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Hedgehog

Hh (Hedgehog) signalling is a evolutionarily conserved pathway that is critical for embryonic development, tissue and organ morphogenesis. Mammalian Hh protein ligands include Sonic Hh, Desert Hh and Indian Hh. Dysfunctions of Hh singalling lead to developmental abnormalities and cancer.

  1. Cat.No. Product Name Information
  2. GC15422 20(S)-Hydroxycholesterol Allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein
  3. GC12429 AY 9944 dihydrochloride Hedgehog Inhibitor
  4. GC14715 AZ 12080282 dihydrochloride Hedgehog inhibitor
  5. GC17153 CHIR-99021 (CT99021) HCl GSK-3α/β inhibitor
  6. GC11476 Ciliobrevin A

    Hh pathway antagonist

  7. GC11217 CUR 61414 potent inhibitor of hedgehog-induced cellular activity
  8. GC13441 Cyclopamine Hedgehog (Hh) signaling Inhibitor
  9. GC16789 GANT 58 GLI antagonist,novel and potent
  10. GC10359 GANT61 GLI antagonist
  11. GC10493 GDC-0449 (Vismodegib)

    Hedgehog antagonist,potent and selective

  12. GC11045 HPI 1 Hh signaling inhibitor
  13. GC11111 Jervine Hedgehog signaling Inhibitor
  14. GC15256 JK 184 Hh signaling inhibitor
  15. GC15683 LY2940680 Hedgehog/SMO antagonist,inhibits Hh signaling
  16. GC13630 MK-4101 Hedgehog (Hh) signaling pathway inhibitor
  17. GC38522 Neurodazine
  18. GC17713 Oxy-16 antagonist of hedgehog activity
  19. GC13280 PF-5274857 Smo antagonist,potent and selective
  20. GC15064 Purmorphamine Hedgehog agonist
  21. GC37573 RU-SKI 43

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