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Home >> Signaling Pathways >> TGF-β / Smad Signaling >> TGF-βR1(ALK5)

TGF-βR1(ALK5)

TGF-βR1 (transforming growth factor beta receptors) are a serine/threonine protein kinase that involved in the regulation of cell cycle arrest, cell proliferation and differentiation, production of extracellular matrix, wound healing, tumorgenesis and immunosuppression etc.

Products for  TGF-βR1(ALK5)

  1. Cat.No. Product Name Information
  2. GC13927 A 77-01

    A77-01;A-77-01

     A potent ALK5 inhibitor A 77-01 Chemical Structure
  3. GC10166 A 83-01 A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50 s of 12 nM,45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively . A 83-01 Chemical Structure
  4. GC11050 ALK5 Inhibitor II (hydrochloride)

    E 616452,RepSox,SJN 2511

     ALK5 inhibitor ALK5 Inhibitor II (hydrochloride) Chemical Structure
  5. GC14298 DMH-1

    BMP Inhibitor II, DorsoMorphin Homolog 1, VU036482

     Selective BMP ALK2 receptor DMH-1 Chemical Structure
  6. GC11878 GW788388 ALK5 inhibitor,potent and selective GW788388 Chemical Structure
  7. GC15567 K02288 ALK inhibitor K02288 Chemical Structure
  8. GC17035 LDN-212854 BMP receptor inhibitor,potent and selective LDN-212854 Chemical Structure
  9. GC12363 LY2109761 TβRI/II kinase inhibitor LY2109761 Chemical Structure
  10. GC18015 LY2157299

    LY-2157299;LY 2157299

     LY2157299 is an oral and selective TGF-β receptor type I (TGF-βRI) kinase inhibitor with an IC50 value of 56nM. LY2157299 Chemical Structure
  11. GC17582 ML347

    LDN193719

     BMP receptor inhibitor,potent and selective ML347 Chemical Structure
  12. GC10421 SB-505124 hydrochloride

    SB 505124 hydrochloride;SB505124 hydrochloride

     Inhibitor of receptors ALK4, ALK5, and ALK7 SB-505124 hydrochloride Chemical Structure
  13. GC14349 SB525334

    TGF-β RI Kinase Inhibitor VIII

     (TGF-beta1) receptor inhibitor SB525334 Chemical Structure
  14. GC13904 SD-208

    TGF-β RI Kinase Inhibitor V

     A potent, selective inhibitor of TGF-βRI SD-208 Chemical Structure

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