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Stem Cell

Products for  Stem Cell

  1. Cat.No. Product Name Information
  2. GC11548 Tankyrase Inhibitors (TNKS) 49 Tankyrase inhibitor Tankyrase Inhibitors (TNKS) 49  Chemical Structure
  3. GC13576 TC-G 24

    GSK-3β inhibitor

    TC-G 24  Chemical Structure
  4. GC31268 tCFA15 tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notch signaling. tCFA15  Chemical Structure
  5. GC10440 TCS 183 competitive inhibitor of GSK-3β (Ser9) phosphorylation TCS 183  Chemical Structure
  6. GC11515 TCS 184 Scrambled control peptide for use with TCS 183 TCS 184  Chemical Structure
  7. GC11627 TCS 2002 TCS 2002 (Compound 9b) is a highly selective, orally bioavailable and potent GSK-3β inhibitor with the IC50 of 35 nM. TCS 2002  Chemical Structure
  8. GC13301 TCS 2210 Inducer of neuronal differentiation in mesenchymal stem cells (MSCs) TCS 2210  Chemical Structure
  9. GC65889 TDI-011536 TDI-011536 is a potent Lats kinase inhibitor, interrupts Hippo-Yap signaling and initiates the proliferation of lesioned heartmuscle cells. TDI-011536 can be used in studies of organ conservation and regeneration. TDI-011536  Chemical Structure
  10. GC14840 TDZD-8 GSK-3β inhibitor TDZD-8  Chemical Structure
  11. GC65185 TEAD-IN-2 TEAD-IN-2 is a novel, orally active inhibitor of transcriptional enhancer associate domain (TEAD) and modulates TEAD by ubiquitination and/or degradation by compounds. TEAD-IN-2 can be used for the research of a variety of diseases, disorders or conditions associated with TEAD. TEAD-IN-2  Chemical Structure
  12. GC70003 TEAD-IN-3

    TEAD-IN-3 (compound I-177) is an effective inhibitor of the TEAD transcription factor. TEAD-IN-3 can be used for research on proliferative diseases such as cancer.

    TEAD-IN-3  Chemical Structure
  13. GC39159 Tegatrabetan Tegatrabetan (BC2059) is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1). Tegatrabetan  Chemical Structure
  14. GC62394 Teplinovivint Teplinovivint is a potent wnt/β-catenin signaling pathway inhibitor. Teplinovivint  Chemical Structure
  15. GC14465 Tideglusib non-ATP-competitive GSK-3β inhibitor Tideglusib  Chemical Structure
  16. GC64131 TMX-4116 TMX-4116 is a casein kinase 1α (CK1α) degrader. TMX-4116 shows the degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4116 can be used for the research of multiple myeloma. TMX-4116  Chemical Structure
  17. GC45090 Triparanol Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol. Triparanol  Chemical Structure
  18. GC14037 Triptonide A diterpenoid with diverse biological activities Triptonide  Chemical Structure
  19. GC17868 TWS119

    GSK-3β inhibitor

    TWS119  Chemical Structure
  20. GC15284 U 18666A

    U18666A can inhibit 3β-hydroxysterol-Δ (24)-reductase (DHCR24) activity, thereby preventing cholesterol outflow from late endosomes and lysosomes.

    U 18666A  Chemical Structure
  21. GC17535 UM 191 UM 191 UM 191  Chemical Structure
  22. GC11424 Valproic acid HDAC1 inhibitor Valproic acid  Chemical Structure
  23. GC45137 Valproic Acid Acyl-D-Glucuronide Valproic acid acyl-D-glucuronide is the major urinary metabolite of valproic acid. Valproic Acid Acyl-D-Glucuronide  Chemical Structure
  24. GC15794 Valproic acid sodium salt (Sodium valproate) A class I HDAC inhibitor Valproic acid sodium salt (Sodium valproate)  Chemical Structure
  25. GC64378 Valproic acid-d6 Valproic acid-d6 (VPA-d6) is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid-d6  Chemical Structure
  26. GC14482 Verteporfin

    Verteporfin is a potent inhibitor of PD-L1 expression used for treatment in the age-related macular degeneration , port-wine stain birthmarks and cancer.

    Verteporfin  Chemical Structure
  27. GC37923 VP3.15 VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15  Chemical Structure
  28. GC37924 VP3.15 dihydrobromide VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide  Chemical Structure
  29. GC70131 VT02956

    VT02956 is a LATS inhibitor (IC50: 0.76 nM for LATS1 and 0.52 nM for LATS2). It targets the Hippo signaling pathway and inhibits the growth of ER+ breast cancer cell lines and tumor organoids derived from patients, as well as ESR1 expression.

    VT02956  Chemical Structure
  30. GC63257 VT103 VT103, an analog of VT101, is an orally active and selective TEAD1 protein palmitoylation inhibitor. VT103 inhibits YAP/TAZ-TEAD promoted gene transcription, blocks TEAD auto-palmitoylation, and disrupts interaction between YAP/TAZ and TEAD. VT103 can be used for the research of cancer. VT103  Chemical Structure
  31. GC70132 VT104

    VT104 is an orally effective inhibitor of YAP/TAZ. It prevents the palmitoylation of endogenous TEAD1 and TEAD3 proteins. VT104 can be used in cancer research.

