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(R)-Exatecan Intermediate 1

Catalog No.GC74127

(R)-Exatecan Intermediate 1 es un isómero del Exatecan intermediario 1.

Products are for research use only. Not for human use. We do not sell to patients.

(R)-Exatecan Intermediate 1 Chemical Structure

Cas No.: 110351-91-2

Tamaño Precio Disponibilidad Cantidad
25 mg
47,00 $
Disponible
50 mg
74,00 $
Disponible
100 mg
117,00 $
Disponible
250 mg
211,00 $
Disponible
1 g
421,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description of (R)-Exatecan Intermediate 1

(R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 . Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan , a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer.

Chemical Properties of (R)-Exatecan Intermediate 1

Cas No. 110351-91-2 SDF
Formula C13H13NO5 M.Wt 263.25
Solubility DMSO : 100 mg/mL (379.87 mM; Need ultrasonic) Storage 4°C, stored under nitrogen, away from moisture
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (R)-Exatecan Intermediate 1

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.7987 mL 18.9934 mL 37.9867 mL
5 mM 0.7597 mL 3.7987 mL 7.5973 mL
10 mM 0.3799 mL 1.8993 mL 3.7987 mL
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In vivo Formulation Calculator (Clear solution) of (R)-Exatecan Intermediate 1

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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