E3 Ligase
E3 ligases perform the last step in the ubiquitination cascade. They transfer the ubiquitin from the active site cysteine of E2 enzyme to the substrate lysine or N terminus. The loss of function or mis-targeting of the E3 ligases are associated with various cancer types.
Products for E3 Ligase
- Cat.No. Product Name Information
- GC25019 5-amino-2,4-dimethylpyridine (5A-DMP)
- GC50234 N106 Activator of SUMO-activating enzyme, E1 ligase
- GC44291 NAB 2 NAB 2 is an inhibitor of α-synuclein-induced toxicity.
- GC15017 NSC 624206 Ubiquitin-activating enzyme (E1) inhibitor
- GC10940 PRT 4165 Bmi1/Ring1A-mediated ubiquitination inhibitor
- GC15492 SMER 3 yeast SCF family E3 ubiquitin ligase (SCFMet30) inhibitor
- GC11869 SZL P1-41 Skp2 inhibitor