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Fungal

An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host. Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.

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Products for  Fungal

  1. Cat.No. Product Name Information
  2. GC61670 Methyl p-coumarate Methyl p-coumarate (Methyl 4-hydroxycinnamate), an esterified derivative of p-Coumaric acid (pCA), is isolated from the flower of Trixis michuacana var longifolia. Methyl p-coumarate  Chemical Structure
  3. GC32244 Micafungin (FK463) Micafungin (FK463) (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase. Micafungin (FK463)  Chemical Structure
  4. GC17507 Micafungin sodium An echinocandin antifungal Micafungin sodium  Chemical Structure
  5. GC10541 Miconazole imidazole antifungal agent Miconazole  Chemical Structure
  6. GC17493 Miconazole Nitrate Antifungal agent Miconazole Nitrate  Chemical Structure
  7. GC15592 Moniliformin (sodium salt) induces mitotic arrest at the metaphase stage Moniliformin (sodium salt)  Chemical Structure
  8. GC38164 Multifungin Multifungin  Chemical Structure
  9. GC30867 Myclobutanil An Analytical Reference Standard Myclobutanil  Chemical Structure
  10. GC64165 N-Decyl-N,N-dimethyldecan-1-aminium chloride N-Decyl-N,N-dimethyldecan-1-aminium chloride (Didecyldimethylammonium chloride) is a dialkyl-quaternary ammonium compound that is used in numerous products for its bactericidal, virucidal and fungicidal properties. N-Decyl-N,N-dimethyldecan-1-aminium chloride  Chemical Structure
  11. GC11363 Naftifine HCl Naftifine HCl is an antibiotic. Naftifine HCl  Chemical Structure
  12. GC12381 Natamycin

    Antifungal macrolide polyene

    Natamycin  Chemical Structure
  13. GC40669 Nerol Nerol is a monoterpene and isomer of geraniol that has been found in a variety of plants, including Cannabis. Nerol  Chemical Structure
  14. GC41343 Nerolidol Nerolidol is a sesquiterpene found in a variety of plants, including C. Nerolidol  Chemical Structure
  15. GC39408 Neticonazole Neticonazole is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole  Chemical Structure
  16. GC39409 Neticonazole hydrochloride Neticonazole hydrochloride is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole hydrochloride  Chemical Structure
  17. GC13793 NH125 Selective eEF-2 kinase inhibitor NH125  Chemical Structure
  18. GC62709 Nikkomycin Z Nikkomycin Z, a nucleoside-peptide, is a selective competitive chitin synthesis inhibitor. Nikkomycin Z  Chemical Structure
  19. GC46185 Nimbin A limonoid with diverse biological activities Nimbin  Chemical Structure
  20. GC13632 Nourseothricin (sulfate) broad-spectrum antibiotic Nourseothricin (sulfate)  Chemical Structure
  21. GC10090 Nystatin (Fungicidin) Nystatin (Fungicidin) is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin (Fungicidin)  Chemical Structure
  22. GC67746 o-Vanillin o-Vanillin  Chemical Structure
  23. GC44485 Ochratoxin C Ochratoxin C is the ethyl ester analog of ochratoxin A, a mycotoxin produced by A. Ochratoxin C  Chemical Structure
  24. GC16221 Oligomycin C mitochondrial F1FO-ATP synthase inhibitor Oligomycin C  Chemical Structure
  25. GC15233 Ophiobolin B calmodulin antagonist Ophiobolin B  Chemical Structure
  26. GC36822 Oteseconazole Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious effect on human CYP51. Oteseconazole  Chemical Structure
  27. GC17528 Oxiconazole (nitrate) antifungal imidazole Oxiconazole (nitrate)  Chemical Structure
  28. GC47854 Paclobutrazol A plant growth retardant Paclobutrazol  Chemical Structure
  29. GC47871 Papyracillic Acid A fungal metabolite Papyracillic Acid  Chemical Structure
  30. GC61453 Penconazole Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole  Chemical Structure
  31. GC10120 Phenothiazine Dopamine-2 (D2) receptor antagonist Phenothiazine  Chemical Structure
  32. GC62158 Picoxystrobin Picoxystrobin is a primary strobilurin fungicide that is widely applied for plant disease control. Picoxystrobin  Chemical Structure
  33. GC61185 Picropodophyllone Picropodophyllone, an aryltetralin lignan, is isolated from leaves of Podophyllum hexandrum, and has antifungal activities. Picropodophyllone  Chemical Structure
  34. GC32203 Piroctone olamine (Piroctone ethanolamine) Piroctone olamine (Piroctone ethanolamine) is a pyridine derivate. Piroctone olamine (Piroctone ethanolamine)  Chemical Structure
  35. GC13964 Pneumocandin B0 potent antifungal and inhibitor of ?-(1,3)-D-glucan synthesis Pneumocandin B0  Chemical Structure
  36. GC17614 Posaconazole Sterol C14ɑ demethylase inhibitor Posaconazole  Chemical Structure
  37. GC11816 Posaconazole hydrate

