Cancer Biology
- Cancer Biology Peptides(42)
- Ras-like GTPases(11)
- Leukemia(1)
- Cell Proliferation, Viability & Cytotoxicity(0)
- Others(7)
- Tumor Microenvironment(44)
- Cell Migration & Metastasis(52)
- Cell Death(6)
Products for Cancer Biology
- Cat.No. Nombre del producto Información
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GC47054
CAY10748
A STING agonist
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GC47064
CAY10770
An inhibitor of CYP4Z1
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GC47066
CAY10777
An antiproliferative agent
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GC91432
CAY10799
Di-tert-butyl (((S)-1-(tert-butoxy)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)carbamoyl)-L-glutamate
CAY10799 es un precursor en la síntesis de ligandos y sondas fluorescentes del antígeno de membrana específico de próstata (PSMA) que se han utilizado en la detección de PSMA en células LNCaP y PC3.
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GC43207
Caylin-1
Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity.
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GC43208
Caylin-2
Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity.
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GC49664
CB-1158
INCB 01158, Numidargistat
An arginase inhibitor -
GP10098
Cdk2/Cyclin Inhibitory Peptide I
H2N-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Pro-Val-Lys-Arg-Arg-Leu-Phe-Gly-OH
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GC16722
CE3F4
CE3F4 es un antagonista selectivo de la proteÍna de intercambio activada directamente por cAMP (Epac1), con IC50 de 10,7 μM y 66 μM para Epac1 y Epac2(B), respectivamente.
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GC65347
Ceanothic acid
El Ácido ceanÓtico (Ácido emÓlico) es un homÓlogo del anillo A del Ácido betulÍnico. El Ácido ceanÓtico inhibe las células OVCAR-3, HeLa y FS-5 con una supervivencia celular del 68 %, 65 % y 81 %, respectivamente.
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GC45716
Cerevisterol
Cerevisterol es un esteroide aislado de los cuerpos fructÍferos de Agaricus blazei.
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GC43244
Chlorin e6
Ce6
Chlorin e6 (Ce6) es un fotosensibilizador de segunda generación. -
GC91297
Cholesterol-Doxorubicin
Una forma de prodroga de doxorrubicina.
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GC43258
Cholesteryl Hemisuccinate
Cholesteryl hydrogen succinate
Cholesteryl Hemisuccinate is an acidic cholesterol ester with hepatoprotective and anticancer activities. -
GC18290
Chrysomycin A
Albacarcin V, NSC 613946, Virenomycin V
Chrysomycin A is an antibiotic isolated from a strain of Streptomyces. -
GC12948
CID-1067700
ML-282
CID-1067700 (ML282) es un inhibidor de pan GTPasa e inhibe competitivamente el Ras relacionado en el cerebro 7 (Rab7) con una Ki de 13 nM. -
GC41578
cis-10-Heptadecenoic Acid
(Z)-Heptadec-10-enoic acid
cis-10-Heptadecenoic acid is a C17:1 monounsaturated fatty acid that is a minor constituent of ruminant fats.
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GC41587
cis-Vaccenic Acid
C18:1 n-7, C18:1(11Z), cis-11-Octadecenoic Acid
El Ácido cis-vaccénico, el extracto antiviral del capsulato de Rhodopseudomonas y el componente activo predominante del capsulato de Rhodopseudomonas, actÚa como un potencial inductor de la hemoglobina fetal. -
GC52367
Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide
Biotin-GQGKS(Cit)L(Cit)DLYEEEMRELRRQ, Biotin-GQGKSXLXDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (G146R) (R144 + R146)-biotin
A biotinylated and citrullinated mutant vimentin peptide -
GC52370
Citrullinated Vimentin (R144) (139-159)-biotin Peptide
Biotin-GQGKS(Cit)LGDLYEEEMRELRRQ, Biotin-GQGKSXLGDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (R144)-biotin
A biotinylated and citrullinated vimentin peptide -
GC47109
Clotrimazole-d5
An internal standard for the quantification of clotrimazole
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GC47117
Colchicine-d6
La colchicina-d6 es la colchicina marcada con deuterio. La colchicina es un inhibidor de la tubulina y un agente disruptor de los microtÚbulos. La colchicina inhibe la polimerizaciÓn de microtÚbulos con una IC50 de 3 nM. La colchicina también es un antagonista competitivo de los receptores de glicina α3 (GlyR).
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GC43299
Collismycin A
SF 2738A
Collismycin A is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibacterial, antiproliferative, and neuroprotective properties. -
GC52018
COTC
2-Crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone
A bacterial metabolite with anticancer activity -
GC49569
CP 226,269
A dopamine D4 receptor agonist
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GC49059
CP94
CGP 46700, 1,2-Diethyl-3-hydroxypyridin-4-one, EL1Net, 1,2-diethyl HP
An iron chelator -
GC62215
CRT0273750
CRT0273750 es un inhibidor de la autotaxina (ATX) y modula los niveles de LPA en plasma (IC50 = 0,014 μM). CRT0273750 se puede utilizar en modelos de cÁncer dependientes de ATX/LPA.
