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Home >> Signaling Pathways >> Tyrosine Kinase >> Tie-2

Tie-2

Tie-2 (angiopoietin receptor) is a receptor tyrosine kinase and is capable of physiologic activation as a result of binding the angiopoietins.

Products for  Tie-2

  1. Cat.No. Product Name Information
  2. GC13598 MGCD-265 MGCD-265 is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50s of 29 nM and 10 nM, respectively. MGCD-265 has significant antitumor activity. MGCD-265 Chemical Structure
  3. GC49686 N-desmethyl Regorafenib N-oxide An active metabolite of regorafenib N-desmethyl Regorafenib N-oxide Chemical Structure
  4. GC14898 Tie2 kinase inhibitor Tie2 kinase inhibitor (compound 5) is a potent, selective Tie2 kinase inhibitor with an IC50 of 250 nM. Tie2 kinase inhibitor has anti-cancer activity. Tie2 kinase inhibitor Chemical Structure

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