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Matrix metalloproteinases (MMPs) are a family of zinc-dependent neutral endopeptidases, generally consisting of a single peptide, a propeptide domain, a catalytic domain with a highly conserved zinc-binding site and a haemopexin-like domain, that catalyze the degradation of all components of the extracellular matrix. Multiple studies have shown that MMPs are overexpressed in malignant tumor and involved in the process of tumor growth, invasion and metastasis. Thus, synthetic and naturally occurring MMP inhibitions have been investigated as anti-cancer agents for the treatment of a variety of cancers, which are divided into three pharmacologic categories, including collagen peptidomimetics and nonpeptidomimetics, tetracycline derivatives and bisphosphonates.

  1. Cat.No. Product Name Information
  2. GC17242 (-)-epigallocatechin green tea epicatechin
  3. GN10783 (R) Ginsenoside Rh2 Extracted from Panax ginseng C. A. Mey. dried roots;Store the product in sealed, cool and dry condition
  4. GC41776 1,2,3-Trioleoyl-rac-glycerol 1,2,3-Trioleoyl-rac-glycerol is a triacylglycerol that contains oleic acid at the sn-1, sn-2, and sn-3 positions.
  5. GC16350 Actinonin Peptidomimetic antibiotic that inhibits aminopeptidases
  6. GP10057 Amyloid β-Peptide (10-20) (human)

    Initiates neurodegeneration in Alzheimer disease

  7. GC35369 Apigenin-7-glucuronide
  8. GC35377 Apratastat
  9. GN10063 Arctigenin Anti-inflammatory, antiproliferative
  10. GC13487 ARP 100

    Selective MMP-2 inhibitor

  11. GC12465 ARP 101 MMP inhibitor,potent and selective
  12. GN10494 Astragaloside IV Anti-inflammatory;extract of Astragali radix
  13. GC42873 Auraptene Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7.
  14. GC16530 Batimastat (BB-94)

    MMP inhibitor

  15. GC35470 Batimastat sodium salt
  16. GC32442 BR351
  17. GC33365 BR351 precursor
  18. GN10342 Chondroitin sulfate Extracted from shark bone;Store the product in sealed, cool and dry condition
  19. GC10149 cis-ACCP type IV collagen-specific MMP-2 and MMP-9 inhibitor
  20. GC15952 CL 82198 hydrochloride Selective MMP-13 inhibitor
  21. GN10810 Cordycepin Extracted from Cordyceps;Store the product in sealed, cool and dry condition

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