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Ubiquitination/ Proteasome

Products for  Ubiquitination/ Proteasome

  1. Cat.No. Product Name Information
  2. GC15605 Ezetimibe Cholesterol transport inhibitor Ezetimibe  Chemical Structure
  3. GC60159 Ezetimibe ketone Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe. Ezetimibe ketone  Chemical Structure
  4. GC36023 FAAH inhibitor 1 FAAH inhibitor 1 (Benzothiazole analog 3) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 18±8 nM. FAAH inhibitor 1  Chemical Structure
  5. GC30751 FAAH-IN-1 FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively. FAAH-IN-1  Chemical Structure
  6. GC30366 FAAH-IN-2 FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent FAAH(fatty acid amide hydrolase) inhibitor extracted from Patent WO/2008/100977A2. FAAH-IN-2  Chemical Structure
  7. GC62203 Falcarindiol Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol  Chemical Structure
  8. GC38437 Fangchinoline An alkaloid with diverse biological activities Fangchinoline  Chemical Structure
  9. GC13869 Fasudil Calcium antagonist Fasudil  Chemical Structure
  10. GC14289 Fasudil (HA-1077) HCl Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil (HA-1077) HCl is also a potent Ca2+ channel antagonist and vasodilator. Fasudil (HA-1077) HCl  Chemical Structure
  11. GC17173 Felodipine Selective L-type Ca2+ channel blocker Felodipine  Chemical Structure
  12. GC12250 Fenofibrate

    PPARα agonist

    Fenofibrate  Chemical Structure
  13. GC17143 Fenretinide A synthetic retinoic acid derivative Fenretinide  Chemical Structure
  14. GC40484 Ferulic Acid methyl ester Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. Ferulic Acid methyl ester  Chemical Structure
  15. GC10755 Fexaramine farnesoid X receptor agonist Fexaramine  Chemical Structure
  16. GC13620 FIPI

    phosholipase D (PLD) inhibitor

    FIPI  Chemical Structure
  17. GC15609 FK 866 hydrochloride NMPRTase inhibitor FK 866 hydrochloride  Chemical Structure
  18. GC31563 FK-448 Free base FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM. FK-448 Free base  Chemical Structure
  19. GC14308 FK866 (APO866) Inhibitor of nicotinamide phosphoribosyltransferase FK866 (APO866)  Chemical Structure
  20. GC16063 Flavopiridol An inhibitor of cyclin-dependent kinases Flavopiridol  Chemical Structure
  21. GC16425 Flavopiridol hydrochloride CDK inhibitor, potent and selective Flavopiridol hydrochloride  Chemical Structure
  22. GC33848 Fludrocortisone acetate (9α-Fludrocortisone acetate) Fludrocortisone acetate (9α-Fludrocortisone acetate) (9α-Fludrocortisone acetate (9α-Fludrocortisone acetate)) is a synthetic mineralocorticoid, used to control the amount of sodium and fluids in your body. Fludrocortisone acetate (9α-Fludrocortisone acetate)  Chemical Structure
  23. GC33715 Fluoxetine (LY-110140)

    Fluoxetine (LY-110140) is an orally active selective serotonin reuptake inhibitor (SSRI). Fluoxetine is a potent inhibitor of the saturated [3H]-5-HT uptake process in rat and human platelets, with IC50 values of 0.10 and 0.05 μM, respectively.

    Fluoxetine (LY-110140)  Chemical Structure
  24. GC11709 Fluoxetine HCl Serotonin reuptake inhibitor,selective Fluoxetine HCl  Chemical Structure
  25. GC10064 Flurizan A COX-inactive enantiomer of flurbiprofen Flurizan  Chemical Structure
  26. GC13535 Fluvastatin An HMG-CoA reductase inhibitor Fluvastatin  Chemical Structure
  27. GC36061 Fluvastatin D6 sodium Fluvastatin D6 sodium (XU 62-320 D6) is deuterium labeled Fluvastatin sodium. Fluvastatin D6 sodium  Chemical Structure
  28. GC15541 Fluvastatin Sodium An HMG-CoA reductase inhibitor Fluvastatin Sodium  Chemical Structure
  29. GC36063 FMK 9a FMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay. FMK 9a  Chemical Structure
  30. GC11920 Forskolin

    Forskolin is a potent adenylyl cyclase activator with IC50 of 41 nM for type I adenylyl cyclase.

    Forskolin  Chemical Structure
  31. GC32411 FR 167653 (FR 167653 sulfate) FR 167653 (FR 167653 sulfate) (FR 167653 (FR 167653 sulfate) sulfate), an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. FR 167653 (FR 167653 sulfate)  Chemical Structure
  32. GC31058 FR 167653 free base FR 167653 free base, an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. FR 167653 free base  Chemical Structure
  33. GC18000 Fulvestrant (ICI 182,780)

    Fulvestrant is a selective estrogen receptor (ER) antagonist. It binds, blocks and degrades ER, then inhibits ER-mediated transcriptional activity with an IC50 of 9.4 nM.

