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Home >> Signaling Pathways >> Ubiquitination/ Proteasome

Ubiquitination/ Proteasome

Products for  Ubiquitination/ Proteasome

  1. Cat.No. Product Name Information
  2. GC15890 Cilostazol

    OPC 13013, OPC 21, Pletaal, Pletal

     A PDE3A inhibitor Cilostazol Chemical Structure
  3. GN10189 Cinobufagin

    NSC 90325

     Cinobufagin Chemical Structure
  4. GC12226 Cisatracurium Besylate Neuromuscular-blocking drug Cisatracurium Besylate Chemical Structure
  5. GC14035 Citalopram hydrobromide

    Bonitrile, Lu 10-171B, Nitalapram, Prepram

     5-HT uptake inhibitor Citalopram hydrobromide Chemical Structure
  6. GC16754 Clarithromycin

    A-56268, Antibiotic A 56268, TE 031

     A macrolide antibiotic Clarithromycin Chemical Structure
  7. GC16581 Clasto-Lactacystin β-lactone

    β-Clastolactacystin; Omuralide

     A selective inhibitor of the 20S proteasome Clasto-Lactacystin β-lactone Chemical Structure
  8. GC14892 Clemastine Fumarate Selective histamine H1 receptor antagonist Clemastine Fumarate Chemical Structure
  9. GC71637 Clemastine-d5 fumarate Clemastine-d5 (fumarate) is the deuterium labeled Clemastine fumarate. Clemastine-d5 fumarate Chemical Structure
  10. GC64524 Clematichinenoside AR Clematichinenoside AR is a major active ingredient that could be extracted from the traditional Chinese herb Clematis chinensis and has potent pharmacological effects on various diseases, including atherosclerosis (AS). Clematichinenoside AR Chemical Structure
  11. GC15810 Clinofibrate

    S-8527

     HMGCR inhibitor Clinofibrate Chemical Structure
  12. GC32078 Clioquinol (Iodochlorhydroxyquin)

    Iodochlorohydroxyquin, NSC 3531, NSC 74938

     Clioquinol (Iodochlorhydroxyquin) (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol (Iodochlorhydroxyquin) Chemical Structure
  13. GC73224 CLK1-IN-3 CLK1-IN-3 (compound 10ad) is a potent and selective Clk1 inhibitor, with an IC50 of 5 nM and over 300-fold selectivity for Dyrk1A. CLK1-IN-3 Chemical Structure
  14. GC15219 Clofarabine

    Clolar, Evoltra

     Antimetabolite,inhibit DNA polymerase and ribonucleotide reductase Clofarabine Chemical Structure
  15. GC16804 Clotrimazole

    BAYB5087, NSC 257473

     antifungal compound Clotrimazole Chemical Structure
  16. GC13261 Colchicine Colchicine, an orally active alkaloid, disrupts cytoskeletal function by inhibiting the polymerization of β-tubulin into microtubules, with an IC50 of 3 nM. Colchicine Chemical Structure
  17. GC16332 Colistin Sulfate

    Polymyxin E Complex

     Cationic polypeptide antibiotic Colistin Sulfate Chemical Structure
  18. GC17519 Concanamycin A

    Antibiotic X 4357B； NSC 674620； X 4357B

     Concanamycin A is a specific inhibitor of vacuolar-type ATPase (V-ATPase) with IC50 value of 10 nM [1]. Concanamycin A Chemical Structure
  19. GN10810 Cordycepin

    3'Deoxyadenosine, NSC 63984, NSC 401022

     Cordycepin (3’-deoxyadenosine) is a nucleoside analog that inhibits polyadenylation. Cordycepin Chemical Structure
  20. GN10015 Corosolic Acid

    Glucosol, 2α-Hydroxyursolic Acid

     Corosolic Acid Chemical Structure
  21. GC32959 Corynoxine

    An indole alkaloid

     Corynoxine Chemical Structure
  22. GC52477 Corynoxine (hydrochloride) An indole alkaloid Corynoxine (hydrochloride) Chemical Structure
  23. GC32826 Corynoxine B

    Corynoxine B is an oxindole alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese); a Beclin-1-dependent autophagy inducer.

