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Fungal

An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host. Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.

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  1. Cat.No. Product Name Information
  2. GC41501 α-Terpinene α-Terpinene is a terpenoid that has been found in Cannabis and has diverse biological activities, including acaricidal, antiprotozoal, and antioxidant properties. α-Terpinene  Chemical Structure
  3. GC66340 β-Amyrone β-Amyrone (β-Amyron) is a triterpene compound which has anti-inflammatory activity through inhibiting the expression of COX-2. β-Amyrone has antifungal activity , as well as antiviral activity against Chikungunya virus. β-Amyrone also inhibits α-glucosidase and acetylcholinesterase (AChE) activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity. β-Amyrone  Chemical Structure
  4. GC41503 γ-Terpinene γ-Terpinene is a monoterpene that has been found in various plants, including C. γ-Terpinene  Chemical Structure
  5. GC12404 (+)-Ketoconazole Potent inhibitor of cytochrome P450c17 (+)-Ketoconazole  Chemical Structure
  6. GC34950 (-)-Ketoconazole (-)-Ketoconazole ((-)-R 41400) is one of the enantiomer of Ketoconazole. (-)-Ketoconazole  Chemical Structure
  7. GC34946 (-​)​-Maackiain (-)-Maackiain is a pterocarpan phytoalexin produced from Red clover (Trifolium pretense L. (-​)​-Maackiain  Chemical Structure
  8. GC62733 (E)-Coniferin (E)-Coniferin is the isomer of Coniferin. (E)-Coniferin  Chemical Structure
  9. GC38725 (S,S)-Valifenalate (S,S)-Valifenalate ((S,S)-IR5885) is an acylamino acid fungicide and is used to control a wide range of fungi belonging to the class of Oomycetes. (S,S)-Valifenalate  Chemical Structure
  10. GC60428 (Z)-Lanoconazole (Z)-Lanoconazole is the Z configuration of Lanoconazole. (Z)-Lanoconazole  Chemical Structure
  11. GC62760 1-Dodecylimidazole 1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity. 1-Dodecylimidazole  Chemical Structure
  12. GC35068 1-Monomyristin A monoacylglycerol 1-Monomyristin  Chemical Structure
  13. GC30216 10-Undecenoic acid (Undecylenic acid) 10-Undecenoic acid (Undecylenic acid) was used as a starting reagent in the syntheses of Pheromone (11Z)-hexadecenal. 10-Undecenoic acid (Undecylenic acid)  Chemical Structure
  14. GC30800 10-Undecenoic acid zinc salt (Zinc undecylenate) 10-Undecenoic acid zinc salt (Zinc undecylenate) is a natural or synthetic fungistatic fatty acid, is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions. 10-Undecenoic acid zinc salt (Zinc undecylenate)  Chemical Structure
  15. GC32375 2,3-Dimethoxybenzaldehyde (o-Veratraldehyde) 2,3-Dimethoxybenzaldehyde (o-Veratraldehyde) (o-Veratraldehyde) is a benzaldehyde analog, with high antifungal activity (MIC=2.5 mM) 2,3-Dimethoxybenzaldehyde (o-Veratraldehyde) (o-Veratraldehyde) could be used for the synthesis of berberine. 2,3-Dimethoxybenzaldehyde (o-Veratraldehyde)  Chemical Structure
  16. GC32389 2,4,6-Tribromophenyl caproate 2,4,6-Tribromophenyl caproate (2,4,6-tribromophenyl caproic acid ester) is an anti-fungal agent. 2,4,6-Tribromophenyl caproate  Chemical Structure
  17. GC61899 2-Methoxybenzaldehyde 2-Methoxybenzaldehyde (o-Anisaldehyde), isolated from cinnamon essential oil (CEO), exists antibacterial and antifungal activity. 2-Methoxybenzaldehyde  Chemical Structure
  18. GC61673 3,5-Di-tert-butylphenol 3,5-Di-tert-butylphenol is an volatile organic compound with anti-biofilm and antifungal activities. 3,5-Di-tert-butylphenol  Chemical Structure
  19. GC39687 3,5-Dimethoxybenzoic acid 3,5-Dimethoxybenzoic acid, isolated from Melia azedarach L. 3,5-Dimethoxybenzoic acid  Chemical Structure
  20. GC32943 3-(Methylthio)propionic acid (3-Methylsulfanylpropionic acid) 3-(Methylthio)propionic acid (3-Methylsulfanylpropionic acid) is an intermediate in the methionine metabolism. 3-(Methylthio)propionic acid (3-Methylsulfanylpropionic acid)  Chemical Structure
  21. GC48518 3-Oxobetulin A pentacyclic triterpenoid with diverse biological activities 3-Oxobetulin  Chemical Structure
  22. GC33976 4',7-Dimethoxyisoflavone (Dimethoxydaidzein) 4',7-Dimethoxyisoflavone (Dimethoxydaidzein) is isolated from the leaves of Albizzia lebbeck, which shows antifungal activity. 4',7-Dimethoxyisoflavone (Dimethoxydaidzein)  Chemical Structure
  23. GC33949 4-Chlorosalicylic acid 4-Chlorosalicylic acid is a pharmaceutical intermediate. 4-Chlorosalicylic acid  Chemical Structure
  24. GC61686 4-Isopropylbenzoic acid 4-Isopropylbenzoic acid, an aromatic monoterpenoid, is isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid  Chemical Structure
  25. GC61678 4-Methylcinnamic acid 4-Methylcinnamic acid, a Cinnamic acid analog, can be used as a intervention catalyst for overcoming antifungal tolerance. 4-Methylcinnamic acid  Chemical Structure
  26. GC42484 5,6-dihydroxy Indole 5,6-dihydroxy Indole is an intermediate in melanogenesis. 5,6-dihydroxy Indole  Chemical Structure
  27. GC35153 5,7,3',4'-Tetramethoxyflavone 5,7,3',4'-Tetramethoxyflavone, one of the major polymethoxyflavones (PMFs) isolated from M. 5,7,3',4'-Tetramethoxyflavone  Chemical Structure
  28. GC42492 5-bromo-5-nitro-1,3-Dioxane 5-bromo-5-nitro-1,3-Dioxane is an antimicrobial compound that is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. 5-bromo-5-nitro-1,3-Dioxane  Chemical Structure
  29. GC39589 5-Dehydroepisterol 5-Dehydroepisterol is an episterol derivative and an?intermediate?in?steroid biosynthesis. 5-Dehydroepisterol  Chemical Structure
  30. GN10111 5-hydroxymethyl-2-furaldehyde 5-hydroxymethyl-2-furaldehyde  Chemical Structure
  31. GC62533 6-Chloro-7-deazapurine-β-D-riboside Chloro-7-deazapurine-β-D-riboside is a nucleoside derivative and has antifungal activity. 6-Chloro-7-deazapurine-β-D-riboside  Chemical Structure
  32. GC60034 7-O-Demethyl rapamycin