    Fulvestrant (ICI 182,780)  Chemical Structure
  34. GC13711 Gabexate mesylate A serine protease inhibitor Gabexate mesylate  Chemical Structure
  35. GN10137 Galangin Galangin  Chemical Structure
  36. GC12139 Gambogic Acid A xanthonoid with anticancer activity Gambogic Acid  Chemical Structure
  37. GN10109 Ganoderic Acid A Ganoderic Acid A  Chemical Structure
  38. GC10359 GANT61

    GANT61 was able to efficiently block GLI1 as well as GLI2-induced transcription, IC50 is 5 µM.

    GANT61  Chemical Structure
  39. GC32739 GCN2iB GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM. GCN2iB  Chemical Structure
  40. GC12021 GDC-0349 MTOR inhibitor GDC-0349  Chemical Structure
  41. GC10493 GDC-0449 (Vismodegib) GDC-0449 (Vismodegib)  Chemical Structure
  42. GC10816 GDC-0941 A pan inhibitor of class I PI3K isoforms GDC-0941  Chemical Structure
  43. GC16154 GDC-0941 dimethanesulfonate A pan inhibitor of class I PI3K isoforms GDC-0941 dimethanesulfonate  Chemical Structure
  44. GC60868 Gefitinib D8 Gefitinib D8 (ZD1839 D8) is a deuterium labeled Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8  Chemical Structure
  45. GC16805 Gemcitabine

    An inhibitor of DNA synthesis

    Gemcitabine  Chemical Structure
  46. GC36130 Gemcitabine elaidate A prodrug form of gemcitabine Gemcitabine elaidate  Chemical Structure
  47. GC14447 Gemcitabine HCl Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis. Gemcitabine HCl  Chemical Structure
  48. GN10116 Genipin Genipin  Chemical Structure
  49. GC14102 Genistein

    Genistein is an isoflavone belonging to the flavonoid group of compounds and is found in a number of plants.

    Genistein  Chemical Structure
  50. GN10782 Genistin Genistin  Chemical Structure
  51. GC31717 Ginkgetin A biflavonoid with diverse biological activities Ginkgetin  Chemical Structure
  52. GC36136 Ginkgolide K Ginkgolide K, isolated from Ginkgo biloba, induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway. Ginkgolide K  Chemical Structure
  53. GN10148 Ginsenoside F2 Ginsenoside F2  Chemical Structure
  54. GN10156 Ginsenoside Rb1 Ginsenoside Rb1  Chemical Structure
  55. GC32998 Ginsenoside Rh4 Ginsenoside Rh4  Chemical Structure
  56. GC33085 Glaucocalyxin B Glaucocalyxin B is an ent kaurane diterpenoid isolated from the Chinese traditional medicine Rabdosia japonica with anticancer and antitumor activity; decreases the growth of HL-60 cells with an IC50 of approximately 5.86 μM at 24 h. Glaucocalyxin B  Chemical Structure
  57. GC12356 Glibenclamide Insulin production modulator Glibenclamide  Chemical Structure
  58. GC17255 Gliotoxin An immunosuppressive mycotoxin with diverse biological effects Gliotoxin  Chemical Structure
  59. GC19169 GLPG1837 GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively. GLPG1837  Chemical Structure
  60. GC36149 GLPG2451 GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM. GLPG2451  Chemical Structure
  61. GC30263 Glucosamine (D-Glucosamine) Glucosamine (D-Glucosamine) (D-Glucosamine (D-Glucosamine)) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine (D-Glucosamine)  Chemical Structure
  62. GN10669 Glucosamine sulfate Glucosamine sulfate  Chemical Structure
  63. GC40911 Glycine-β-muricholic Acid Glycine-β-muricholic Acid, a bile acid, is a potent, sable, intestine-selective and oral bioactive farnesoid X receptor (FXR) inhibitor that may be a candidate for the treatment of metabolic disorders. Glycine-β-muricholic Acid  Chemical Structure
  64. GC47408 Glycochenodeoxycholic Acid-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Glycochenodeoxycholic Acid-d4  Chemical Structure
  65. GC36163 Glycycoumarin Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases. Glycycoumarin  Chemical Structure
  66. GC17804 GlyH-101 CFTR Inhibitor II GlyH-101  Chemical Structure
  67. GC60882 Glyphosate

    An herbicide

    Glyphosate  Chemical Structure
  68. GC41308 GPP 78 Nicotinamide phosphoribosyltransferase (Nampt) converts nicotinamide into nicotinamide mononucleotide (NMN), which is subsequently converted to NAD+ by NMN adenyltransferase. GPP 78  Chemical Structure
  69. GC10715 GSK 4112 Rev-Erbα agonist GSK 4112  Chemical Structure
  70. GC15072 GSK2126458 GSK2126458 (GSK2126458) is an orally active and highly selective inhibitor of PI3K with Kis of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM for p110α/β/δ/γ, mTORC1/2, respectively. GSK2126458 has anti-cancer activity. GSK2126458  Chemical Structure
  71. GC18049 GSK2578215A LRRK2 inhibitor GSK2578215A  Chemical Structure
  72. GC17450 GSK2606414

