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Home >> Signaling Pathways >> TGF-β / Smad Signaling >> PKC

PKC

PKC (protein kinase C) is a serine/threonine protein kinase that mediates insulin signaling, actin cytoskeleton, cell mobility, apoptosis and tumorigenesis etc.

Products for  PKC

  1. Cat.No. Product Name Information
  2. GC13890 (±)-Palmitoylcarnitine chloride

    C16:0 Carnitine, CAR 16:0, DL-Carnitine hexadecanoyl ester, DL-Carnitine palmitoyl ester, Hexadecanoyl-DL-carnitine, DL-Hexadecanoylcarnitine, NSC 628323, DL-Palmitoylcarnitine

     intermediate in mitochondrial fatty acid oxidation (±)-Palmitoylcarnitine chloride Chemical Structure
  3. GC10603 (-)-epicatechin gallate

    ECG

     major catechin in green tea (-)-epicatechin gallate Chemical Structure
  4. GC17242 (-)-epigallocatechin

    (-)EGC, epi-Gallocatechin, NSC 674039

     green tea epicatechin (-)-epigallocatechin Chemical Structure
  5. GC14049 (-)-Epigallocatechin gallate (EGCG)

    EGCG

     (-)-Epigallocatechin Gallate sulfate (EGCG) is a major polyphenol in green tea that inhibits cell proliferation and induces apoptosis. (-)-Epigallocatechin gallate (EGCG) Chemical Structure
  6. GC14012 (-)-Indolactam V A protein kinase C activator (-)-Indolactam V Chemical Structure
  7. GC70295 (S)-Ro 32-0432 (S)-Ro 32-0432 is a potent, selective, ATP-competitive and orally active PKC inhibitor. (S)-Ro 32-0432 Chemical Structure
  8. GC18062 1,2-Dilauroyl-sn-glycerol

    1,2-DLG

     A longchain DAG 1,2-Dilauroyl-sn-glycerol Chemical Structure
  9. GC14134 1,2-Dimyristoyl-sn-glycerol

    1,2-DMG

     A longchain DAG 1,2-Dimyristoyl-sn-glycerol Chemical Structure
  10. GC13877 1,2-Dipalmitoyl-sn-glycerol

    1,2-DPG,NSC 269964

    weak activator of PKC

     1,2-Dipalmitoyl-sn-glycerol Chemical Structure
  11. GC12662 1,2-Distearoyl-sn-glycerol

    1,2-Dioctadecanoyl-sn-glycerol,DSG

     A diacylglycerol 1,2-Distearoyl-sn-glycerol Chemical Structure
  12. GN10444 12-O-tetradecanoyl phorbol-13-acetate

    PMA; TPA; Phorbol myristate acetate

    A PKC activator

     12-O-tetradecanoyl phorbol-13-acetate Chemical Structure
  13. GC60037 A-3 hydrochloride A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride Chemical Structure
  14. GC16475 Afuresertib

    GSK2110183

     pan-AKT inhibitor Afuresertib Chemical Structure
  15. GC42747 Afuresertib (hydrochloride)

    GSK2110183B

     Afuresertib is a selective, orally bioavailable inhibitor of Akt1, 2, and 3 with Ki values of 0.08, 2, and 2.6 nM, respectively. Afuresertib (hydrochloride) Chemical Structure
  16. GC68679 Aprinocarsen sodium

    ISIS 3521 sodium

    Aprinocarsen (ISIS 3521) sodium is a specific antisense oligonucleotide inhibitor of protein kinase C-alpha (PKC-alpha). Aprinocarsen sodium is a 20-mer oligonucleotide that can regulate cell differentiation and proliferation. It can inhibit the growth of human tumor cell lines in nude mice. Aprinocarsen sodium has value as a chemotherapy compound for human cancer.

