Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

    image loader

    Adding item(s) to cart......

Home >> Signaling Pathways >> Ubiquitination/ Proteasome

Ubiquitination/ Proteasome

Products for  Ubiquitination/ Proteasome

  1. Cat.No. Product Name Information
  2. GC17243 Dorsomorphin (Compound C)

    Compound C

     Dorsomorphin (Compound C) is an agent that used as a cell-permeable AMPK inhibitor. Dorsomorphin (Compound C) Chemical Structure
  3. GC12560 Dorsomorphin (Compound C) 2HCl

    BML-275 2HCl,Compound C 2HCl

     IC50: Dorsomorphin inhibited BMP4-induced phosphorylation of BMP-responsive SMADs in a dose-dependent manner (half maximal inhibitory concentration (IC50) =0.47 mM). Dorsomorphin (Compound C) 2HCl Chemical Structure
  4. GC71260 Dox-btn2 Dox-btn2 is a biotinylated derivative of Doxorubicin , with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 Chemical Structure
  5. GC13443 Doxazosin Mesylate

    UK 33274-27

     α1-adrenergic receptor antagonist Doxazosin Mesylate Chemical Structure
  6. GC16994 Doxorubicin

    Hydroxydaunorubicin

    Doxorubicin(DOX), also known as adriamycin, is a compound of the anthracycline class that has the broadest spectrum of activity.

     Doxorubicin Chemical Structure
  7. GC17567 Doxorubicin (Adriamycin) HCl

    DOX

     Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin (Adriamycin) HCl Chemical Structure
  8. GC16073 Dronedarone An antiarrhythmic agent Dronedarone Chemical Structure
  9. GC12234 Dronedarone HCl

    SR33589

     Dronedarone HCl is a non-iodinated amiodarone derivative that inhibits Na+, K+ and Ca2+ currents. Dronedarone HCl Chemical Structure
  10. GC17125 DUBs-IN-2 DUBs-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 μM for USP8. DUBs-IN-2 Chemical Structure
  11. GC10356 DUBs-IN-3 DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8. DUBs-IN-3 Chemical Structure
  12. GC10395 Dynasore Dynasore, as a GTPase inhibitor, can rapidly and reversibly inhibit dynamin activity, which prevents endocytosis. Dynasore Chemical Structure
  13. GC13787 E 64d

    Aloxistatin, E64c ethyl ester, EP 453, EST, Loxistatin, NSC 694281

     E 64d is a cell-permeable, irreversible, broad-spectrum cysteine protease inhibitor with platelet aggregation inhibitory activity. E 64d Chemical Structure
  14. GC13418 E-64 E-64 is a potent and irreversible inhibitor of cysteine proteases with an IC50 of 9nM for papain. E-64 Chemical Structure
  15. GC39305 EACC EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC Chemical Structure
  16. GC10331 Ebselen Ebselen is a selenoorganic compound with glutathione peroxidase-like activity and is an anti-inflammatory and antioxidant agent. Ebselen is an inhibitor of inositol monophosphatase (IMPase) with an IC50 of 1.5μM. Ebselen Chemical Structure
  17. GN10564 Ecdysterone

    Ecdysterone, Isoinokosterone

     Ecdysterone is a naturally occurring ecdysone that controls molting (feathering) and metamorphosis in arthropods. Ecdysterone Chemical Structure
  18. GC12389 Efavirenz

    DMP 266, EFV, L-743,726

     Reverse transcriptase inhibitor Efavirenz Chemical Structure
  19. GC35969 eIF4A3-IN-1 eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD. eIF4A3-IN-1 Chemical Structure
  20. GC65540 eIF4A3-IN-2 eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM. eIF4A3-IN-2 Chemical Structure
  21. GC47284 Elaidic Acid-d17

    C18:1(9E)-d17, 9(E)-Oleic Acid-d17, trans-Oleic Acid-d17

     A neuropeptide with diverse biological activities Elaidic Acid-d17 Chemical Structure
  22. GC12846 Elaiophylin

    AzalomycinB, Gopalamicin, Salbomycin

     Macrodiolide antibiotic Elaiophylin Chemical Structure
  23. GC10466 EMD-1214063 EMD-1214063 (Tepotinib, MSC2156119J) is a novel potent and highly selective reversible, ATP-competitive small molecule c-Met inhibitor . EMD-1214063 Chemical Structure
  24. GC43599 Emetine (hydrochloride) An anti-protozoal drug used for intestinal and tissue amoebiasis Emetine (hydrochloride) Chemical Structure
  25. GC32048 Emetine dihydrochloride hydrate Emetine dihydrochloride hydrate is an antigen parasite drug that can be used for the treatment of intestinal and tissue amoebic diseases. Emetine dihydrochloride hydrate Chemical Structure
  26. GC16044 Emodin