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GC49557
Cu-GTSM
CuII(gtsm), copper-GTSM
A copper-containing compound with diverse biological activities -
GC47137
Cy5-SE (triethylamine salt)
Sulfo-Cy5
La sal de trietilamina Cy5-SE (Cy5 NHS Ester) es un colorante reactivo para el etiquetado de grupos amino en péptidos, proteínas y oligonucleótidos. -
GP10048
Cyclin D1
H2N-Leu-Leu-Gly-Ala-Thr-Cys-Met-Phe-Val-OH
G1/S-specific cyclin-D1 (H2N-Leu-Leu-Gly-Ala-Thr-Cys-Met-Phe-Val-OH) is a protein that in humans is encoded by the CCND1 gene. -
GP10038
Cyclin dependent kinase inhibitor 2A - Tumor Suppressor
H2N-Met-Val-Arg-Arg-Phe-Leu-Val-Thr-Leu-Arg-Ile-Arg-Arg-Ala-Cys-Gly-Pro-Pro-Arg-Val-OH
Cyclin dependent kinase inhibitor 2A (CDKN2A, p16Ink4A) (H2N-Met-Val-Arg-Arg-Phe-Leu-Val-Thr-Leu-Arg-Ile-Arg-Arg-Ala-Cys-Gly-Pro-Pro-Arg-Val-OH), also known as multiple tumor suppressor 1 (MTS-1), is a tumor suppressor protein, which in humans is encoded by the CDKN2A gene.
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GC43342
Cyclo(L-Leu-L-Pro)
Maculosin 6
Cyclo(L-Leu-L-Pro) is a diketopiperazine metabolite that has been isolated from various bacterial and fungal species including Streptomyces. -
GC49707
Cyclo(RGDfC) (trifluoroacetate salt)
c(RGDfC), cyclo(Arg-Gly-Asp-D-Phe-Cys)
A cyclic pentapeptide -
GC49709
cyclo(RGDyC) (trifluoroacetate salt)
c(RGDyC), cyclo(Arg-Gly-Asp-D-Tyr-Cys)
A cyclic pentapeptide -
GP10143
Cytochrome c - pigeon (88-104)
H2N-Lys-Ala-Glu-Arg-Ala-Asp-Leu-Ile-Ala-Tyr-Leu-Lys-Gln-Ala-Thr-Ala-Lys-OH
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GP10007
Cytochrome c fragment (93-108)
H2N-Ala-Asn-Glu-Arg-Ala-Asp-Leu-Ile-Ala-Tyr-Leu-Lys-Gln-Ala-Thr-Lys-OH
Initiates apoptosis
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GP10141
Cytochrome P450 CYP1B1 (190-198) [Homo sapiens]
H2N-Phe-Leu-Asp-Pro-Arg-Pro-Leu-Thr-Val-OH
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GC43361
Cytostatin (sodium salt)
Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice.
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GC91419
CYY292
CYY292 es un inhibidor de PDGFRα, PDGFRβ, FGFR1, -2 y -3 (IC50s = 5.35, 4.6, 28, 28 y 78 nM respectivamente).
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GC43368
D,L-1′-Acetoxychavicol Acetate
ACA, 1'-Acetoxychavicol Acetate, Galangal Acetate
D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants. -
GC43504
D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (sodium salt)
IP6, Phytic Acid
El Ácido fÍtico (hexafosfato de inositol) hexasÓdico es un compuesto de almacenamiento de fÓsforo de semillas y granos de cereales. -
GC47168
Daidzein-d4
An internal standard for the quantification of daidzein
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GC60121
Dasatinib D8
Sprycel-d8
Dasatinib D8 es un Dasatinib marcado con deuterio. Dasatinib es un inhibidor dual de la tirosina quinasa de la familia Bcr-Abl y Src. -
GC48581
Daunorubicinone
(+)-Daunomycinone, NSC 109531
An aglycone form of daunorubicin -
GC40697
DDA
Decadienealdehyde, trans2,4Decadien1al
DDA es un producto de peroxidaciÓn lipÍdica del Ácido linoleico. -
GC43390
Deacetylravidomycin
Deacetylravidomycin is a microbial metabolite that has been found in Streptomyces and has light-dependent antibiotic and anticancer activities.
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GC43391
Decanoic Acid (sodium salt)
C10:0, Capric Acid, Decylic Acid
Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons. -
GC45815
Decanoic Acid-d19
Capric Acid-d19, Decylic Acid-d19
An internal standard for the quantification of decanoic acid -
GC46127
Decanoic Acid-d2
C10:0-d2, Capric Acid-d2, Decylic Acid-d2
An internal standard for the quantification of decanoic acid -
GC45722
Decanoic Acid-d3
Capric Acid-d3, Decylic Acid-d3
An internal standard for the quantification of decanoic acid -
GC40230
Deferasirox-d4
Deferasirox-d4 es el deuterio etiquetado como Deferasirox. El deferasirox (ICL 670) es un quelante de hierro disponible por vÍa oral que se utiliza para el tratamiento de la sobrecarga transfusional de hierro.
