Pyridaben (Synonyms: BAS 300, Damanlin, GWN 1715, NC 129) |
| Catalog No.GC48015 |
Pyridaben es un acaricida METI que inhibe el transporte de electrones mitocondriales en el complejo I (METI; Ki = 0,36 nmol/mg de proteÍna en mitocondrias de cerebro de rata).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 96489-71-3
Sample solution is provided at 25 µL, 10mM.
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Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria).1 It is active against a variety of mites, inducing 100% mortality of C. malaccensis, D. farina, and T. putrescentia when administered via filter paper contact at doses of 25, 100, and 200 mg/m3, respectively.2 Pyridaben is toxic to rats when administered orally (LD50s = 570 and 1,100 for female and male rats, respectively) and via inhalation (LD50s = 0.62 and 0.66 mg/L for female and male rats, respectively).3 Formulations containing pyridaben have been used in the control of mites in agriculture.
1.Navarro, A., BÁndez, M.J., GÓmez, C., et al.Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activityJ. Bioenerg. Biomembr.42(5)405-412(2010) 2.Takahashi, M., Shono, T., and Umehara, T.Efficacy of pyridaben against three kinds of mites, Cheyletus malaccensis, Dermatophagoides farinae and Tyrophagus putrescentiaeJpn. J. Sanit. Zool.41(3)257-260(1990) 3.Igarashi, H., and Sakamoto, S.Summary of toxicity studies with pyridabenJ. Pest. Scien.19(4)S243-S251(1994)
| Cas No. | 96489-71-3 | SDF | |
| Sinónimos | BAS 300, Damanlin, GWN 1715, NC 129 | ||
| Canonical SMILES | CC(C)(C)C1=CC=C(CSC2=C(Cl)C(N(C(C)(C)C)N=C2)=O)C=C1 | ||
| Formula | C19H25ClN2OS | M.Wt | 364.9 |
| Solubility | Chloroform: Slightly Soluble | Storage | 4°C, protect from light |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.7405 mL | 13.7024 mL | 27.4048 mL |
| 5 mM | 0.5481 mL | 2.7405 mL | 5.481 mL |
| 10 mM | 0.274 mL | 1.3702 mL | 2.7405 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.50%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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