    Archin, Frangulic Acid, NSC 408120, NSC 622947, Schuttgelb

     Natural CK2 inhibitor and ER agonist Emodin Chemical Structure
  27. GC49124 EN219 EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination. EN219 Chemical Structure
  28. GC35982 EN6 An activator of autophagy EN6 Chemical Structure
  29. GC15493 Enalaprilat Dihydrate angiotensin-converting enzyme (ACE) inhibitor Enalaprilat Dihydrate Chemical Structure
  30. GC11625 Entinostat (MS-275,SNDX-275)

    Entinostat, SNDX 275

     A histone deacetylase inhibitor Entinostat (MS-275,SNDX-275) Chemical Structure
  31. GC14476 Entrectinib

    NMS-E628, RXDX-101

     Orally active inhibitor of ALK kinase Entrectinib Chemical Structure
  32. GC72974 Entrectinib-d8

    NMS-E628-d8; RXDX-101-d8

     Entrectinib-d8 (NMS-E628-d8; RXDX-101-d8) is a deuterated version of Entrectinib. Entrectinib-d8 Chemical Structure
  33. GC11499 Enzastaurin (LY317615)

    LY317615

     Enzastaurin (LY317615) (LY317615) is a potent and selective PKCβ inhibitor with an IC50 of 6 nM, showing 6- to 20-fold selectivity over PKCα, PKCγ and PKCε. Enzastaurin (LY317615) Chemical Structure
  34. GC35998 Episilvestrol Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia silvestris, and is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol Chemical Structure
  35. GC12494 Epoxomicin

    BU 4061T

     Epoxomicin is a selective proteasome inhibitor that effectively inhibits the chymotrypsin-like (CH-L) activity of the 20S proteasome, with an IC50 of approximately 40-80nM. Epoxomicin Chemical Structure
  36. GC10627 Erlotinib

    NSC 718781

     Erlotinib is a potent and orally bioavailable epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with an IC50 value of 2 nM. Erlotinib Chemical Structure
  37. GC36003 Erlotinib mesylate EGFR inhibitor Erlotinib mesylate Chemical Structure
  38. GC47303 Erlotinib-d6 (hydrochloride) An internal standard for the quantification of erlotinib Erlotinib-d6 (hydrochloride) Chemical Structure
  39. GC10326 Erythromycin Ethylsuccinate Macrolide antibiotic Erythromycin Ethylsuccinate Chemical Structure
  40. GC14968 Esmolol HCl

    ASL 8052

     Esmolol HCl is a beta adrenergic receptor blocker. Esmolol HCl Chemical Structure
  41. GC13022 Esomeprazole Magnesium trihydrate An H+/K+-ATPase inhibitor Esomeprazole Magnesium trihydrate Chemical Structure
  42. GC61669 Ethyl 3,4-dihydroxybenzoate Ethyl 3,4-dihydroxybenzoate (Ethyl protocatechuate), an antioxidant, is a prolyl-hydroxylase inhibitor found in the testa of peanut seeds. Ethyl 3,4-dihydroxybenzoate Chemical Structure
  43. GC15617 Etoposide

    VP-16; VP-16-213

     Etoposide (VP-16) is a nonspecific inhibitor of topoisomerase II with an IC50 value of 59.2μM. Etoposide Chemical Structure
  44. GC60826 Etoposide phosphate Etoposide phosphate (BMY-40481) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor?to prevent re-ligation of DNA strands. Etoposide phosphate Chemical Structure
  45. GN10511 Eupatilin

    NSC 122413

     Eupatilin Chemical Structure
  46. GC13601 Everolimus (RAD001)

    RAD001

     Everolimus (RAD001) is an orally active derivative of rapamycin that inhibits the Ser/Thr kinase, mTOR (mammalian target of rapamycin). Everolimus (RAD001) Chemical Structure
  47. GC15605 Ezetimibe

    Ezetrol, SCH 58235

     Cholesterol transport inhibitor Ezetimibe Chemical Structure
  48. GC60159 Ezetimibe ketone Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe. Ezetimibe ketone Chemical Structure
  49. GC36023 FAAH inhibitor 1

    Benzothiazole analog 3

     FAAH inhibitor 1 (Benzothiazole analog 3) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 18±8 nM. FAAH inhibitor 1 Chemical Structure
  50. GC30751 FAAH-IN-1 FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively. FAAH-IN-1 Chemical Structure
  51. GC30366 FAAH-IN-2 FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent FAAH(fatty acid amide hydrolase) inhibitor extracted from Patent WO/2008/100977A2. FAAH-IN-2 Chemical Structure
  52. GC62203 Falcarindiol

    Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells.