     Aprinocarsen sodium Chemical Structure
  17. GC31959 AS2521780 AS2521780 is a novel PKCθ selective inhibitor with an IC50 of 0.48 nM. AS2521780 Chemical Structure
  18. GC64815 Aurothiomalate sodium Aurothiomalate sodium is a potent and selective oncogenic PKCι signaling inhibitor. Aurothiomalate sodium Chemical Structure
  19. GC12135 Bisindolylmaleimide II

    BIM II

     protein kinase C (PKC) inhibitor Bisindolylmaleimide II Chemical Structure
  20. GC14716 Bisindolylmaleimide IV

    Arcyriarubin A,BIM IV

     Bisindolylmaleimide IV is a potent cell-permeable inhibitor of protein kinase C (PKC) with IC50 values are 0.1- 0.55μM. Bisindolylmaleimide IV Chemical Structure
  21. GC17239 Bisindolylmaleimide V

    BIM V, Ro 316045

     negative control for protein kinase C (PKC)-inhibitory activity Bisindolylmaleimide V Chemical Structure
  22. GC13226 Bisindolylmaleimide VIII (acetate)

    BIM VIII,Ro 31-7549

     A protein kinase C (PKC) inhibitor Bisindolylmaleimide VIII (acetate) Chemical Structure
  23. GC18354 Bisindolylmaleimide X (hydrochloride)

    BIM X, Ro 31-8425

     Bisindolylmaleimide X is a cell-permeable, reversible, ATP-competitive protein kinase C (PKC) inhibitor (IC50 = 15 nM, rat brain PKC). Bisindolylmaleimide X (hydrochloride) Chemical Structure
  24. GC35530 BJE6-106

    B106

     BJE6-106 (B106) is a potent, selective 3rd generation PKCδ inhibitor with an IC50 of 0.05 μM and targets selectivity over classical PKC isozyme PKCα (IC50=50 μM). BJE6-106 Chemical Structure
  25. GC17670 Bryostatin 1

    NSC 339555

     PKC activator Bryostatin 1 Chemical Structure
  26. GC12842 Bryostatin 2 Protein kinase C (PKC) activator Bryostatin 2 Chemical Structure
  27. GC12695 Bryostatin 3 protein kinase C activator Bryostatin 3 Chemical Structure
  28. GC11605 C-1 C-1 is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. C-1 also used as a ROCK inhibitor. C-1 Chemical Structure
  29. GC43105 C8 Ceramide (d18:1.8:0)

    N-octanoyl-D-erythro-Sphingosine

     C8 Ceramide (d18:1.8:0) (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8 Ceramide (d18:1.8:0) Chemical Structure
  30. GC11159 Calphostin C

    Cladochrome E, PKF 115584, UCN 1028C

    protein kinase C inhibitor

     Calphostin C Chemical Structure
  31. GC62612 CC-90005 CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 Chemical Structure
  32. GC73183 CDK8-IN-12 CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM. CDK8-IN-12 Chemical Structure
  33. GC18521 Cercosporin

    CGP 049090, NSC 153111

     Cercosporin is a pigmented phytotoxin isolated from the fungus C. Cercosporin Chemical Structure
  34. GC10687 CGP 53353

    DAPH-7

     PKCβII inhibitor CGP 53353 Chemical Structure
  35. GC14650 CGP60474 A CDK inhibitor CGP60474 Chemical Structure
  36. GN10463 Chelerythrine Chelerythrine Chemical Structure
  37. GC13065 Chelerythrine Chloride

    Broussonpapyrine chloride, NSC 646662

     Potent inhibitor of PKC and Bcl-xL Chelerythrine Chloride Chemical Structure
  38. GC43286 CMPD101 A GRK2 and GRK3 inhibitor CMPD101 Chemical Structure
  39. GC50704 CRT 0066854 hydrochloride CRT 0066854 hydrochloride is a potent and selective atypical PKCs inhibitor. CRT 0066854 hydrochloride Chemical Structure
  40. GC45414 CRT0066854   CRT0066854 Chemical Structure
  41. GC17591 D-erythro-Sphingosine (synthetic)

    (-)Sphingosine, DerythroSphingosine C18

     D-erythro-sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 value of 8μM. D-erythro-Sphingosine (synthetic) Chemical Structure
  42. GN10336 Daphnetin

    7,8-Dihydroxycoumarin, NSC 633563

     Daphnetin Chemical Structure
  43. GC38186 Daphnoretin

    NSC 291852

     A coumarin with diverse biological activities Daphnoretin Chemical Structure
  44. GC38388 DCPLA-ME

