Reverse Transcriptase
Reverse transcriptase, also known as RNA-directed DNA polymerase catalyzes the transcription of RNA into DNA. It is key to the retroviruses infection.
Products for Reverse Transcriptase
- Cat.No. Product Name Information
- GC33990 2,2'-Anhydrouridine (2,2'-Cyclouridine) 2,2'-Anhydrouridine (2,2'-Cyclouridine) is used for anticancer and antiviral research.
- GC65085 3'-Azido-3'-deoxy-5-methylcytidine 3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells.
- GC10387 3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine.
- GC35130 4'-Ethynyl-2'-deoxyadenosine 4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
- GC13805 Abacavir
- GC11274 Abacavir sulfate Reverse transcriptase inhibitor
- GC46767 Abacavir-d4 An internal standard for the quantification of abacavir
- GC42731 Adefovir Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor.
- GC16841 Adefovir Dipivoxil Reverse transcriptase inhibitor
- GC11744 AG 555 Potent EGFR-kinase inhibitor
- GC32381 BF738735 BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC50 of 5.7 nM.
- GC64261 Censavudine Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor.
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GN10346
Corilagin
A natural polyphenol
- GC35731 Corydine Corydine is a naturally occurring alkaloid which can be extracted from plants such as Croton echinocarpus leaves.
- GN10072 Daidzin
- GC14452 Dapivirine (TMC120) Dapivirine (TMC120) (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI).
- GC35835 Delavirdine Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI).
- GC15452 Delavirdine mesylate Non-nucleoside reverse transcriptase inhibitor
- GC64590 Dexelvucitabine Dexelvucitabine (Reverset; d-d4FC), a Cytidine analog, is an orally active nucleoside reverse transcriptase inhibitor.
- GC15330 Didanosine Reverse transcriptase inhibitor
- GC49022 Didanosine-d2 An internal standard for the quantification of didanosine
- GC19126 Doravirine Doravirine is a novel non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus (95% inhibitory concentration 19 nM, 50% human serum).
- GC12389 Efavirenz Reverse transcriptase inhibitor
- GC62607 EFdA-TP tetraammonium EFdA-TP tetraammonium is a potent nucleoside reverse transcriptase (RT) inhibitor.
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GC13653
Emtricitabine
Reverse transcriptase inhibitor
- GC43600 Emtricitabine S-oxide Emtricitabine S-oxide is a potential impurity found in commercial preparations of emtricitabine.
- GC16092 Entecavir Hydrate Entecavir Hydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.
- GC15996 Etravirine (TMC125) Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
- GC33536 Etravirine D4 (TMC-125 D4) Etravirine D4 (TMC-125 D4) (TMC-125 D4) is the deuterium labeled Etravirine.
- GC45825 Etravirine-d6 An internal standard for the quantification of etravirine
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GC63541
FNC-TP
FNC-TP is the intracellular active form of FNC.
- GN10104 Gramine
- GC12679 GS-7340 GS-7340 (GS-7340) is an investigational oral prodrug of Tenofovir.
- GC32306 Islatravir (MK-8591) Islatravir (MK-8591) (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively.
- GC10317 Lamivudine Nucleoside analog reverse transcriptase inhibitor
- GC16596 Lersivirine An NNRTI
- GC32358 Loviride (R 89439) Loviride (R 89439) (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 μM for reverse transcriptase from HIV-1.
- GC16387 Nevirapine Non-nucleoside reverse transcriptase inhibitor
- GC47770 Nevirapine-d4 An internal standard for the quantification of nevirapine
- GC61134 Nigranoic acid Nigranoic acid is a triterpenoid separated from Schisandra chinensis.
- GC10084 Pyridoxal 5 phosphate Pyridoxal 5 phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.
- GC65207 R-10015 R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1.
- GC11059 Rilpivirine A non-nucleoside reverse transcriptase inhibitor
- GC25867 Rilpivirine Hydrochloride Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
- GC62223 Ro-0335 RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.
- GC37674 SPK-601 SPK-601 (LMV-601) is an inhibitor of the phosphatidylcholine-specific phospholipase C (PC-PLC).
- GC63486 Stampidine Stampidine is a nucleoside reverse transcriptase inhibitor (NRTI) with potent and broad-spectrum anti-HIV activity.
- GC12830 Stavudine (d4T) Stavudine (d4T) (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI).
- GC37690 Stavudine sodium Stavudine (d4T) sodium is an orally active nucleoside reverse transcriptase inhibitor (NRTI).
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GC12125
Tenofovir
HIV reverse transcriptase inhibitor
- GC37758 Tenofovir alafenamide fumarate Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir.
- GC37759 Tenofovir alafenamide hemifumarate Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral prodrug of Tenofovir.
- GC60357 Tenofovir diphosphate Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT).
- GC60358 Tenofovir diphosphate triethylamine Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT).
- GC37760 Tenofovir Disoproxil Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
- GC15067 Tenofovir Disoproxil Fumarate Antiretroviral agent( HIV-1 RT inhibitor)
- GC13846 Tenofovir hydrate Reverse transcriptase inhibitor
- GC15488 Tenofovir maleate Reverse transcriptase inhibitor
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GC70089
Ulonivirine
Ulonivirine (MK-8507) is an orally active non-nucleoside reverse transcriptase inhibitor with high antiviral activity. It can be used for research on HIV-1 infection.
- GC14720 Zalcitabine Reverse transcriptase inhibitor