     Falcarindiol Chemical Structure
  53. GC38437 Fangchinoline

    7-O-Demethyltetrandrine, Hanfangchin B, NSC 77036

     An alkaloid with diverse biological activities Fangchinoline Chemical Structure
  54. GC13869 Fasudil Fasudil (HA-1077; AT877) is a non-specific RhoA/ROCK inhibitor with a Ki of 0.33μM and an IC50 of 0.158μM for ROCK1, and IC50 of 4.58μM, 12.30μM, and 1.650μM for ROCK2, PKA, PKC, and PKG, respectively. Fasudil Chemical Structure
  55. GC14289 Fasudil (HA-1077) HCl Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil (HA-1077) HCl is also a potent Ca2+ channel antagonist and vasodilator. Fasudil (HA-1077) HCl Chemical Structure
  56. GC73629 FB49 FB49 is a highly selective inhibitor of Bcl-2-associated athanogene 3 (BAG3), with the Ki of 45 μM. FB49 Chemical Structure
  57. GC73307 FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 Chemical Structure
  58. GC91612 FDW028 FDW028 is an inhibitor of fucosyltransferase 8 (FUC8). FDW028 Chemical Structure
  59. GC17173 Felodipine

    H 154/82

     Selective L-type Ca2+ channel blocker Felodipine Chemical Structure
  60. GC71638 Felodipine-d3 Felodipine-d3 is the deuterium labeled Felodipine. Felodipine-d3 Chemical Structure
  61. GC12250 Fenofibrate

    PPARα agonist

     Fenofibrate Chemical Structure
  62. GC17143 Fenretinide

    4-HPR, 4-Hydroxy(phenyl)retinamide, MK-4016, Retinoic Acid p-hydroxyphenylamide, Ro 22-4667

     A synthetic retinoic acid derivative Fenretinide Chemical Structure
  63. GC91060 Ferritin PROTAC DeFer-2

    A PROTAC that drives ferritin degradation

     Ferritin PROTAC DeFer-2 Chemical Structure
  64. GC40484 Ferulic Acid methyl ester

    Methyl Ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate

     Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. Ferulic Acid methyl ester Chemical Structure
  65. GC10755 Fexaramine farnesoid X receptor agonist Fexaramine Chemical Structure
  66. GC13620 FIPI

    5Fluoro2Indolyl desChlorohalopemide

    phosholipase D (PLD) inhibitor

     FIPI Chemical Structure
  67. GC70568 FiVe1 FiVe1 is a potent vimentin (VIM; the intermediate filament and mesenchymal marker) inhibitor. FiVe1 Chemical Structure
  68. GC15609 FK 866 hydrochloride NMPRTase inhibitor FK 866 hydrochloride Chemical Structure
  69. GC31563 FK-448 Free base FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM. FK-448 Free base Chemical Structure
  70. GC14308 FK866 (APO866)

    K 22.175

    FK866 (APO866) is an inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase).

     FK866 (APO866) Chemical Structure
  71. GC16063 Flavopiridol

    Alvocidib, HL 275, HMR 1275, L-868,275

     An inhibitor of cyclin-dependent kinases Flavopiridol Chemical Structure
  72. GC16425 Flavopiridol hydrochloride

    Alvocidib, HL 275, HMR 1275, L868,275

     CDK inhibitor, potent and selective Flavopiridol hydrochloride Chemical Structure
  73. GC33848 Fludrocortisone acetate (9α-Fludrocortisone acetate)

    9α-fluoro Hydrocortisone Acetate, NSC 15186, U 4845

     Fludrocortisone acetate (9α-Fludrocortisone acetate) (9α-Fludrocortisone acetate (9α-Fludrocortisone acetate)) is a synthetic mineralocorticoid, used to control the amount of sodium and fluids in your body. Fludrocortisone acetate (9α-Fludrocortisone acetate) Chemical Structure
  74. GC33715 Fluoxetine (LY-110140) Fluoxetine (LY-110140) is an orally active, selective serotonin reuptake inhibitor (SSRI) commonly used to treat a variety of psychiatric disorders such as depression, obsessive-compulsive disorder, and panic disorder. Fluoxetine (LY-110140) Chemical Structure
  75. GC11709 Fluoxetine HCl

    LY110140

     Serotonin reuptake inhibitor,selective Fluoxetine HCl Chemical Structure
  76. GC10064 Flurizan

    E7869, Flurizan, Tarenflurbil

     A COX-inactive enantiomer of flurbiprofen Flurizan Chemical Structure
  77. GC13535 Fluvastatin

    NSC 758896

     An HMG-CoA reductase inhibitor Fluvastatin Chemical Structure
  78. GC36061 Fluvastatin D6 sodium Fluvastatin D6 sodium (XU 62-320 D6) is deuterium labeled Fluvastatin sodium. Fluvastatin D6 sodium Chemical Structure
  79. GC15541 Fluvastatin Sodium An HMG-CoA reductase inhibitor Fluvastatin Sodium Chemical Structure
  80. GC36063 FMK 9a FMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay. FMK 9a Chemical Structure
  81. GC69128 Forigerimod TFA

    IPP-201101 TFA

    Forigerimod TFA (IPP-201101 TFA) is a CD4 T cell regulator. Forigerimod TFA is a 21 amino acid fragment of U1 small nuclear ribonucleoprotein 70 kDa, phosphorylated at the Ser140 site. Forigerimod TFA can effectively inhibit autophagy. Forigerimod TFA can be used for research on autoimmune diseases such as systemic lupus erythematosus (SLE).

