Reverse Transcriptase
Reverse transcriptase, also known as RNA-directed DNA polymerase catalyzes the transcription of RNA into DNA. It is key to the retroviruses infection.
Products for Reverse Transcriptase
- Cat.No. Product Name Information
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GC90803
2',3'-Dideoxyadenosine-5'-O-triphosphate (sodium salt)
A reverse transcriptase inhibitor and an active metabolite of ddA and ddI
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GC33990
2,2'-Anhydrouridine (2,2'-Cyclouridine)
2,2′-Anhydrouridine, NSC 157148
2,2'-Anhydrouridine (2,2'-Cyclouridine) is used for anticancer and antiviral research. -
GC65085
3'-Azido-3'-deoxy-5-methylcytidine
3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells.
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GC10387
3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt)
AZT glucuronide,Zidovudine glucuronide
Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. -
GC35130
4'-Ethynyl-2'-deoxyadenosine
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
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GC13805
Abacavir
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GC11274
Abacavir sulfate
Reverse transcriptase inhibitor
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GC46767
Abacavir-d4
An internal standard for the quantification of abacavir
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GC42731
Adefovir
GS-0393, PMEA
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor. -
GC16841
Adefovir Dipivoxil
GS 0840
Reverse transcriptase inhibitor -
GC11744
AG 555
Tyrphostin AG-555, Tyrphostin B46
Potent EGFR-kinase inhibitor -
GC42784
AMI-1 (sodium salt)
Arginine N-Methyltransferase Inhibitor-1
Protein arginine methyltransferases (PRMTs) post-translationally modify proteins, including histones, and in this way regulate gene expression, signal transduction, and protein-protein interactions. -
GC32381
BF738735
BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC50 of 5.7 nM.
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GC64261
Censavudine
OBP-601; BMS-986001
Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor. -
GN10346
Corilagin
A natural polyphenol
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GC35731
Corydine
(+)-Corydine
Corydine is a naturally occurring alkaloid which can be extracted from plants such as Croton echinocarpus leaves. -
GN10072
Daidzin
Daidzoside, NPI 031D
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GC14452
Dapivirine (TMC120)
TMC 120;TMC-120
Dapivirine (TMC120) (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). -
GC35835
Delavirdine
Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI).
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GC15452
Delavirdine mesylate
U 90152 mesylate; BHAP-U 90152 mesylate
Non-nucleoside reverse transcriptase inhibitor -
GC64590
Dexelvucitabine
Reverset; d-d4FC
Dexelvucitabine (Reverset; d-d4FC), a Cytidine analog, is an orally active nucleoside reverse transcriptase inhibitor. -
GC15330
Didanosine
ddl, 2′,3′-Dideoxyinosine, NSC 612049
Reverse transcriptase inhibitor -
GC49022
Didanosine-d2
ddl-d2, 2′,3′-Dideoxyinosine-d2
An internal standard for the quantification of didanosine -
GC19126
Doravirine
MK-1439
Doravirine is a novel non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus (95% inhibitory concentration 19 nM, 50% human serum). -
GC12389
Efavirenz
DMP 266, EFV, L-743,726
Reverse transcriptase inhibitor -
GC62607
EFdA-TP tetraammonium
EFdA-TP tetraammonium is a potent nucleoside reverse transcriptase (RT) inhibitor.
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GC70801
EFdA-TP tetralithium
EFdA-TP tetralithium is a potent nucleoside reverse transcriptase (RT) inhibitor.
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GC13653
Emtricitabine
BW 1592, BW 524W91, FTC
Reverse transcriptase inhibitor
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GC43600
Emtricitabine S-oxide
Emtricitabine S-oxide is a potential impurity found in commercial preparations of emtricitabine.
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GC16092
Entecavir Hydrate
BMS 200475, SQ 34,676
Entecavir Hydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell. -
GC15996
Etravirine (TMC125)
R165335, TMC125
Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. -
GC33536
Etravirine D4 (TMC-125 D4)
Etravirine D4 (TMC-125 D4) (TMC-125 D4) is the deuterium labeled Etravirine.
