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Home >> Signaling Pathways >> Tyrosine Kinase >> Axl

Axl

Axl is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm and takes part in the stimulation of cell proliferation.

Products for  Axl

  1. Cat.No. Product Name Information
  2. GC14214 BMS-777607 BMS-777607 is a pan-TAM inhibitor, which shows anti-tumor activity to different types of cancer. BMS-777607 Chemical Structure
  3. GC15779 Cabozantinib (XL184, BMS-907351) Cabozantinib (XL184, BMS-907351) is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035, and 1.3 nM, respectively. Cabozantinib (XL184, BMS-907351) displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3 (IC50=4.6, 5.2, 7, 14.3, and 11.3 nM, respectively). Cabozantinib (XL184, BMS-907351) shows antiangiogenic activity. Cabozantinib (XL184, BMS-907351) disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis. Cabozantinib (XL184, BMS-907351) Chemical Structure
  4. GC14241 LDC1267 TAM kinase inhibitor,highly selective LDC1267 Chemical Structure
  5. GC17618 R428 R428 (R428) is a potent and selective inhibitor of Axl with an IC50 of 14 nM. R428 Chemical Structure
  6. GC14218 TP-0903 TP-0903 (TP-0903) is a potent and selective Axl receptor tyrosine kinase inhibitor with an IC50 value of 27 nM. TP-0903 Chemical Structure
  7. GC13500 UNC2881 Mer tyrosine kinase inhibitor UNC2881 Chemical Structure

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