Reversin 121 |
| Catalog No.GC44821 |
Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 174630-04-7
Sample solution is provided at 25 µL, 10mM.
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Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a Kd value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma membrane vesicles from multidrug-resistant cells, and reconstituted proteoliposomes as well as in a variety of MDR1-expressing intact tumor cells.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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