HIV
HIV (human immunodeficiency virus) is a lentivirus that infect immune system. It cause immune system failure and lead to AIDS (acquired immnudeficiency syndrome).
Products for HIV
- Cat.No. Product Name Information
- GC36310 Indinavir sulfate Indinavir sulfate (MK-639) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR.
- GC47455 Indinavir-d6 An internal standard for the quantification of indinavir
- GC52395 Indolicidin (trifluoroacetate salt) An antimicrobial peptide
- GC18745 Integracin A Integracin A is an inhibitor of HIV-1 integrase (IC50 = 3.2 μM in an HIV-1 integrase coupled assay).
- GC43905 Integracin B Integracin B is a fungal metabolite and an inhibitor of HIV-1 integrase (IC50 = 6.1 μM in an HIV-1 integrase coupled assay).
- GC36320 InteriotherinA Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior.
- GC32306 Islatravir (MK-8591) Islatravir (MK-8591) (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively.
- GC18042 Isoprinosine Isoprinosine is a potent, broad-spectrum antiviral compound for HIV infection.
- GC36350 IT1t IT1t is a potent CXCR4 antagonist; inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM.
- GC10432 IT1t dihydrochloride CXCR4 antagonist, potent
- GC41236 Kazusamycin A Kazusamycin A is an antibiotic from Streptomyces and a hydroxy analog of Leptomycin B that demonstrates cytotoxic activity against various human and mouse tumor lines.
- GC43995 Kazusamycin B Kazusamycin B is a bacterial metabolite originally isolated from Streptomyces.
- GC60978 L-Chicoric Acid A dicaffeoyl ester with diverse biological activities
- GC30862 L-Cycloserine ((S)-4-Amino-3-isoxazolidone) L-Cycloserine ((S)-4-Amino-3-isoxazolidone) ((S)-4-Amino-3-isoxazolidone) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminitransferase in E.
- GC47572 L-Lysine lactam (hydrochloride) A building block
- GC10317 Lamivudine Nucleoside analog reverse transcriptase inhibitor
- GC18345 Leptomycin A Leptomycin A is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins.
- GC16596 Lersivirine An NNRTI
- GC31715 Letrazuril Letrazuril is an anti-HIV agent.
-
GC16589
Limonin
A limonoid
- GC13716 Lopinavir A potent HIV-1 protease inhibitor
- GC47573 Lopinavir-d8 An internal standard for the quantification of lopinavir
- GC32358 Loviride (R 89439) Loviride (R 89439) (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 μM for reverse transcriptase from HIV-1.
- GC44126 Manzamine A Manzamine A is a β-carboline alkaloid with diverse activities that has been found in marine sponges, including X.
-
GC15090
Maraviroc
Maraviroc, the first CCR5 antagonist, has been approved for the treatment of HIV infection, IC50 on hERG ion channel>10μM.
- GC17632 Maslinic Acid inhibitor of NO, H2O2 , IL-6 and TNF-α
- GC36550 Mavorixafor trihydrochloride Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.
- GC11688 Megestrol Acetate Anti-estrogen agent
- GC10811 Miltefosine PI3K/Akt inhibitor
- GC39814 Mitoguazone Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity.
- GC45998 Mitoxantrone-d8 An internal standard for the quantification of mitoxantrone
- GC32390 MIV-150 (PC 815) MIV-150 (PC 815) is a nonnucleoside reverse transcriptase (NNRT) inhibitor, blocking HIV-1 and HIV-2 infections, with an EC50<1 nM against HIV-1/HIV-2MN.
- GC15561 MK-2048
- GC31881 MS417 (GTPL7512) MS417 (GTPL7512) is a selective BET-specific BRD4 inhibitor, binds to BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32.7 μM).
- GC49388 N-Butyldeoxynojirimycin-d9 (hydrochloride) An internal standard for the quantification of N-butyldeoxynojirimycin
- GC47741 Nalanthalide A fungal metabolite with potassium channel inhibitory and antiviral activities
-
GC63095
Nandrolone decanoate
An Analytical Reference Standard
- GC65905 NBD-14189 NBD-14189 is a potent HIV-1 entry antagonist with an IC50 of 89 nM against the HIV-1HXB2 pseudovirus. NBD-14189 binds to HIV-1 gp120 and shows potent antiviral activity (EC50<200 nM).
- GC65903 NBD-14270 NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100 μM).
- GC16035 NBD-556 A small molecule CD4 mimetic
- GC36702 NBD-557 NBD-557 is a potentially HIV-1 inhibitor.
- GC17709 Nelfinavir HIV-1 protease inhibitor
- GC14084 Nelfinavir Mesylate An HIV-1 protease inhibitor
- GC45926 Nelfinavir-d3 An internal standard for the quantification of nelfinavir
- GC16387 Nevirapine Non-nucleoside reverse transcriptase inhibitor
- GC47770 Nevirapine-d4 An internal standard for the quantification of nevirapine
- GC61879 Nifeviroc Nifeviroc is an orally active CCR5 antagonist.
- GC61134 Nigranoic acid Nigranoic acid is a triterpenoid separated from Schisandra chinensis.