    DCPLA methyl ester

     DCPLA-ME, the methyl ester form of DCPLA, is a potent PKCε activator for use in the treatment of neurodegenerative diseases. DCPLA-ME Chemical Structure
  45. GC31892 Decursin ((+)-Decursin)

    (+)-Decursin

     Decursin ((+)-Decursin) ((+)-Decursin ((+)-Decursin)) is a potent anti-tumor agent. Decursin ((+)-Decursin) Chemical Structure
  46. GC16354 Dequalinium Chloride

    NSC 166454

     anti-tumor agent and PKC inhibitor Dequalinium Chloride Chemical Structure
  47. GC38482 Desmethylglycitein

    6-hydroxy Daidzein, 6,7,4’-THIF

     Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities.Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1). Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes. Desmethylglycitein Chemical Structure
  48. GC17767 Dihydrosphingosine Dihydrosphingosine is a potent inhibitor of PKC and phospholipase A2 (PLA2). Dihydrosphingosine Chemical Structure
  49. GC90543 EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt)

    A PKC inhibitor

     EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt) Chemical Structure
  50. GC11499 Enzastaurin (LY317615)

    LY317615

     Enzastaurin (LY317615) (LY317615) is a potent and selective PKCβ inhibitor with an IC50 of 6 nM, showing 6- to 20-fold selectivity over PKCα, PKCγ and PKCε. Enzastaurin (LY317615) Chemical Structure
  51. GC13869 Fasudil Fasudil (HA-1077; AT877) is a non-specific RhoA/ROCK inhibitor with a Ki of 0.33μM and an IC50 of 0.158μM for ROCK1, and IC50 of 4.58μM, 12.30μM, and 1.650μM for ROCK2, PKA, PKC, and PKG, respectively. Fasudil Chemical Structure
  52. GC14289 Fasudil (HA-1077) HCl Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil (HA-1077) HCl is also a potent Ca2+ channel antagonist and vasodilator. Fasudil (HA-1077) HCl Chemical Structure
  53. GC12027 FR 236924

    FR 236924

     FR 236924 (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. FR 236924 Chemical Structure
  54. GC15431 GF 109203X (Bisindolylmaleimide I)

    Gö 6850;Bisindolylmaleimide I

     GF 109203X is a selective inhibitor of protein kinase C, selective for the α and β1 isoforms with IC50 values of 0.0084, 0.0180, 0.210, 0.132, and 5.8μM for α, β1, δ, ε and ζ isoforms of protein kinase C respectively. GF 109203X (Bisindolylmaleimide I) Chemical Structure
  55. GC15564 Go 6976

    Go6976;Go-6976

     PKCα/PKCβ1 inhibitor Go 6976 Chemical Structure
  56. GC16907 Go 6983

    Goe 6983;Go6983;Go-6983

     Go 6983 (GÖ 6983) is one of the bisindolylmaleimide group of PKC inhibitor compounds, Go 6983 (GÖ 6983) was able to differentiate between PKC mu and other PKC isoenzymes. Go 6983 Chemical Structure
  57. GC10299 Hexadecyl Methyl Glycerol

    1-O-hexadecyl-2-O-methyl-sn-Glycerol

     protein kinase C activity inhibitor Hexadecyl Methyl Glycerol Chemical Structure
  58. GC15018 Hispidin protein kinase Cβ inhibitor Hispidin Chemical Structure
  59. GC36282 Hypocrellin A Hypocrellin A, a naturally occurring PKC inhibitor, has many biological and pharmacological properties, such as antitumour, antiviral, antibacterial, and antileishmanial activities. Hypocrellin A Chemical Structure
  60. GC15420 ICP 103 Protein kinase inhibitor ICP 103 Chemical Structure
  61. GC32870 Ingenol ((-)-Ingenol) Ingenol ((-)-Ingenol) is a PKC activator, with a Ki of 30 μM, with antitumor activity. Ingenol ((-)-Ingenol) Chemical Structure
  62. GC61776 Ingenol 3,20-dibenzoate Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate Chemical Structure
  63. GC31656 Ingenol Mebutate (Ingenol 3-angelate)

