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Fungal

An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host. Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.

Products for  Fungal

  1. Cat.No. Product Name Information
  2. GC12404 (+)-Ketoconazole Potent inhibitor of cytochrome P450c17
  3. GC34950 (-)-Ketoconazole
  4. GC38725 (S,S)-Valifenalate
  5. GC30216 10-Undecenoic acid (Undecylenic acid)
  6. GC30800 10-Undecenoic acid zinc salt (Zinc undecylenate)
  7. GC32375 2,3-Dimethoxybenzaldehyde (o-Veratraldehyde)
  8. GC32389 2,4,6-Tribromophenyl caproate
  9. GC32943 3-(Methylthio)propionic acid (3-Methylsulfanylpropionic acid)
  10. GC33976 4',7-Dimethoxyisoflavone (Dimethoxydaidzein)
  11. GC33949 4-Chlorosalicylic acid
  12. GN10111 5-hydroxymethyl-2-furaldehyde Extracted from Cornus officinalis Sieb. et Zucc.;Suitability:Water,ethanol,ethyl ether,acetone,carbon tetrachloride;Store the product in sealed,cool and dry condition
  13. GC35232 Acetyllovastatin
  14. GC32379 Aliconazole
  15. GC35306 alpha-Mangostin
  16. GN10484 Amentoflavone Extracted from Cunninghamia lanceolata needles;Store the product in sealed, cool and dry condition
  17. GC18131 Aminothiazole Thyroid inhibitor
  18. GC15052 Amorolfine HCl antifungal reagent
  19. GC14092 Amphotericin B amphipathic polyene antibiotic
  20. GC15026 AN-2690 Antifungal agent
  21. GC32324 AN2718

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