    7-O-Demethyl rapamycin, a derivative of Rapamycin, has antifungal activity and immunosuppressant properties.

    7-O-Demethyl rapamycin  Chemical Structure
  33. GC35196 7-Prenyloxycoumarin 7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense. 7-Prenyloxycoumarin  Chemical Structure
  34. GC35232 Acetyllovastatin Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Acetyllovastatin  Chemical Structure
  35. GC60566 Aegeline Aegeline, a main alkaloid, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast. Aegeline  Chemical Structure
  36. GC32379 Aliconazole Aliconazole is an antifungal imidazole derivative. Aliconazole  Chemical Structure
  37. GC35300 Aloin(mixture of A&B) Aloin (mixture of A&B) is anthraquinone derivative isolated from Aloe vera. Aloin(mixture of A&B)  Chemical Structure
  38. GC35306 alpha-Mangostin alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. alpha-Mangostin  Chemical Structure
  39. GN10484 Amentoflavone Amentoflavone  Chemical Structure
  40. GC18131 Aminothiazole Thyroid inhibitor Aminothiazole  Chemical Structure
  41. GC15052 Amorolfine HCl Amorolfine (Ro 14-4767/002) hydrochloride is a potent anti-fungal agent. Amorolfine HCl  Chemical Structure
  42. GC14092 Amphotericin B Amphipathic polyene antibiotic Amphotericin B  Chemical Structure
  43. GC60047 Amphotericin B methyl ester Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester  Chemical Structure
  44. GC15026 AN-2690 A broad spectrum antifungal agent AN-2690  Chemical Structure
  45. GC32324 AN2718 A broad-spectrum antifungal AN2718  Chemical Structure
  46. GC12754 Anidulafungin