    Ingenol Mebutate, 3Ingenyl Angelate, PEP005, Picato

     Ingenol Mebutate (Ingenol 3-angelate) is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity. Ingenol Mebutate (Ingenol 3-angelate) Chemical Structure
  64. GC15148 Ionomycin calcium salt Ionomycin calcium salt is a narrow spectrum antibiotic being active against Gram-positive bacteria, which produced by the bacterium Streptomyces conglobatus. Ionomycin calcium salt Chemical Structure
  65. GC15446 Ionomycin free acid

    Ionomycin free acid is a selective and potent calcium ion carrier that acts as an active Ca2+ carrier.

     Ionomycin free acid Chemical Structure
  66. GC11362 K 252a

    SF 2370

     A protein kinase inhibitor K 252a Chemical Structure
  67. GC15281 K-252c

    Staurosporinone

     Protein kinase inhibitor K-252c Chemical Structure
  68. GC43993 K252b K252b is an indolocarbazole isolated from the actinomycete Nocardiopsis, first described as an inhibitor of protein kinase C. K252b Chemical Structure
  69. GC64263 Kobophenol A Kobophenol A, an oligomeric stilbene, blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. Kobophenol A Chemical Structure
  70. GC17346 KT 5823 A protein kinase G inhibitor KT 5823 Chemical Structure
  71. GC40770 L-erythro Sphingosine (d18:1)

    L-erythro Sphingosine, L-erythro-C18-Sphingosine

     L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1). L-erythro Sphingosine (d18:1) Chemical Structure
  72. GC17815 L-threo-Sphingosine C-18

    L-threo-Sphingosine C18

     L-threo-Sphingosine C-18 is a potent MAPK inhibitor. L-threo-Sphingosine C-18 induces apoptosis and clear DNA fragmentation. L-threo-Sphingosine C-18 shows anticancer effect. L-threo-Sphingosine C-18 Chemical Structure
  73. GC32811 LXS196

    LXS196; IDE196

     LXS196 (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. LXS196 has the potential for uveal melanoma research. LXS196 Chemical Structure
  74. GC17563 LY 333531 hydrochloride

    Ruboxistaurin

     Ruboxistaurin (LY333531) hydrochloride is an orally active, selective PKC beta inhibitor (Ki=2 nM). LY 333531 hydrochloride Chemical Structure
  75. GC48345 Lyso-Monosialoganglioside GM2 (ammonium salt)

    Lysoganglioside GM2, Lyso-GM2, lyso-Monosialoganglioside GM2

     Lyso-Monosialoganglioside GM2 (ammonium salt) Chemical Structure
  76. GC30545 Malantide Malantide is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts. Malantide is also an efficient substrate for PKC with a Km of 16 μM. Malantide Chemical Structure
  77. GC10496 Midostaurin (PKC412)

    CGP 41251

     Midostaurin (PKC412) (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin (PKC412) inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM. Midostaurin (PKC412) also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin (PKC412) shows powerful anticancer effects. Midostaurin (PKC412) Chemical Structure
  78. GC32714 Mitoxantrone (mitozantrone) Mitoxantrone is an antitumor anthrandione derivative. Mitoxantrone (mitozantrone) Chemical Structure
  79. GC14363 Mitoxantrone HCl

    NCI 301739, NSC 301739

     Mitoxantrone HCl is a potent topoisomerase II inhibitor. Mitoxantrone HCl Chemical Structure
  80. GC74326 MPSD TFA

    MARCKS-ED TFA

     MPSD TFA (MARCKS-ED TFA) is the TFA salt form of MPSD. MPSD TFA Chemical Structure
  81. GC63778 Myelin Basic Protein TFA

    MHP4-14 TFA

     Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA Chemical Structure
  82. GC49269 Myr-ZIP

    Myristoylated-ZIP, Myristoylated Zeta-Pseudosubstrate Inhibitory Peptide, Myr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu, Myr-SIYRRGARRWRKL-OH, Ζeta Inhibitory Peptide

