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Tie-2

Tie-2 (angiopoietin receptor) is a receptor tyrosine kinase and is capable of physiologic activation as a result of binding the angiopoietins.

Products for  Tie-2

  1. Cat.No. Product Name Information
  2. GC13598 MGCD-265 MGCD-265 is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50s of 29 nM and 10 nM, respectively. MGCD-265 has significant antitumor activity. MGCD-265  Chemical Structure
  3. GC49686 N-desmethyl Regorafenib N-oxide An active metabolite of regorafenib N-desmethyl Regorafenib N-oxide  Chemical Structure
  4. GC44474 NVP-AEW541 (hydrochloride) Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. NVP-AEW541 (hydrochloride)  Chemical Structure
  5. GC14898 Tie2 kinase inhibitor

    Tunica Interna Endothelial Cell Kinase 2 Inhibitor

    Tie2 kinase inhibitor is a reversible and selective inhibitor of Tie2 with an IC50 of 250 nM. Tie2 kinase inhibitor  Chemical Structure

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