     Corynoxine B Chemical Structure
  24. GC43321 CPTH6 (hydrobromide) CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP. CPTH6 (hydrobromide) Chemical Structure
  25. GC14906 Crenolanib (CP-868596)

    CP-868596;CP 868596;CP868596

     Crenolanib (CP-868596) is a potent and selective inhibitor of wild-type and mutant isoforms of the class III receptor tyrosine kinases FLT3 and PDGFRα/β with Kds of 0.74 nM and 2.1 nM/3.2 nM, respectively. Crenolanib (CP-868596) Chemical Structure
  26. GC30360 Cresol (Cresol mixture of isomers) Cresol (Cresol mixture of isomers) Chemical Structure
  27. GC12616 Crizotinib hydrochloride

    inhibitor of the c-Met kinase and the NPM-ALK

     Crizotinib hydrochloride Chemical Structure
  28. GN10501 Cryptotanshinone Cryptotanshinone is a natural compound extracted from the roots of Salvia miltiorrhiza Bunge, exhibiting antitumor activity by inhibiting Signal Transducer and Activator of Transcription 3 (STAT3) with an IC50 value of 4.6μM. Cryptotanshinone Chemical Structure
  29. GN10535 Cucurbitacin B

    Cuc B, NSC 49451, NSC 144154

     Cucurbitacin B Chemical Structure
  30. GN10526 Cucurbitacin E

    NSC 106399, NSC 521775

     Cucurbitacin E Chemical Structure
  31. GC73383 CUR5g CUR5g is a potent autophagy inhibitor. CUR5g Chemical Structure
  32. GC14787 Curcumin

    Indian Saffron, Turmeric yellow

     A yellow pigment with diverse biological activities Curcumin Chemical Structure
  33. GC40226 Curcumin-d6 Curcumin-d6 is intended for use as an internal standard for the quantification of curcumin by GC- or LC-MS. Curcumin-d6 Chemical Structure
  34. GC14495 CX 546 AMPA receptor potentiator CX 546 Chemical Structure
  35. GC13037 CX-4945 (Silmitasertib)

    CX 4945;CX4945

     CX-4945 (Silmitasertib) (CX-4945) is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'. CX-4945 (Silmitasertib) Chemical Structure
  36. GC11325 CX-4945 sodium salt

    CX-4945 sodium salt

     CX-4945 sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'. CX-4945 sodium salt Chemical Structure
  37. GC17795 Cyclocytidine HCl

    Ancitabine hydrochloride, NSC 145668, 2,2′-O-Cyclocytidine hydrochloride

     Ancitabine (hydrochloride) is an important antileukemia drugs. Cyclocytidine HCl Chemical Structure
  38. GC38419 Cyclovirobuxine D

    CVB-D, NSC 91722

     An alkaloid with diverse biological activities Cyclovirobuxine D Chemical Structure
  39. GC43354 Cysmethynil

    Icmt Inhibitor

     Post-translational protein prenylation is a 3-step process that occurs at the C-terminus of a number of proteins involved in cell growth control and oncogenesis. Cysmethynil Chemical Structure
  40. GC33779 Cysteamine (β-Mercaptoethylamine) Cysteamine (β-Mercaptoethylamine) Chemical Structure
  41. GC13502 Cysteamine HCl

    CI-9148, β-Mercaptoethylamine

     Cysteamine HCl (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant. Cysteamine HCl Chemical Structure
  42. GC17050 CYT387

    Momelotinib

     A potent inhibitor of JAK1 and JAK2 CYT387 Chemical Structure
  43. GC16468 CYT387 sulfate salt A potent inhibitor of JAK1 and JAK2 CYT387 sulfate salt Chemical Structure
  44. GC13070 Cytarabine

    1βDArabinofuranosylcytosine, NSC 63878, NSC 287459, U19920A

     Cytarabine (Ara-C) is a cytosine analog that primarily inhibits the function of DNA polymerase to block DNA synthesis. Cytarabine Chemical Structure
  45. GC14961 Cytarabine hydrochloride DNA synthsis inhibitor Cytarabine hydrochloride Chemical Structure
  46. GC43359 Cytochalasin E

    NSC 175151

     The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. Cytochalasin E Chemical Structure
  47. GC47271 D-Pyrohomoglutamic Acid

    D-pHgu, (R)-6-Oxopiperidine-2-carboxylic Acid

     A building block D-Pyrohomoglutamic Acid Chemical Structure
  48. GC40792 D-threo Sphinganine (d18:0)

    D-threo-Dihydrosphingosine, C18 D-threo Sphinganine (d18:0)

     D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0). D-threo Sphinganine (d18:0) Chemical Structure
  49. GC13202 D4476

    Casein Kinase I Inhibitor

     Inhibitor of CK1 and ALK5 D4476 Chemical Structure
  50. GN10318 Danshensu Danshensu Chemical Structure
  51. GC34010 Danshensu (Dan shen suan A)

    Danshensu, an active ingredient of Salvia miltiorrhiza, shows wide cardiovascular benefit by activating Nrf2 signaling pathway.

