GDC-6036 |
Catalog No.GC64510 |
GDC-6036 (compuesto 17a) es un potente inhibidor de K-Ras G12C con una IC50 de <0,01 μM. GDC-6036 tiene una CE50 de 2 nM en células HCC1171 de alquilaciÓn de K-Ras G12C.
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Cas No.: 2417987-45-0
Sample solution is provided at 25 µL, 10mM.
GDC-6036 (compound 17a) is a potent K-Ras G12C inhibitor with an IC50 of <0.01 μM. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylation HCC1171 cells[1].
[1]. Sushant Malhotra, et al. Fused ring compounds. WO2020097537A2.
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