    Antifungal drug

    Anidulafungin  Chemical Structure
  47. GC32219 Antifungal agent 1 Antifungal agent 1 is a potent antifungal agent. Antifungal agent 1  Chemical Structure
  48. GC64848 APX2039 APX2039 is an orally active and potent inhibitor of the fungal Gwt1 enzyme. APX2039  Chemical Structure
  49. GC62290 Ascr#18 Ascr#18, an ascaroside, is a hormone of nematodes. Ascr#18  Chemical Structure
  50. GC62854 Aureobasidin A Aureobasidin A (Basifungin), a cyclic depsipetide, is an antifungal antibiotic. Aureobasidin A  Chemical Structure
  51. GC46904 Azoxystrobin A broad-spectrum fungicide Azoxystrobin  Chemical Structure
  52. GC32308 Bactenecin (Bactenecin, bovine) Bactenecin (Bactenecin, bovine) (Bactenecin (Bactenecin, bovine), bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin (Bactenecin, bovine)  Chemical Structure
  53. GC18297 Bafilomycin B1 The bafilomycins are fungal plecomacrolide antibiotics with a 16-membered lactone ring. Bafilomycin B1  Chemical Structure
  54. GC39347 Benzimidazole Benzimidazole  Chemical Structure
  55. GC12797 Benzoic Acid Organic aromatic monocarboxylic acid Benzoic Acid  Chemical Structure
  56. GC65332 Benzoic acid-13C6 Benzoic acid-13C6  Chemical Structure
  57. GN10539 Bergenin Bergenin  Chemical Structure
  58. GC17752 Bifonazole imidazole antifungal drug Bifonazole  Chemical Structure
  59. GC45391 Bikaverin   Bikaverin  Chemical Structure
  60. GC25181 Butenafine Butenafine is a synthetic benzylamine antifungal agent. Butenafine  Chemical Structure
  61. GC13207 Butenafine HCl Butenafine HCl (KP363 Hydrochloride) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase. Butenafine HCl  Chemical Structure
  62. GC25182 Butoconazole Butoconazole is an imidazole antifungal used in gynecology. Butoconazole  Chemical Structure
  63. GC12984 Butoconazole nitrate Antifungal agent Butoconazole nitrate  Chemical Structure
  64. GC30960 Caerulomycin A (Cerulomycin) Caerulomycin A (Cerulomycin) (Cerulomycin; Caerulomycin), an antifungal compound, induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Caerulomycin A (Cerulomycin)  Chemical Structure
  65. GC60668 Calcimycin hemimagnesium Calcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium  Chemical Structure
  66. GC18922 Camalexin Camalexin is an alkaloid released by plants of the Brassicaceae family in response to pathogen infection. Camalexin  Chemical Structure
  67. GC32147 Carbendazim Carbendazim is a potent and orally active broad-spectrum?benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria,?Fusarium?and?Sclerotina. Carbendazim  Chemical Structure
  68. GC32331 Carboxin (Carboxine) Carboxin (Carboxine) (Carboxin (Carboxine)e) is a systemic agricultural fungicide and seed protectant. Carboxin (Carboxine)  Chemical Structure
  69. GC35612 Carvacrol Carvacrol is a monoterpenoid phenol isolated from Thymus mongolicus Ronn. Carvacrol  Chemical Structure
  70. GC10303 Caspofungin Acetate Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin Acetate  Chemical Structure
  71. GC64117 Caulilexin C Caulilexin C is a phytoalexin from crucifers with antifungal activity. Caulilexin C  Chemical Structure
  72. GC60100 Cauloside A Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A  Chemical Structure
  73. GC38681 Cedrol A sesquiterpene alcohol Cedrol  Chemical Structure
  74. GC15391 Cercosporamide A potent inhibitor of fungal Pkc1 and mammalian Mnk isoforms Cercosporamide  Chemical Structure