     Danshensu (Dan shen suan A) Chemical Structure
  52. GC30072 Dansylcadaverine (Monodansyl cadaverine)

    Dansylcadaverine, MDC

     Dansylcadaverine (Monodansyl cadaverine) (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine (Monodansyl cadaverine) Chemical Structure
  53. GC30056 Danthron (Dantron) Danthron (Dantron) is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron (Dantron) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron (Dantron) Chemical Structure
  54. GC30054 Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) Chemical Structure
  55. GC15217 Danusertib (PHA-739358)

    PHA-739358

     A pan-Aurora kinase and Abl inhibitor Danusertib (PHA-739358) Chemical Structure
  56. GN10336 Daphnetin

    7,8-Dihydroxycoumarin, NSC 633563

     Daphnetin Chemical Structure
  57. GC12942 DAPT (GSI-IX)

    gamma-Secretase Inhibitor IX, DAPT, GSI-IX

     DAPT (GSI-IX) is an orally active γ-secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid-β (Aβ) and Aβ42 produced in human primary neuronal cultures, respectively. DAPT (GSI-IX) Chemical Structure
  58. GC15568 Dasatinib (BMS-354825)

    BMS 354825, Sprycel

     An inhibitor of Abl and Src Dasatinib (BMS-354825) Chemical Structure
  59. GC35812 Dasatinib hydrochloride A potent and dual AblWT/Src inhibitor Dasatinib hydrochloride Chemical Structure
  60. GC12828 Daunorubicin

    DNA topoisomerase II inhibitor

     Daunorubicin Chemical Structure
  61. GC10354 Daunorubicin HCl

    NDC 00824155, Ondena, RP 13057

     Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin HCl Chemical Structure
  62. GC33003 Daurisoline ((R,R)-Daurisoline)

    (-)-Daurisoline, (R,R)-Daurisoline

     Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor and also an autophagy blocker. Daurisoline ((R,R)-Daurisoline) Chemical Structure
  63. GC64607 Dazcapistat Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively (patent WO2018064119A1, compound 405). Dazcapistat Chemical Structure
  64. GC10824 DBeQ

    N,N'Dibenzylquinazoline2,4diamine, JRF 12

     P97 ATPase inhibitor DBeQ Chemical Structure
  65. GC65191 DC-LC3in-D5 DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 Chemical Structure
  66. GC19485 DC661

    A potent PPT1 inhibitor

     DC661 Chemical Structure
  67. GC70757 DCAP DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP Chemical Structure
  68. GC73892 DCC-3116 DCC-3116 is an orally active ULK1/2 inhibitor. DCC-3116 Chemical Structure
  69. GC72910 DD1 DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. DD1 Chemical Structure
  70. GC35820 DDD107498 succinate

    DDD107498 succinate; DDD-498 succinate; M5717 succinate

     DDD107498 succinate (DDD-498 succinate) is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. DDD107498 succinate Chemical Structure
  71. GC13554 Deferoxamine mesylate

    Ba 33112, DFO, DFOM, DFX, NSC 644468

    Deferoxamine mesylate is a drug that chelates iron by forming a stable complex that prevents the iron from entering into further chemical reactions, and is used for the treatment of chronic iron overload in patients with transfusion-dependent anemias.

     Deferoxamine mesylate Chemical Structure
  72. GC15484 Deguelin

    (-)cisDeguelin

     A potent antiproliferative rotenoid compound Deguelin Chemical Structure
  73. GC35832 Dehydrocorydaline chloride An alkaloid with diverse biological activities Dehydrocorydaline chloride Chemical Structure
  74. GC38528 Dehydropachymic acid Dehydropachymic acid is one of the major triterpenes isolated from Poria cocos. Dehydropachymic acid Chemical Structure
  75. GN10529 Demethoxycurcumin

    DMC

     Demethoxycurcumin Chemical Structure
  76. GC90700 Dendrogenin A

    A selective LXR modulator and ChEH inhibitor

     Dendrogenin A Chemical Structure
  77. GC38564 Deoxypodophyllotoxin

    Anthricin, (-)-Deoxypodophyllotoxin, 4-Deoxypodophyllotoxin, DPT, RD4-6266

     Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from rhizomes of Sinopodophullumhexandrum (Berberidaceae). Deoxypodophyllotoxin Chemical Structure
  78. GC70636 Desethyl Amiodarone-d4 hydrochloride Desethyl Amiodarone-d4 (hydrochloride) is the deuterium labeled Desethylamiodarone hydrochloride. Desethyl Amiodarone-d4 hydrochloride Chemical Structure
  79. GC39372 Desethyl chloroquine diphosphate Desethyl chloroquine diphosphate is a major desethyl metabolite of Chloroquine. Desethyl chloroquine diphosphate Chemical Structure
  80. GC47193 Desethyl Hydroxychloroquine-d4