    C14ɑ demethylase inhibitor

    Posaconazole hydrate  Chemical Structure
  38. GC61204 Posaconazole-D4 Posaconazole-D4 is a deuterium-labeled form of Posaconazole. Posaconazole-D4  Chemical Structure
  39. GC36950 Posaconazole-D5 Posaconazole-D5 is a deuterium-labeled form of Posaconazole. Posaconazole-D5  Chemical Structure
  40. GC25778 Potassium 1-Naphthaleneacetate Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens. Potassium 1-Naphthaleneacetate  Chemical Structure
  41. GC64737 Potassium sorbate Potassium sorbate (Sorbic acid potassium) is a highly efficient, and nonpoisonous?food preservatives. Potassium sorbate  Chemical Structure
  42. GC38218 Proanthocyanidins A polyphenol with antioxidant activity Proanthocyanidins  Chemical Structure
  43. GC32676 Proanthocyanidins A polyphenol with antioxidant activity Proanthocyanidins  Chemical Structure
  44. GC44686 Prochloraz Prochloraz is an imidazole antifungal that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. Prochloraz  Chemical Structure
  45. GC44690 Prodigiosin Prodigiosin is a natural red bacterial pigment that has antibiotic, antitumor, and immunosuppressant properties. Prodigiosin  Chemical Structure
  46. GC65066 Prodigiosin hydrochloride Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride  Chemical Structure
  47. GC47977 Propiconazole A broad-spectrum triazole fungicide Propiconazole  Chemical Structure
  48. GC32248 Propoxur A carbamate insecticide Propoxur  Chemical Structure
  49. GC69770 Protoneogracillin

    Protoneogracillin is a furostanol glycoside with activity in inhibiting the plant pathogenic fungus P.oryzae (MMDC=94.0 μM) and cytotoxicity against K562 cancer cells (IC50=6.6 μM).

    Protoneogracillin  Chemical Structure
  50. GN10180 Pseudolaric acid A Pseudolaric acid A  Chemical Structure
  51. GN10361 Pseudolaric Acid B Pseudolaric Acid B  Chemical Structure
  52. GN10322 Pseudolaric Acid C Pseudolaric Acid C  Chemical Structure
  53. GC44777 Purpurin Purpurin is a naturally occurring reddish-yellow pigment found in madder root (R. Purpurin  Chemical Structure
  54. GC60314 Pyraclostrobin Pyraclostrobin is a strobilurin fungicide that inhibits mitochondrial complex III of fungal and mammalian cells. Pyraclostrobin  Chemical Structure
  55. GC61818 Pyribencarb Pyribencarb is a benzylcarbamate-type fungicide, which is active against a wide range of plant pathogenic fungi. Pyribencarb  Chemical Structure
  56. GC61755 Pyrimethanil Pyrimethanil is an?anilinopyrimidine?and broad-spectrum?contact fungicide for the control of Botrytis spp. Pyrimethanil  Chemical Structure
  57. GC32391 Pyrogallol A natural oxidant Pyrogallol  Chemical Structure
  58. GC37061 Quilseconazole Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes. Quilseconazole  Chemical Structure
  59. GC61666 Quinizarin Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin  Chemical Structure
  60. GC32116 Ravuconazole (BMS-207147) Ravuconazole (BMS-207147) (BMS-207147;ER-30346) is an orally available triazoleantifungle agent that potently inhibits a wide range of fungi. Ravuconazole (BMS-207147)  Chemical Structure
  61. GC41466 Reveromycin A Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. Reveromycin A  Chemical Structure
  62. GC60321 Rezafungin acetate Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate  Chemical Structure
  63. GC61576 Robinetin Robinetin (3,3',4',5',7-Pentahydroxyflavone), a naturally occurring flavonoid with remarkable ‘two color’ intrinsic fluorescence properties, has antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant activity. Robinetin  Chemical Structure
  64. GC69829 Rolusafine

    Rolusafine is an antifungal agent.

    Rolusafine  Chemical Structure
  65. GC39839 S.pombe lumazine synthase-IN-1 S.pombe lumazine synthase-IN-1 is an inhibitor of?lumazine synthases?with?Ki?values of 243 μM and 9.6 μM for?Schizosaccharomyces pombe?and?Mycobacterium tuberculosis?lumazine synthases, respectively. S.pombe lumazine synthase-IN-1  Chemical Structure
  66. GC34773 Sakuranetin