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GC45825
Etravirine-d6
R165335-d6, TMC125-d6
An internal standard for the quantification of etravirine -
GC63541
FNC-TP
FNC-TP is the intracellular active form of FNC.
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GN10104
Gramine
NSC 16892
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GC32306
Islatravir (MK-8591)
4’Ed2FA, 4′-ethynyl-2-fluoro-2′-Deoxyadenosine, EFDA, MK-8591
Islatravir (MK-8591) (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. -
GC10317
Lamivudine
(-)-BCH 189, 3TC, 2’,3’-dideoxy-3’-Thiacytidine
Nucleoside analog reverse transcriptase inhibitor -
GC16596
Lersivirine
UK-453,061
An NNRTI -
GC32358
Loviride (R 89439)
Loviride (R 89439) (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 μM for reverse transcriptase from HIV-1.
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GC16387
Nevirapine
BIRG 587, NSC 641530, NVP
Non-nucleoside reverse transcriptase inhibitor -
GC47770
Nevirapine-d4
NVP-d4
An internal standard for the quantification of nevirapine -
GC61134
Nigranoic acid
Nigranoic acid is a triterpenoid separated from Schisandra chinensis.
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GC10084
Pyridoxal 5 phosphate
Pyridoxal 5 phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.
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GC65207
R-10015
R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1.
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GC11059
Rilpivirine
R278474, TMC278
A non-nucleoside reverse transcriptase inhibitor -
GC25867
Rilpivirine Hydrochloride
TMC278
Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. -
GC62223
Ro-0335
VM 1500A
RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates. -
GC37674
SPK-601
SPK-601 (LMV-601) is an inhibitor of the phosphatidylcholine-specific phospholipase C (PC-PLC).
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GC63486
Stampidine
Stampidine is a nucleoside reverse transcriptase inhibitor (NRTI) with potent and broad-spectrum anti-HIV activity.
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GC12830
Stavudine (d4T)
BMY 27857, d4T, NSC 163661
Stavudine (d4T) (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). -
GC37690
Stavudine sodium
Stavudine (d4T) sodium is an orally active nucleoside reverse transcriptase inhibitor (NRTI).
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GC48103
Stavudine-13C-d3
A neuropeptide with diverse biological activities
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GC12125
Tenofovir
GS1275, GS1278, (R)PMPA, TDF
HIV reverse transcriptase inhibitor
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GC37758
Tenofovir alafenamide fumarate
Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir.
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GC37759
Tenofovir alafenamide hemifumarate
Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral prodrug of Tenofovir.
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GC60357
Tenofovir diphosphate
Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT).
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GC60358
Tenofovir diphosphate triethylamine
TFV-DP triethylamine
Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT). -
GC37760
Tenofovir Disoproxil
Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
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GC15067
Tenofovir Disoproxil Fumarate
Bis(POC)-PMPA
Antiretroviral agent( HIV-1 RT inhibitor) -
GC13846
Tenofovir hydrate
Reverse transcriptase inhibitor
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GC15488
Tenofovir maleate
Reverse transcriptase inhibitor
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GC90702
Triciribine Phosphate
An Akt activation inhibitor and active metabolite of triciribine
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GC70089
Ulonivirine
MK-8507
Ulonivirine (MK-8507) is an orally active non-nucleoside reverse transcriptase inhibitor with high antiviral activity. It can be used for research on HIV-1 infection.
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GC14720
Zalcitabine
ddC, 2’,3’Dideoxycytidine, NSC 606170, Ro 242027/000
Reverse transcriptase inhibitor -
GC20228
α-Amyrin
(+)-β-Amyrin, NSC 527971, Olean-12-en3β-ol
α-Amyrin is a pentacyclic triterpenoid.