    Cletoquine-d4, (±)-Desethylhydroxychloroquine-d4, DHCQ-d4

     An internal standard for the quantification of desethyl hydroxychloroquine Desethyl Hydroxychloroquine-d4 Chemical Structure
  81. GC47194 Desethylchloroquine

    N-Desethylchloroquine, NSC 13254

     An active metabolite of chloroquine Desethylchloroquine Chemical Structure
  82. GC47195 Desethylchloroquine-d4

    N-Desethylchloroquine-d4

     An internal standard for the quantification of desethylchloroquine Desethylchloroquine-d4 Chemical Structure
  83. GC70755 Desfluoro-ezetimibe Desfluoro-ezetimibe is a desfluoro impurity of Ezetimibe. Desfluoro-ezetimibe Chemical Structure
  84. GC64136 Desmethyl Naproxen-d3 Desmethyl Naproxen-d3 is deuterium labeled Desmethyl Naproxen. Desmethyl Naproxen-d3 Chemical Structure
  85. GC40775 Dexamethasone

    MK-125, NSC 34521

    Dexamethasone, as one member of the glucocorticoid family, can protect against arthritis-related changes in cartilage structure and function, including matrix loss, inflammation and cartilage viability.

     Dexamethasone Chemical Structure
  86. GC14667 Dexamethasone (DHAP) Glucocorticoidan;anti-inflammatory Dexamethasone (DHAP) Chemical Structure
  87. GC11237 Dexamethasone acetate

    NSC 39471

    IL Receptor modulator

     Dexamethasone acetate Chemical Structure
  88. GC10750 Dexmedetomidine HCl

    Dex, Precedex

     Dexmedetomidine HCl ((+)-Medetomidine hydrochloride) is a potent, selective and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. Dexmedetomidine HCl Chemical Structure
  89. GC11598 Diazoxide

    NSC 64198, NSC 76130, SRG 95213

    positive allosteric modulator of the AMPA and kainate receptors

     Diazoxide Chemical Structure
  90. GC15578 Dienogest

    STS 557

     Orally active synthetic progesterone Dienogest Chemical Structure
  91. GN10056 Dihydroartemisinin

    DHQHS 2, Dihydroqinghaosu

     Dihydroartemisinin (DHA) is an active metabolite of artemisinin and its derivatives (ARTs) and is an effective drug widely used in the clinic to treat malaria. Dihydroartemisinin Chemical Structure
  92. GC16747 Dihydroeponemycin

    Dihydroeponemycin,uk101

     Dihydroeponemycin Chemical Structure
  93. GN10583 Dihydromyricetin

    (+)-Dihydromyricetin

     Dihydromyricetin is a natural flavanonol isolated from A. grossedentata and H. dulcis that has antioxidant, antiproliferative, anti-apoptotic, and anti-alcohol intoxication properties. Dihydromyricetin Chemical Structure
  94. GC31697 Dilmapimod (SB-681323) Dilmapimod (SB-681323) (SB-681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. Dilmapimod (SB-681323) Chemical Structure
  95. GC49016 Dimethyl 2-ketoglutarate

    2-KG dimethyl ester, Dimethyl α-ketoglutarate, Dimethyl 2-oxoglutarate

     An esterified form of α-ketoglutarate Dimethyl 2-ketoglutarate Chemical Structure
  96. GC74090 Dimethyl fumarate-d2 Dimetl fumarate-d2 is the deuterium labeled Dimetl fumarate. Dimethyl fumarate-d2 Chemical Structure
  97. GN10284 Dioscin

    Collettiside III

     Dioscin Chemical Structure
  98. GC38408 Diosgenin glucoside

    Diosgenin 3-O-β-D-Glucopyranoside, Diosgenin Glucoside, Diosgenyl β-D-Glucopyranoside

     Diosgenin glucoside Chemical Structure
  99. GC15212 Divalproex Sodium Valproic acid (VPA) sodium (2:1) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Divalproex Sodium Chemical Structure
  100. GC14298 DMH-1

    BMP Inhibitor II, DorsoMorphin Homolog 1, VU036482

     Selective BMP ALK2 receptor DMH-1 Chemical Structure
  101. GC16973 DMOG

    Dimethyloxallyl Glycine

     DMOG(dihydroxyalanine) is an antagonist of α-ketoglutarate cofactor and an inhibitor of HIF-proline hydroxylase, leading to the stability and accumulation of HIF-1α protein in the nucleus. DMOG Chemical Structure

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