- GC47810 O-11 A myristic acid analog with selective toxicity for trypanosomes
- GC14784 O-Methylviridicatin blocks activation of the HIV long terminal repeat by TNF-α
- GN10184 Oleanolic acid
- GC36798 Oleanonic acid Oleanonic acid (3-Oxooleanolic acid) is a triterpenoid, inhibits infection by HIV-1 in in vitro infected PBMC, naturally infected PBMC and monocyte/macrophages with EC50 of 22.7 mM, 24.6 mM and 57.4 mM, respectively.
- GC12821 Oltipraz Nrf2 activator;An antischistosomal agent
- GC62210 ONX-0914 TFA ONX-0914 (PR-957) TFA is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome.
- GP10160 Oritavancin(LY-333328) Oritavancin(LY-333328) (LY 333328) is an orally active glycopeptide antibiotic with activity against gram-positive organisms.
- GC49073 Oxanosine A guanosine analog with diverse biological activities
- GC31140 Oxindole (Indolin-2-one) Oxindole (Indolin-2-one) (Indolin-2-one) is an aromatic heterocyclic building block.
- GC18964 Palitantin Palitantin is a fungal metabolite originally isolated from P.
- GC12257 Panobinostat (LBH589) A pan-HDAC inhibitor
- GC61168 Peldesine Peldesine (BCX 34) is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively.
- GC61633 Peldesine dihydrochloride Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively.
- GC31685 Pentosan Polysulfate Pentosan Polysulfate is an orally bioavailable medication with anti-inflammatory and pro-chondrogenic properties.
- GC61171 Pentosan Polysulfate Sodium (W/W 43%) Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties.
- GC40685 Pentoxifylline Pentoxifylline is a methylxanthine derivative.
- GC32309 Peptide T Peptide T is an octapeptide from the V2 region of HIV-1 gp120.
- GC32335 Peptide T TFA Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120.
- GC13875 Piperaquine used in combination with artimesinin for inhibition of HIV-1 replication
- GC49441 Plerixafor (hydrochloride hydrate) An antagonist of CXCR4
- GC47963 Plerixafor-d4 An internal standard for the quantification of plerixafor
- GC63302 PMEDAP PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication.
- GC32327 PNU-103017 PNU-103017 is an HIV protease inhibitor.
- GC16825 Probenecid inhibitor of organic anion transport, MRP and pannexin-1 channel
- GC33944 Pseudothymidine (5-Methyl-2'-Deoxypseudouridin) Pseudothymidine (5-Methyl-2'-Deoxypseudouridin) is a C-nucleoside analog of thymidine.
- GN10451 Psoralen
- GC11956 Raltegravir (MK-0518)
- GC15036 Raltegravir potassium salt Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection.
- GC63523 Reverse transcriptase-IN-1 Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor.
- GC18659 Ribavirin 5'-monophosphate (lithium salt) Ribavirin 5'-monophosphate inhibits viral DNA and RNA replication in vitro via the strong competitive inhibition of inosine monophosphate dehydrogenase (IMPDH), with a reported Ki value of 270 nM, and thus inhibits guanosine triphosphate synthesis.
- GC33932 RIG-1 modulator 1 RIG-1 modulator 1 is an anti-viral compound which can be useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV extracted from patent WO 2015172099 A1.
- GC11059 Rilpivirine A non-nucleoside reverse transcriptase inhibitor
- GC17303 Ritonavir An HIV protease inhibitor
- GC64331 Ritonavir-13C,d3
- GC40221 Ritonavir-d6 Ritonavir-d6 is intended for use as an internal standard for the quantification of ritonavir by GC- or LC-MS.
- GC18382 RN-18 RN-18 is an inhibitor of HIV-1 viral infectivity factor (Vif), an HIV-1 regulatory protein that does not have cellular homologs.
- GC63979 Ro24-7429 Ro24-7429 is a potent and orally active HIV-1 transactivator protein Tat antagonist.
- GC16629 Rolipram A phosphodiesterase-4 inhibitor
- GC14199 RVX-208 RVX-208 (RVX-208) is an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain. The IC50s are 87 μM and 0.51 μM for BD1 and BD2, respectively.
- GC17906 S/GSK1349572 A potent inhibitor of HIV integrase
- GC18016 Salicylanilide Antiviral,antibacterial,antifungal reagent
- GC15335 Saquinavir
- GC15785 Saquinavir mesylate An HIV protease inhibitor
- GC39642 SARS-CoV-IN-2 SARS-CoV-IN-2 is an effective inhibitor of SARS-CoV replication.
- GC39563 SARS-CoV-IN-3 SARS-CoV-IN-3 is an effective inhibitor of SARS-CoV replication.
- GN10001 Sennoside A
- GN10216 Shikonin
- GC44889 Siamycin I Siamycin I is a tricyclic peptide originally isolated from Streptomyces and has antiviral and antibacterial activities.
- GC32192 Sodium copper chlorophyllin Sodium copper chlorophyllin exerts antiviral activities against Influenza virus and HIV with IC50s of 50 to 100 μM for both of them.
- GC61284 Soyasaponin II Soyasaponin II is a saponin with antiviral activity.
- GC60344 Sparstolonin B Sparstolonin B acts as a selective TLR2 and TLR4 antagonist and selectively blocks TLR2- and TLR4-mediated inflammatory signaling.
- GC48096 Sporogen-AO 1 A fungal metabolite with diverse biological activities