SMAD
SMAD are intracellular proteins that transduce extracellular signals from transforming growth factor beta ligands to the nucleus where they activate downstream gene transcription.
Products for SMAD
- Cat.No. Product Name Information
- GC41863 10,11-dehydro Curvularin A natural mycotoxin
- GN10534 Asiaticoside
- GC32250 Chebulinic acid An ellagitannin with diverse biological activities
- GC34060 Disitertide (P144) Disitertide (P144) (P144) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide (P144) (P144) is also a PI3K inhibitor and an apoptosis inducer.
- GC32914 EMT inhibitor-1 EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities.
- GC31650 Halofuginone (RU-19110) Halofuginone (RU-19110) (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM.
- GC31950 Halofuginone hydrobromide (RU-19110 (hydrobromide)) Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM.
- GC17523 Hydrochlorothiazide diuretic drug of the thiazide class
- GC15057 Kartogenin Promote differentiation of multipotent MSCs into chondrocytes
- GC16580 LDN-193189 ALK inhibitor,potent and selective
- GC14931 LDN193189 Hydrochloride An inhibitor of BMP receptors ALK1, ALK2, ALK3, and ALK6
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GC11604
LY364947
Inhibitor of TGF-β type I receptor kinase domain
- GN10378 Oxymatrine
- GC12790 Pirfenidone TGF-β production inhibitor
- GC16793 RepSox A selective inhibitor of ALK5
- GC17191 SIS3 HCl SIS3HCl is a potent and selective inhibitor of Smad3 with an IC50 of 3 μM for Smad3 phosphorylation.
- GC44903 SMAD3 Inhibitor, SIS3 SMAD3 Inhibitor, SIS3 is a potent and selective inhibitor of Smad3 phosphorylation.
- GC19338 SRI-011381 hydrochloride An oral bioavailabile TGF-beta signaling agonist