Tie-2
Tie-2 (angiopoietin receptor) is a receptor tyrosine kinase and is capable of physiologic activation as a result of binding the angiopoietins.
Products for Tie-2
- Cat.No. Product Name Information
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GC13598
MGCD-265
MGCD-265 is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50s of 29 nM and 10 nM, respectively. MGCD-265 has significant antitumor activity.
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GC49686
N-desmethyl Regorafenib N-oxide
An active metabolite of regorafenib
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GC44474
NVP-AEW541 (hydrochloride)
Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis.
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GC14898
Tie2 kinase inhibitor
Tunica Interna Endothelial Cell Kinase 2 Inhibitor
Tie2 kinase inhibitor is a reversible and selective inhibitor of Tie2 with an IC50 of 250 nM.