     Forigerimod TFA Chemical Structure
  82. GC11920 Forskolin

    Coleonol, HL 362, L 751362B, NSC 357088, NSC 375489

     Forskolin is a potent adenylyl cyclase activator with IC50 of 41 nM for type I adenylyl cyclase. Forskolin Chemical Structure
  83. GC32411 FR 167653 (FR 167653 sulfate)

    FR 167653 sulfate

     FR 167653 (FR 167653 sulfate) (FR 167653 (FR 167653 sulfate) sulfate), an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. FR 167653 (FR 167653 sulfate) Chemical Structure
  84. GC31058 FR 167653 free base FR 167653 free base, an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. FR 167653 free base Chemical Structure
  85. GC18000 Fulvestrant (ICI 182,780)

    ICI 182780

     Fulvestrant is a selective estrogen receptor (ER) antagonist. It binds, blocks and degrades estrogen receptor, then inhibits estrogen receptor(ER)-mediated transcriptional activity with an IC50 of 9.4 nM . Fulvestrant (ICI 182,780) Chemical Structure
  86. GC73961 Fumagilin-105 Fumagilin-105 is an autophagy targeting chimera (AUTOTAC) that induces p62 self-oligomerization with DC50 values of 0.7 μM for MetAP2 in HEK293 cells. Fumagilin-105 Chemical Structure
  87. GC90077 Furin Inhibitor I (trifluoroacetate salt)

    A proprotein convertase inhibitor

     Furin Inhibitor I (trifluoroacetate salt) Chemical Structure
  88. GC13711 Gabexate mesylate A serine protease inhibitor Gabexate mesylate Chemical Structure
  89. GN10137 Galangin

    NSC 407229, 3,5,7-Trihydroxyflavone

     Galangin Chemical Structure
  90. GC12139 Gambogic Acid

    GA, β-Guttiferin

     Gambogic Acid A cell-permeable caspase activator and apoptosis inducer commonly used in studies of breast, lung, and liver cancers. Gambogic Acid Chemical Structure
  91. GN10109 Ganoderic Acid A Ganoderic Acid A Chemical Structure
  92. GC10359 GANT61

    NSC 136476

     GANT61 was able to efficiently block GLI1 as well as GLI2-induced transcription, IC50 is 5 µM. GANT61 Chemical Structure
  93. GC32739 GCN2iB GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM. GCN2iB Chemical Structure
  94. GC12021 GDC-0349 MTOR inhibitor GDC-0349 Chemical Structure
  95. GC10493 GDC-0449 (Vismodegib) GDC-0449 (Vismodegib) Chemical Structure
  96. GC10816 GDC-0941

    GDC-0941

     A pan inhibitor of class I PI3K isoforms GDC-0941 Chemical Structure
  97. GC16154 GDC-0941 dimethanesulfonate

    GDC-0941 (2 MeSO3H salt);GDC0941 dimethanesulfonate;GDC-0941;GDC0941;GDC 0941

     A pan inhibitor of class I PI3K isoforms GDC-0941 dimethanesulfonate Chemical Structure
  98. GC60868 Gefitinib D8 Gefitinib D8 (ZD1839 D8) is a deuterium labeled Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 Chemical Structure
  99. GC16805 Gemcitabine

    DDFC, LY 188011, NSC 613327

    An inhibitor of DNA synthesis

     Gemcitabine Chemical Structure
  100. GC36130 Gemcitabine elaidate

    CP 4126

     A prodrug form of gemcitabine Gemcitabine elaidate Chemical Structure
  101. GC14447 Gemcitabine HCl Gemcitabine HCl is a chemically synthesized deoxycytidine derivative and a DNA synthesis inhibitor that can inhibit human serum Paraoxonase 1（PON1） activity in vitro with an IC50 value of 26.610mM. In addition, Gemcitabine HCl can also be used to treat cancers such as breast cancer, bladder cancer and pancreatic cancer. Gemcitabine HCl Chemical Structure

Items 401 to 500 of 1279 total

per page
  2. 3
  3. 4
  4. 5
  5. 6
  6. 7

Set Descending Direction