Px -478
Chemically, the full name of PX 478 is S-2-amino3-[4’-N, N,-bis(chloroethyl)amino]phenyl propionic acid N-oxide. It is a small molecule, i.e., having low atomicity and molecular weight. The 2D view of the molecular structure of the PX 478 compound is schematically depicted in Figure 1.
Cy 5.5 NHS ESTER
Chemically, Cy-5.5áN-hydroxysuccinamide ester is the full name of Cy 5.5 NHS ester. It is also known as cyanine 5.5 monosuccinimidyl ester. The Cy 5.5 NHS ester is a small molecule that implies that it has a low atomicity and also a low molecular weight.
The complete two-dimensional view of the molecular structure of the Cy 5.5 NHS ester compound is presented in the form of a schematic diagram in Figure 1.
Cl-Amidine
Chemically, N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide is the full name of Cl-Amidine. The Cl-Amidine molecule is small, i.e., low atomicity and thus low molecular weight. As its name suggests it is an amidine having a halo atom, i.e., chlorine. The two-dimensional view of the molecular structure of the Cl-Amidine compound is diagrammatically presented in Figure 1.
FK866
The full chemical name of the FK866 compound is (E)-N-[4-(1-benzoylpiperidin-4-yl) butyl]-3-(pyridin3-yl) acrylamide. It is also known as (E)-Daporinad and APO866 in the scientific literature. It is a small molecule with low molecular weight, artificially synthesized in laboratory and possess an entirely novel mechanism for its pharmaceutical action. A complete picture two-dimensional view of the molecular structure of the FK866 compound is presented in Figure 1.
OSMI 4
OSMI 4 is a small, synthetic and novel molecule. It has been discovered in a high-throughput screening (HTS) based on fluorescence luminescence. OSMI 4 is also known as OSMI-4b. The two-dimensional view of the Molecular structure of the OSMI 4 compound is diagrammatically depicted in Figure 1.
Enzalutamide
Enzalutamide that is also known as MDV3100, is a small molecule. The complete two-dimensional view of the molecular structure of the Enzalutamide compound is diagrammatically presented in Figure 1. The trifluoromethyl substituted anilide is the most important structure feature of the overall Enzalutamide molecule as it is crucial to its biological activity.
TRASTUZUMAB
Another name for trastuzumab is Herceptin. Trastuzumab is an antibody, i.e., a protein molecule that essentially means being composed of amino acids and has a major key role in providing the body with immunity, which is artificially produced in the laboratory by the monoclone cell/ monoclones; thus, it is also regarded as an immunoglobulin or it can also be more appropriately termed as monoclonal antibody which is shortened as mAb. Trastuzumab is a humanized antibody, i.e., the protein sequence was originally taken from some non-human biological species, then its sequence is modified such that it becomes extremely similar to the antibodies that are naturally produced in the human body in terms of structure.
Cenicriviroc
Cenicriviroc, shortened as CVC is a novel and small compound of potential clinical significance. Other names of Cenicriviroc compound used in the scientific literature include TAK-652, TBR-652. As it was first discovered from the chemical manipulation of TAK-779 compound; it is quite obvious that it is a chemical derivative of the same compound, specifically it is a sulfoxide derivative of TAK-779 compound. Ease of synthesis was the primary stimulus for the further research on this compound.
CL264
CL264 is a small molecule. Owing to structural similarities, CL264 is a chemical derivative of 8-hydroxyadenine.
Talking about the structure of CL264 molecule, it is considered as a chemical analogue, i.e., compounds having a very similar structure despite some minor changes in the structure, of Adenine which a famous nitrogenous base. The two-dimensional view of the molecular structure of the CL264 compound is given in Figure 1.
BYL 719
BLY 719, also known as NVP-BYL719, Piqray or Alpelisib. Talking about the structure, BLY 719 is the chemical derivative of 2-aminothiazole. It was discovered as the most potent and the most selective ligand to effectively target phosphatidylinositol-3-kinase α (PI3Kα), an important target in the cancer chemotherapy. BLY 719 is a small molecule. The two-dimensional view of the molecular structure of the BLY 719 is pictorially represented in Figure 1.