Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

    image loader

    Adding item(s) to cart......

Home >> Signaling Pathways >> TGF-β / Smad Signaling >> SMAD

SMAD

SMAD are intracellular proteins that transduce extracellular signals from transforming growth factor beta ligands to the nucleus where they activate downstream gene transcription.

Products for  SMAD

  1. Cat.No. Product Name Information
  2. GC41863 10,11-dehydro Curvularin

    α,β-dehydro Curvularin

     A natural mycotoxin 10,11-dehydro Curvularin Chemical Structure
  3. GN10534 Asiaticoside

    Ba 2742, NSC 36002, NSC 166062

     Asiaticoside Chemical Structure
  4. GC32250 Chebulinic acid

    Eutannin, NSC 69862

     An ellagitannin with diverse biological activities Chebulinic acid Chemical Structure
  5. GC34060 Disitertide (P144) Disitertide (P144) (P144) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide (P144) (P144) is also a PI3K inhibitor and an apoptosis inducer. Disitertide (P144) Chemical Structure
  6. GC32914 EMT inhibitor-1 EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. EMT inhibitor-1 Chemical Structure
  7. GC31650 Halofuginone (RU-19110) Halofuginone (RU-19110) (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone (RU-19110) Chemical Structure
  8. GC31950 Halofuginone hydrobromide (RU-19110 (hydrobromide)) Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromide (RU-19110 (hydrobromide)) Chemical Structure
  9. GC17523 Hydrochlorothiazide

    HCTZ, NSC 53477, SU 5879

     diuretic drug of the thiazide class Hydrochlorothiazide Chemical Structure
  10. GC15057 Kartogenin Promote differentiation of multipotent MSCs into chondrocytes Kartogenin Chemical Structure
  11. GC16580 LDN-193189

    LDN 193189;LDN193189

     ALK inhibitor,potent and selective LDN-193189 Chemical Structure
  12. GC14931 LDN193189 Hydrochloride

    LDN 193189 hydrochloride; LDN-193189 hydrochloride

     LDN193189 Hydrochloride is a selective inhibitor of the transcriptionally active morphogenetic protein (BMP) type I receptor, a family of BMP receptors that includes activin receptor-like kinases (ALK1, ALK2, ALK3, and ALK6). LDN193189 Hydrochloride inhibits ALK2 and ALK3 with IC50 values of 5nM and 30nM, respectively. LDN193189 Hydrochloride Chemical Structure
  13. GC11604 LY364947

    HTS 466284, TGFβ RI Kinase Inhibitor

    Inhibitor of TGF-β type I receptor kinase domain

     LY364947 Chemical Structure
  14. GN10378 Oxymatrine

    Matrine 1oxide

     Oxymatrine Chemical Structure
  15. GC12790 Pirfenidone

    AMR 69

     Pirfenidone (AMR69) is an orally active antifibrotic drug that attenuates the production of chemokines CCL2 and CCL12 in fibrocytes . Pirfenidone Chemical Structure
  16. GC16793 RepSox

    E 616452, RepSox, SJN 2511

     RepSox is a potent and selective inhibitor of transforming growth factor-β receptor I/activin-like kinase 5 (TGF-β-RI/ALK5) with an IC50 of 23nM. RepSox inhibits ALK5 autophosphorylation with an IC50 of 4nM. RepSox Chemical Structure
  17. GC17191 SIS3 HCl SIS3 HCl is a Smad3 inhibitor that inhibits the phosphorylation of Smad3 with an IC50 of 3 μM. SIS3 HCl Chemical Structure
  18. GC44903 SMAD3 Inhibitor, SIS3 SMAD3 Inhibitor, SIS3 is a potent and selective inhibitor of Smad3 phosphorylation. SMAD3 Inhibitor, SIS3 Chemical Structure
  19. GC19338 SRI-011381 hydrochloride An oral bioavailabile TGF-beta signaling agonist SRI-011381 hydrochloride Chemical Structure

18 Item(s)

per page

Set Descending Direction