    A flavonoid with diverse biological activities

    Sakuranetin  Chemical Structure
  67. GC32374 Saperconazole (R66905) Saperconazole (R66905) (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L. Saperconazole (R66905)  Chemical Structure
  68. GC68465 SDH-IN-1 SDH-IN-1  Chemical Structure
  69. GC61465 SDZ285428 SDZ285428 is a CYP51 inhibitor. SDZ285428  Chemical Structure
  70. GC16757 Sertaconazole nitrate Broad-spectrum antifungal Sertaconazole nitrate  Chemical Structure
  71. GC30646 Skatole(3-Methylindole) Skatole(3-Methylindole) is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38. Skatole(3-Methylindole)   Chemical Structure
  72. GC38958 Sorbic acid Sorbic acid is a highly efficient, and nonpoisonous?food preservative. Sorbic acid  Chemical Structure
  73. GC18644 Sordarin (sodium salt) Sordarin is a potent diphthamide-dependent eEF2 inhibitor with antifungal properties. Sordarin (sodium salt)  Chemical Structure
  74. GC32268 Stilbamidine (Ba 2652) Stilbamidine (Ba 2652) is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections. Stilbamidine (Ba 2652)  Chemical Structure
  75. GC32221 Sulbentine (Dibenzthione) Sulbentine (Dibenzthione) (Dibenzthione) is an azole antifungal agent that has fungistatic and fungicidal activities. Sulbentine (Dibenzthione)  Chemical Structure
  76. GC11909 Sulconazole Nitrate Sulconazole Nitrate ((±)-Sulconazole Nitrate), an imidazole derivative, is a broad-spectrum fungicide. Sulconazole Nitrate  Chemical Structure
  77. GC63675 T-2307 T-2307, an arylamidine, has antifungal activities in vitro and in vivo. T-2307  Chemical Structure
  78. GC32160 Tebuconazole A triazole fungicide Tebuconazole  Chemical Structure
  79. GC17066 Terbinafine Allylamine antifungal agent Terbinafine  Chemical Structure
  80. GC14576 Terbinafine HCl Terbinafine HCl (TDT 067 hydrochloride) is an orally active and potent antifungal agent. Terbinafine HCl  Chemical Structure
  81. GC32131 Terconazole (R42470) Terconazole (R42470) is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection. Terconazole (R42470)  Chemical Structure
  82. GC65431 Tetradehydropodophyllotoxin Tetradehydropodophyllotoxin possesses antifungal activity. Tetradehydropodophyllotoxin  Chemical Structure
  83. GC39098 Tetrahydroepiberberine Tetrahydroepiberberine is a isoquinoline alkaloid isolated from Corydalis impatiens (Pall). Tetrahydroepiberberine  Chemical Structure
  84. GC32150 Thifluzamide Thifluzamide, a broad-spectrum succinate dehydrogenase inhibitor (SDHI) fungicide, has been widely used in the controlling of a variety of fungal diseases in rice fields. Thifluzamide  Chemical Structure
  85. GC34839 Thiophanate-Methyl

    Thiophanate-Methyl is a systematic fungicide.

    Thiophanate-Methyl  Chemical Structure
  86. GC38951 Thymol iodide Thymol iodide is a compound of Iodide and Thymol. Thymol iodide  Chemical Structure
  87. GC68144 Ticlatone Ticlatone  Chemical Structure
  88. GC14617 Tioconazole antifungal medication Tioconazole  Chemical Structure
  89. GC10337 Tolnaftate anti-fungal agent Tolnaftate  Chemical Structure
  90. GC61896 trans-Chalcone trans-Chalcone, isolated from Aronia melanocarpa skin, is a biphenolic core structure of flavonoids precursor. trans-Chalcone  Chemical Structure
  91. GC33538 Triacetin (Glyceryl triacetate) Triacetin (Glyceryl triacetate) is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin. Triacetin (Glyceryl triacetate)  Chemical Structure
  92. GC45078 Triadimefon Triadimefon is a triazole fungicide used to control powdery mildew, rusts, and other fungal pests on grains, fruit and vegetable crops, turf, shrubs, and trees. Triadimefon  Chemical Structure
  93. GC45079 Triadimenol Triadimenol is a metabolite of triadimefon, a broad-spectrum chiral triazole fungicide, that is formed by reduction of a carbonyl group to the corresponding alcohol. Triadimenol  Chemical Structure
  94. GC13311 Triclosan broad-spectrum antibacterial agent Triclosan  Chemical Structure
  95. GC34845 Trifloxystrobin

    A fungicide

    Trifloxystrobin  Chemical Structure
  96. GC32041 Triphala Triphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica. Triphala  Chemical Structure
  97. GC45091 Triticonazole Triticonazole is a triazole fungicide used for the control of common soil and seed-borne diseases on cereals and other crops. Triticonazole  Chemical Structure
  98. GC18414 Tyrothricin

    Tyrothricin is a polypeptide antibiotic mixture produced by B.

    Tyrothricin  Chemical Structure
  99. GC38246 Undecanoic acid Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. Undecanoic acid  Chemical Structure
  100. GC70093 Undecanoic acid-d21

    Undecanoic acid-d21 is the deuterated form of Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antifungal properties that can inhibit the production of keratinase and lipase in Trichophyton rubrum cells, as well as the biosynthesis of various phospholipids.

    Undecanoic acid-d21  Chemical Structure
  101. GC45135 Validamycin A Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R. Validamycin A  Chemical Structure

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