RI-STAD 2 |
| Catalog No.GC50502 |
AKAP disruptor; selectively binds PKA-RI with high affinity and blocks its interaction with AKAP; cell permeable
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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AKAP disruptor. Selectively binds PKA-RI with high affinity (KD values are 6.2 and 12.1 nM for the RIα and β subunits, respectively) and blocks its interaction with AKAP. Inhibits type I PKA-mediated phosphorylation in live cells. Cell permeable.
Wang et al (2015) PKA-type I selective constrained peptide disruptors of AKAP complexes. ACS Chem.Biol. 10 1502 PMID:25765284
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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