     A PKMζ inhibitor Myr-ZIP Chemical Structure
  83. GC25662 N-Desmethyltamoxifen N-Desmethyltamoxifen, the major metabolite of Tamoxifen in humans and a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen, also is a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. N-Desmethyltamoxifen Chemical Structure
  84. GC38931 N-Desmethyltamoxifen hydrochloride N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. N-Desmethyltamoxifen hydrochloride Chemical Structure
  85. GC74419 N-myristoyl-RKRTLRRL N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL Chemical Structure
  86. GC60274 O-Desmethyl Midostaurin

    CGP62221; O-Desmethyl PKC412

     O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo. Midostaurin is a multi-targeted protein kinase inhibitor?with?IC50?ranging from 22-500 nM. O-Desmethyl Midostaurin Chemical Structure
  87. GC36833 p32 Inhibitor M36

    M36

     p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1. p32 Inhibitor M36 Chemical Structure
  88. GC61585 Pep2m, myristoylated TFA

    Myr-Pep2m TFA

     Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA Chemical Structure
  89. GC17352 Phorbol 12,13-dibutyrate

    PDBu

     Protein kinase C activator Phorbol 12,13-dibutyrate Chemical Structure
  90. GC73968 Pim-1 kinase inhibitor 8 Pim-1 kinase inhibitor 8 (compound 12) is a potent inhibitor of Pim-1 kinase with an IC50 of 14.3 nM. Pim-1 kinase inhibitor 8 Chemical Structure
  91. GC15471 PKC β pseudosubstrate Selective cell-permeable peptide inhibitor of protein kinase C PKC β pseudosubstrate Chemical Structure
  92. GC10404 PKC ζ pseudosubstrate PKC ζ pseudosubstrate is a selective cell-permeable inhibitor of PKC. PKC ζ pseudosubstrate Chemical Structure
  93. GC11671 PKC fragment (530-558) Potent activator of protein kinase C PKC fragment (530-558) Chemical Structure
  94. GC61995 PKCβ inhibitor 1

    Protein Kinase Cβ Inhibitor

     PKCβ inhibitor 1 is a potent, ATP-competitive, and selective PKCβ inhibitor with IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respectively. PKCβ inhibitor 1 exhibits selectivity of more than 60-fold in favor of PKCβ2 relative to other PKC isozymes (PKCα, PKCγ, and PKCε). PKCβ inhibitor 1 Chemical Structure
  95. GC44655 PKCε Inhibitor Peptide

    Protein Kinase Cɛ Inhibitor Peptide，ɛV1-2

     PKCε Inhibitor Peptide, also called εV1-2, is a protein kinase C ε (PKCε)-derived peptide, act as a selective PKCε inhibitor, inhibits the translocation of PKCε . PKCε Inhibitor Peptide Chemical Structure
  96. GC74417 PKCθ pseudosubstrate peptide inhibitor,myristoylated TFA PKCθ pseudosubstrate peptide inhibitor, myristoylated TFA is a synthetic peptide that can be used to study the mechanism of action of PKCθ. PKCθ pseudosubstrate peptide inhibitor,myristoylated TFA Chemical Structure
  97. GC31711 PKC-IN-1 PKC-IN-1 is a potent, ATP-competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5.3 and 10.4 nM for human PKCβ and PKCα, and IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM for PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε, respectively. PKC-IN-1 Chemical Structure
  98. GC65126 PKC-iota inhibitor 1 PKC-iota inhibitor 1 (compound 19) is a protein kinase C-iota (PKC-ι ?) inhibitor with an IC50 value of 0.34 μM. PKC-iota inhibitor 1 Chemical Structure
  99. GC30200 PKC-theta inhibitor PKC-theta inhibitor is a selective PKC-θinhibitor, with an IC50 of 12 nM. PKC-theta inhibitor Chemical Structure
  100. GC70591 PKC-theta inhibitor 1 PKC-theta inhibitor 1 is the PKCθ inhibitor with an Ki value of 6 nM, inhibits IL-2 production in vivo with an IC50 of 0.19 μM. PKC-theta inhibitor 1 Chemical Structure
  101. GC67686 PKCiota-IN-2 formic PKCiota-IN-2 formic Chemical Structure

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