Inicio>>Signaling Pathways>> Antibody-drug Conjugate/ADC Related>> ADC Cytotoxin>>Glucocorticoid receptor agonist-3

Glucocorticoid receptor agonist-3

Catalog No.GC71458

Glucocorticoid receptor agonist-3 (preparación 6) es un agonista del receptor glucocorticoide.

Products are for research use only. Not for human use. We do not sell to patients.

Glucocorticoid receptor agonist-3 Chemical Structure

Cas No.: 2842165-73-3

Tamaño Precio Disponibilidad Cantidad
1 mg
234,00 $
Disponible
5 mg
594,00 $
Disponible

Tel:(909) 407-4943 Email: sales@glpbio.com


Reseñas de cliente

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.

Description of Glucocorticoid receptor agonist-3

Glucocorticoid receptor agonist-3 (Preparation 6) is a glucocorticoid receptor agonist.

References:
[1]. Grace CHAO, et al. Human tumor necrosis factor alpha antibody glucocorticoid conjugates. Patent, WO2023220549A1.

Chemical Properties of Glucocorticoid receptor agonist-3

Cas No. 2842165-73-3 SDF
Formula C36H40FNO7 M.Wt 617.7
Solubility DMSO : 200 mg/mL (323.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Storage -20°C, sealed storage, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Glucocorticoid receptor agonist-3

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.6189 mL 8.0945 mL 16.1891 mL
5 mM 323.8 μL 1.6189 mL 3.2378 mL
10 mM 161.9 μL 809.5 μL 1.6189 mL
  • Molarity Calculator

  • Dilution Calculator

  • Molecular Weight Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

Calculate

In vivo Formulation Calculator (Clear solution) of Glucocorticoid receptor agonist-3

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

View current batch:

Reseñas

Review for Glucocorticoid receptor agonist-3

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for Glucocorticoid receptor agonist-3

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.