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FLT3

FLT3 (FMS-like tyrosine kinase 3) is a cytokine receptor which belongs to the receptor tyrosine kinase class III and plays a role in cell survival, proliferation, and differentiation.

  1. Cat.No. Product Name Information
  2. GC11205 5'-Fluoroindirubinoxime FMS-like receptor tyrosine kinase-3 (FLT3) inhibitor
  3. GC18167 AC710

    A potent and selective PDGFR family inhibitor

  4. GC16604 Altiratinib c-MET/TIE-2/VEGFR inhibitor
  5. GC14974 AMG 925 FLT3/CDK4 inhibitor,potent and selective
  6. GC35315 AMG 925 HCl
  7. GC16391 Amuvatinib (MP-470, HPK 56)

    Tyrosine kinase inhibitor

  8. GC33362 Amuvatinib hydrochloride (MP470 hydrochloride)
  9. GC10914 AST 487 RET kinase inhibitor
  10. GC10638 AT9283 Aurora kinase/JAK inhibitor
  11. GC17959 AZD2932 inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit
  12. GC19080 BPR1J-097 BPR1J-097 is a novel potent FLT3 inhibitor with an IC50 of 11 nM.
  13. GC35544 BPR1J-097 Hydrochloride
  14. GC15779 Cabozantinib (XL184, BMS-907351) VEGFR2/Met/Ret/Kit/FLT//AXL inhibitor
  15. GC19092 CCT241736 CCT241736 is a potent and orally bioavailable dual FLT3 and Aurora kinase inhibitor, which inhibits Aurora kinases (Aurora-A Kd, 7.5 nM, IC50, 38 nM; Aurora-B Kd, 48 nM), FLT3 kinase (Kd, 6.2 nM), and FLT3 mutants including FLT3-ITD (Kd, 38 nM) and FLT3(D835Y) (Kd, 14 nM).
  16. GC33064 CG-806
  17. GC15739 CHIR-124 Chk1 inhibitor,novel and potent
  18. GC14906 Crenolanib (CP-868596) PDGFR-β inhibitor,potent and selective
  19. GC38412 Crotonoside
  20. GC14007 DCC-2036 (Rebastinib) Bcr-Abl inhibitor
  21. GC13547 Dovitinib (TKI-258, CHIR-258) Multitargeted RTK inhibitor

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