salt) 2'-Deoxycytidine-5'-triphosphate (sodium salt) (dCTP trisodium salt) is a nucleoside triphosphate that can be used for DNA synthesis.
- GC10897 2'-Deoxyguanosine 2'-Deoxyguanosine
- GC38191 2'-Deoxyguanosine monohydrate A purine nucleoside with diverse biological activities
- GC41282 2'-O-Methyladenosine 2'-O-Methyladenosine is an analog of adenosine used to prepare nucleoside derivatives as inhibitors of viral RNA translation and replication.
- GC60452 2(5H)-Furanone
- GC39686 2,2-Dihydroxyacetic acid 2,2-Dihydroxyacetic acid is an endogenous metabolite.
- GC60457 2,3,5-Trimethylpyrazine
- GC60458 2,3-Butanediol 2,3-Butanediol is a butanediol derived from the bioconversion of natural resources.
- GC38243 2,3-Diaminopropanoic acid hydrochloride 2,3-Diaminopropanoic acid hydrochloride is an endogenous metabolite.
-
GC30672
2,3-Diaminopropionic acid
2, 3-Diaminopropionic acid is a metabolite of b-oxalyl-L-a, b-diaminopropionic acid a neurotoxic amino acid (ODAP).
- GC60463 2,4-Di-tert-butylphenol
- GC39772 2,4-Dihydroxybenzaldehyde 2,4-Dihydroxybenzaldehyde is an endogenous metabolite.
- GC33626 2,4-Dihydroxybenzoic acid 2,4-Dihydroxybenzoic acid is a degradation product of cyaniding glycoside from tart cheeries in cell culture.
- GC38367 2,4-Dihydroxypyrimidine-5-carboxylic Acid 2,4-Dihydroxypyrimidine-5-carboxylic Acid is an endogenous metabolite.
- GC33519 2,5-Dihydroxybenzoic acid A benzoic acid with diverse biological activities
- GC38729 2,5-Dimethylpyrazine 2,5-Dimethylpyrazine is an endogenous metabolite.
- GC33637 2,5-Furandicarboxylic acid 2,5-Furandicarboxylic acid, detected in human urine, is an important renewable biotechnological building block because it serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters.
- GA20387 2,6-Diaminopimelic acid 2,6-Diaminopimelic acid is an endogenous metabolite.
- GC39773 2,6-Dibromophenol 2,6-Dibromophenol is an endogenous metabolite.
- GC39767 2,6-Dihydroxyacetophenone 2,6-Dihydroxyacetophenone is an endogenous metabolite.
- GC33642 2,6-Dihydroxybenzoic acid 2,6-Dihydroxybenzoic acid is a secondary metabolite of salicylic acid which has been hydrolyzed by liver enzymes during phase I metabolism.
- GC33643 2,6-Dimethoxybenzoic acid 2,6-Dimethoxybenzoic acid is a member of organic compounds known as o-methoxybenzoic acids and derivatives.
- GC39768 2,6-Dimethylhydroquinone
- GC62766 2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate 2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate is an endogenous metabolite.
- GC65461 2,8-Dihydroxyadenine 2,8-Dihydroxyadenine, an endogenous metabolite, can cause the formation of urinary crystals and kidney stones.
- GC30697 2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine 2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine is a histamine (Him) metabolite.
- GC38301 2-(1H-Indol-3-yl)ethan-1-ol An indole with diverse biological activities
- GC62763 2-(2’,3’,4’-Trihydroxybutyl)quinoxaline 2-(2’,3’,4’-Trihydroxybutyl)quinoxaline is a food metabolite.
- GC33633 2-(2-Methylbenzamido)acetic acid 2-(2-Methylbenzamido)acetic acid is a metabolite detected in urine.
-
GC68504
2-(2-Methylbenzamido)acetic acid-d7
2-(2-Methylbenzamido)acetic acid-d7 is the deuterated form of 2-(2-Methylbenzamido)acetic acid. 2-(2-Methylbenzamido)acetic acid is a metabolite that can be detected in urine.
- GC34193 2-(4-Methoxyphenyl)acetic acid (4-Methoxyphenylacetic acid) 2-(4-Methoxyphenyl)acetic acid (4-Methoxyphenylacetic acid) is a plasma metabolite, with high sensitivity and specificity value as a biomarker for discriminating between NSCLC and healthy controls.
- GC33496 2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) 2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) (N2-Methylguanine) is a modified nucleoside.
- GC12964 2-3-Dihydroxybenzoic acid 2-3-Dihydroxybenzoic acid is a normal human benzoic acid metabolite found in plasma, and has increased levels after aspirin ingestion.
- GC39844 2-Acetonaphthone 2-Acetonaphthone is an endogenous metabolite.
- GC60469 2-Acetyl-3-ethylpyrazine 2-Acetyl-3-ethylpyrazine is an endogenous metabolite.
- GC30718 2-Amino-1-phenylethanol 2-Amino-1-phenylethanol is an analogue of noradrenaline.
- GC62769 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid is an endogenous metabolite.
- GC60470 2-Amino-5-phenylpyridine 2-Amino-5-phenylpyridine is a mutagenic heterocyclic aromatic amine that is formed by pyrolysis of phenylalanine in proteins. 2-Amino-5-phenylpyridine is in broiled sardines and is considered as potentially carcinogenic.
- GC62770 2-Amino-5-ureidopentanoic acid 2-Amino-5-ureidopentanoic acid is an endogenous metabolite.
- GC38260 2-Aminobenzenesulfonic acid 2-Aminobenzenesulfonic acid is an endogenous metabolite.
- GC38321 2-Aminopyrimidin-5-ol
-
GC16403
2-Arachidonoyl Glycerol
An endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2
- GC12850 2-Deoxy-D-ribose 2-Deoxy-D-ribose is an endogenous metabolite.
- GC11642 2-Deoxyadenosine 2-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
- GC17478 2-Deoxycytidine A deoxyribonucleoside
- GC11581 2-Deoxyinosine A nucleoside form of hypoxanthine