    A selective PERK inhibitor

    GSK2606414  Chemical Structure
  73. GC11068 GSK2656157 PERK inhibitor GSK2656157  Chemical Structure
  74. GC17534 GSK343 A selective, cell-permeable EZH2 inhibitor GSK343  Chemical Structure
  75. GC64213 GSK3494245 GSK3494245 (DDD01305143) is a potent, orally active, and selective inhibitor of the chymotrypsin-like activity of the parasite proteasome binding in a site sandwiched between the β4 and β5 subunits (IC50=0.16 μM for WT L. GSK3494245  Chemical Structure
  76. GC13696 GSK690693

    GSK690693 is an ATP-competitive, low nanomolar inhibitor of Akt kinases with IC50 values of 2, 13, and 9 nM for Akt1, 2, and 3, respectively.

    GSK690693  Chemical Structure
  77. GC17658 Guggulsterone Broad spectrum steroid receptor ligand Guggulsterone  Chemical Structure
  78. GC60891 GW406108X GW406108X is a specific Kif15 (Kinesin-12) inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X, a potent autophagy inhibitor, shows ATP competitive inhibition against ULK1 with a pIC50 of 6.37 (427 nM). GW406108X inhibits ULK1 kinase activity and blocks autophagic flux, without affecting the upstream signaling kinases mTORC1 and AMPK. GW406108X  Chemical Structure
  79. GC10975 GW4064

    GW4064, as a synthetic FXR agonist, was used for treatment of cholestatic liver diseases, metabolic syndrome and alcoholic liver disease.

    GW4064  Chemical Structure
  80. GC15318 GW501516 A selective PPARδ-agonist with anti-obesity activity GW501516  Chemical Structure
  81. GC45719 Gymnemic Acid I A triterpene glycoside Gymnemic Acid I  Chemical Structure
  82. GC19396 H 89

    A potent inhibitor of cyclic AMP-dependent protein kinase

    H 89  Chemical Structure
  83. GC10074 H 89 2HCl H 89 2HCl is a potent and selective inhibitor of protein kinase A (PKA) with an IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase. H 89 2HCl  Chemical Structure
  84. GA10942 H-D-Gln-OH H-D-Gln-OH  Chemical Structure
  85. GC19188 HA15 HA15 is a molecule that targets specifically BiP/GRP78/HSPA5. HA15  Chemical Structure
  86. GC12622 HBX 41108 Ubiquitin-specific protease (USP) 7 inhibitor HBX 41108  Chemical Structure
  87. GC14591 Hemin chloride Hemin chloride is an iron-containing porphyrin. Hemin chloride  Chemical Structure
  88. GC10829 Heparin

    injectable anticoagulant

    Heparin  Chemical Structure
  89. GC36215 Heparin Lithium salt Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII). Heparin Lithium salt  Chemical Structure
  90. GC19766 Heparin sodium salt (MW 15kDa)

    A polymer of Heparin with the molecular weight of 15kD

    Heparin sodium salt (MW 15kDa)  Chemical Structure
  91. GC17196 Hesperadin A multi-kinase inhibitor Hesperadin  Chemical Structure
  92. GN10613 Hesperidin Hesperidin  Chemical Structure
  93. GN10248 Hesperitin Hesperitin  Chemical Structure
  94. GC45639 Hexapeptide-11 (acetate) A synthetic hexapeptide Hexapeptide-11 (acetate)  Chemical Structure
  95. GC16699 HMB-Val-Ser-Leu-VE inhibitor of the trypsin-like activity of the 20S proteasome HMB-Val-Ser-Leu-VE  Chemical Structure
  96. GC63515 Hoechst 33342

    The nucleic acid stain Hoechst 33342 (Ex/Em: 350/461 nm) is frequently utilized as a cell-permeable nuclear counterstain that emits a blue fluorescence upon binding to dsDNA.

    Hoechst 33342  Chemical Structure
  97. GC10939 Hoechst 33342 trihydrochloride

    The nucleic acid stain Hoechst 33342 trihydrochloride (Ex/Em: 350/461 nm) is frequently utilized as a cell-permeable nuclear counterstain that emits a blue fluorescence upon binding to dsDNA.

    Hoechst 33342 trihydrochloride  Chemical Structure
  98. GN10664 Honokiol Honokiol  Chemical Structure
  99. GC47436 HT-2 Toxin-13C22 An internal standard for the quantification of HT-2 toxin HT-2 Toxin-13C22  Chemical Structure
  100. GC19569 Hydroquinone Hydroquinone  Chemical Structure
  101. GC12544 Hydroxychloroquine Sulfate

    Autophagy inhibitor

    Hydroxychloroquine Sulfate  Chemical Structure

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