  75. GC65430 Cerebroside B Cerebroside B, a sphingolipid compound, is a non-racespecific elicitor, which elicits defense responses in rice. Cerebroside B  Chemical Structure
  76. GC32394 Chlordantoin (Clodantoin) Chlordantoin (Clodantoin) is an antifungal agent and has the potential for vaginal candidiasis treatment. Chlordantoin (Clodantoin)  Chemical Structure
  77. GC39601 Chlormidazole hydrochloride Chlormidazole hydrochloride is an antifungal agent and has inhibitory activity against many fungi and some gram-positive cocci. Chlormidazole hydrochloride  Chemical Structure
  78. GC39358 Chlorobutanol Chlorobutanol is a pharmaceutical preservative. Chlorobutanol  Chemical Structure
  79. GC62358 Chlorobutanol hemihydrate Chlorobutanol hemihydrate is a pharmaceutical preservative. Chlorobutanol hemihydrate  Chemical Structure
  80. GC47082 Chlorothalonil A broad-spectrum organochlorine fungicide Chlorothalonil  Chemical Structure
  81. GC60701 Chlorphenesin Chlorphenesin is a reversible antigen-associated immunosuppressant. Chlorphenesin  Chemical Structure
  82. GC17540 Chlorquinaldol Antifungal and antibacterial Chlorquinaldol  Chemical Structure
  83. GC10132 Ciclopirox broad-spectrum antifungal agent Ciclopirox  Chemical Structure
  84. GC11120 Ciclopirox ethanolamine Ciclopirox ethanolamine (Ciclopirox ethanolamine) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox ethanolamine  Chemical Structure
  85. GC16661 Citrinin A mycotoxin inducing apoptosis Citrinin  Chemical Structure
  86. GC65557 Cladosporin Cladosporin is a fungal metabolite produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin  Chemical Structure
  87. GC11460 Climbazole Broad-spectrum imidazole antifungal agent Climbazole  Chemical Structure
  88. GC32078 Clioquinol (Iodochlorhydroxyquin) Clioquinol (Iodochlorhydroxyquin) (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol (Iodochlorhydroxyquin)  Chemical Structure
  89. GC16804 Clotrimazole antifungal compound Clotrimazole  Chemical Structure
  90. GC32184 Cloxiquine (5-Chloro-8-quinolinol) Cloxiquine (5-Chloro-8-quinolinol) (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine (5-Chloro-8-quinolinol)  Chemical Structure
  91. GC63892 Colutehydroquinone Colutehydroquinone is an isoflavonoid that can be found in the root bark of Colutea arborescens. Colutehydroquinone  Chemical Structure
  92. GC35725 Coniferin Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin  Chemical Structure
  93. GC35726 Coniferyl alcohol A monolignol Coniferyl alcohol  Chemical Structure
  94. GC64090 Corydalmine Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi. Corydalmine  Chemical Structure
  95. GC35732 Corypalmine Corypalmine is an alkaloid from Corydalis chaerophylla. Corypalmine  Chemical Structure
  96. GC65545 Cyclo(L-Phe-L-Pro) Cyclo(L-Phe-L-Pro)  Chemical Structure
  97. GC17198 Cycloheximide

    Cycloheximide is an antibiotic that inhibits protein synthesis at the translation level, acting exclusively on cytoplasmic (80s) ribosomes of eukaryotes.

    Cycloheximide  Chemical Structure
  98. GC45904 Cyclosporin C A fungal metabolite with diverse biological activities Cyclosporin C  Chemical Structure
  99. GC60736 Cymoxanil A cyanoacetamide fungicide Cymoxanil  Chemical Structure
  100. GC47159 Cyprodinil An anilinopyrimidine fungicide Cyprodinil  Chemical Structure
  101. GC43358 Cytochalasin A The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. Cytochalasin A  Chemical Structure

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