CSF-1R

CSF-1R is a tyrosine kinase transmembrane receptor for colony stimulating factor 1. It is a cytokine that regulates proliferation and differentiation of macrophages.

Products for CSF-1R

Cat.No. Product Name Information
GC12539 BLZ945

BLZ945
BLZ945 (BLZ945) is a potent, selective and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs.
GC17286 GW2580 CFMS kinase/CSF-1R inhibitor,selective and ATP-competitive
GC12222 Pexidartinib (PLX3397)

PLX3397

Pexidartinib(PLX3397) is an orally administered small molecule tyrosine kinase inhibitor with potent selective activity against the colony-stimulating factor 1(CSF1) receptor(IC50=20nM), KIT proto-oncogene receptor tyrosine kinase(KIT)(IC50 =10nM) and FMS-like tyrosine kinase.