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L-Glutathione Reduced (Synonyms: GSH)

Catalog No.GC12203

Se utilizaba para eluir GST del agarosa de glutatión.

Products are for research use only. Not for human use. We do not sell to patients.

L-Glutathione Reduced Chemical Structure

Cas No.: 70-18-8

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL Water)
37,00 $
Disponible
5g
30,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Product Documents

Quality Control & SDS

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Background

L-Glutatión reducido (GSH; γ-L-glutamil-L-cisteinil-glicina) es un antioxidante endógeno y es capaz de eliminar los radicales libres derivados del oxígeno.

L-Glutatión reducido es un tiol no proteico que existe ampliamente en las células vivas. L-Glutatión reducido desempeña funciones biológicas importantes en el organismo, incluyendo la síntesis de proteínas y ADN, la actividad enzimática, el metabolismo y la protección celular. L-Glutatión reducido es capaz de eliminar los radicales libres derivados del oxígeno y se ha establecido como un marcador de estrés oxidativo[1].

References:
[1]. Pereira-Rodrigues N, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry. 2007 Jan;70(1):147-54.

Chemical Properties

Cas No. 70-18-8 SDF
Sinónimos GSH
Chemical Name (S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-5-oxopentanoic acid
Canonical SMILES SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O
Formula C10H17N3O6S M.Wt 307.32
Solubility ≥ 14.25mg/mL in Water Storage 4°C, protect from light ,unstable in solution, ready to use.
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 3.2539 mL 16.2697 mL 32.5394 mL
5 mM 0.6508 mL 3.2539 mL 6.5079 mL
10 mM 0.3254 mL 1.627 mL 3.2539 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 20 reference(s) in Google Scholar.)

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