    VT104  Chemical Structure
  32. GC62524 VT107 VT-107, as an analogous to VT104, is an orally active and potent pan-TEAD auto-palmitoylation inhibitor. VT-107 can be used for the research of cancer. VT107  Chemical Structure
  33. GC50077 WAY 316606 hydrochloride Secreted Frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling WAY 316606 hydrochloride  Chemical Structure
  34. GC26049 WAY-119064 WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM. WAY-119064  Chemical Structure
  35. GC15753 WAY-262611 β-Catenin agonist WAY-262611  Chemical Structure
  36. GC70143 WIC1

    WIC1 is an effective Wnt inhibitor that can be used in cancer research.

    WIC1  Chemical Structure
  37. GC11674 WIKI4 A potent TNKS1/2 inhibitor WIKI4  Chemical Structure
  38. GC12133 Windorphen Wnt inhibitor Windorphen  Chemical Structure
  39. GC17764 Wnt agonist 1 Wnt agonist 1 is a potent and cell-permeable Wnt signaling activator. Wnt agonist 1 induces TCF-dependent transcriptional activity with an EC50of 700 nM. Wnt agonist 1  Chemical Structure
  40. GC70148 Wnt pathway activator 2

    Wnt pathway activator 2 is an effective Wnt activator with an EC50 value of 13 nM. For more information, please refer to patent WO2012024404A1, compound 2.

    Wnt pathway activator 2  Chemical Structure
  41. GC13658 Wnt-C59 PORCN inhibitor,highly potent and selective Wnt-C59  Chemical Structure
  42. GC37937 Wnt/β-catenin agonist 1 Wnt/β-catenin agonist 1 (compound 3f) is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM. Wnt/β-catenin agonist 1  Chemical Structure
  43. GC63695 Wnt/β-catenin agonist 2 Wnt/β-catenin agonist 2 is a potent Wnt agonist. Wnt/β-catenin agonist 2  Chemical Structure
  44. GC66039 Wnt/β-catenin agonist 3 Wnt/β-catenin agonist 3 (compound 98) is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 can be used for the research of osteoporosis. Wnt/β-catenin agonist 3  Chemical Structure
  45. GC70149 Wnt/β-catenin agonist 3 hydrochloride

    Wnt/β-catenin agonist 3 hydrochloride is a Wnt/β-catenin signaling pathway activator. Wnt/β-catenin agonist 3 (compound 98) can be used for research on osteoporosis.

    Wnt/β-catenin agonist 3 hydrochloride  Chemical Structure
  46. GC68028 Wnt/β-catenin agonist 4 Wnt/β-catenin agonist 4  Chemical Structure
  47. GN10017 Wogonin Wogonin  Chemical Structure
  48. GC12781 XAV-939

    XAV-939 selectively inhibits β-catenin-mediated transcription.

    XAV-939  Chemical Structure
  49. GC11245 XMU-MP-1

    MST1/2 inhibitor, potent and selective

    XMU-MP-1  Chemical Structure
  50. GC26088 YAP-TEAD Inhibitor 1 (Peptide 17) YAP-TEAD Inhibitor 1 (Peptide 17) is a YAP-TEAD protein-protein interaction inhibitor which has potential usage in treatment of YAP-involved cancers with IC50 of 25 nM. YAP-TEAD Inhibitor 1 (Peptide 17)  Chemical Structure
  51. GC39461 YAP-TEAD-IN-1 TFA YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of?YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd= 40 nM). YAP-TEAD-IN-1 TFA  Chemical Structure
  52. GC65131 YAP/TAZ inhibitor-2 YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative activity. YAP/TAZ inhibitor-2 shows antitumor activity. YAP/TAZ inhibitor-2  Chemical Structure
  53. GC63303 YB-0158

    YB-0158 is known as Wnt pathway inhibitor 2.

    YB-0158  Chemical Structure
  54. GC50703 Yhhu 3792 Yhhu 3792  Chemical Structure
  55. GC17671 YO-01027 (Dibenzazepine, DBZ) An inhibitor of γ-secretase YO-01027 (Dibenzazepine, DBZ)  Chemical Structure
  56. GC45596 YW1128   YW1128  Chemical Structure
  57. GC15896 Z-Ile-Leu-aldehyde potent gamma-Secretase inhibitor Z-Ile-Leu-aldehyde  Chemical Structure
  58. GC18533 ZLDI-8

    Temiverine hydrochloride is a synthesized drug that is expected to have anticholinergic action.

    ZLDI-8  Chemical Structure
  59. GC63560 ZW4864 ZW4864 is an orally active and selective β catenin/B-Cell lymphoma 9 protein?protein interaction (β catenin/BCL9 PPI) inhibitor. ZW4864 inhibits β catenin/BCL9 PPI with a Ki value of 0.76 μM and an IC50 value of 0.87 μM. ZW4864  Chemical Structure
  60. GC63559 ZW4864 free base ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein?protein interaction (β catenin/BCL9 PPI) inhibitor. ZW4864 (free base) inhibits β catenin/BCL9 PPI with a Ki value of 0.76 μM and an IC50 value of 0.87 μM. ZW4864 free base  Chemical Structure

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