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GC52316
Deferitrin
GT-56-252, (S)-4'-Hydroxydesazadesferrithiocin
An iron chelator and derivative of desferrithiocin -
GC43407
Demethylwedelolactone
Demethylwedelolactone (DWL) is a coumestan, originally isolated from E.
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GC40654
Deoxyviolacein
Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein that has anticancer, antibacterial, and antifungal properties.
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GC47211
Dichlorvos
DDVP, Dichlorovinyl Dimethyl Phosphate, NSC 6738
An organophosphate insecticide -
GC49293
Dichlorvos-d6
DDVP-d6, Dichlorovinyl Dimethyl Phosphate-d6
An internal standard for the quantification of dichlorvos -
GC47215
Dienogest-d8
An internal standard for the quantification of dienogest
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GC52194
Dimethylamino Parthenolide
DMAPT, LC-1
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GC74493
Dinutuximab
Unituxin; APN-311
Dinutuximab (Unituxin; APN-311) es un anticuerpo monoclonal anti-GD2 quimérico, human-murina. -
GC49383
DL-Phenyl-d5-alanine
(±)-Phenyl-d5-alanine
An internal standard for the quantification of DL-phenylalanine -
GC18254
DM1-SMe
DM1-SMe es una forma no conjugada del maytansinoide en IMGN901. DM1-SMe es aproximadamente 3 a 10 veces mÁs potente que el fÁrmaco original Maytansine, con IC50 que van desde 0,003 a 0,01 nM para DM1-SMe en un panel de lÍneas de células tumorales humanas.
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GC48968
Docetaxel (hydrate)
DTX, NSC 628503, RP 56976, Taxotel
An analog of taxol with antitumor properties
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GC47250
Docetaxel-d9
DTX-d9, Taxotel-d9
Docetaxel-d9 (RP-56976-d9) es el docetaxel etiquetado con deuterio. Docetaxel (RP-56976) es un inhibidor de la despolimerizaciÓn de microtÚbulos, con una IC50 de 0,2 μM. Docetaxel atenÚa los efectos de la expresiÓn de los genes bcl-2 y bcl-xL. Docetaxel detiene el ciclo celular en G2/M y conduce a la apoptosis celular. El docetaxel tiene actividad anticancerÍgena. -
GC74603
Domvanalimab
AB154
Domvanalimab (AB154) es un anticuerpo monoclonal humanizado anti-TIGIT. -
GC43565
Doxorubicinol (hydrochloride)
13-Dihydroadriamycin hydrochloride
Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. -
GC40082
Drimentine B
Drimentine B is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria.
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GC43573
Drimentine C
Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria.
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GC49001
DSPE-PEG(2000)-amine (sodium salt)
A PEGylated derivative of DSPE
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GC91884
DSPE-PEG(2000)-Mannose
1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000-Mannose; 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-Polyethylene Glycol-2000-Mannose; 1,2-DSPE-PEG(2000)-Mannose
DSPE-PEG(2000)-Mannose se ha utilizado en la generación de liposomas y micelas mixtas para la administración de agentes anticancerosos a los macrófagos asociados a tumores TAMs in vitro e in vivo. -
GC52333
DSPE-PEG(2000)-NHS
DSPE-PEG(2000)-NHS is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE .
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GC26427
DSPE-PEG2000-Mal ammonium
Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]-, ammonium salt (1:1)
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GC49058
DTPA
Diethylenetriaminepentaacetic Acid, NSC 7340, Pentetic Acid
El DTPA es un compuesto que se utiliza para construir un adsorbente magnético que puede eliminar simultÁneamente metales pesados y colorantes de aguas residuales complejas. -
GC18992
Duclauxin
NSC 258308
Duclauxin decreases proliferation of tumor cells in vitro and increases the lifespan of mice innoculated with Ehrlich ascitic tumor cells. -
GP10022
Dynamin inhibitory peptide
Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro
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GC65123
Eclalbasaponin I
Eclalbasaponin I se aÍsla de Eclipta prostrata L con actividad antitumoral. La eclalbasaponina I inhibe la proliferaciÓn de células de hepatoma smmc-7721 con un valor IC50 de 111,1703 μg/ml.
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GP10030
EGF receptor substrate eps15 acetyl - [Mus musculus]/[Homo sapiens]
Ac-Gln-Glu-Gln-Glu-Asp-Leu-Glu-Leu-Ala-Ile-Ala-Leu-Ser-Lys-Ser-Glu-Ile-Ser-Glu-Ala-OH
EGF receptor substrate eps15 (Eps15) has been identified as a 142-kDa substrate of the EGF receptor1. -
GP10108
EGF-R (661-681) T669 Peptide
H2N-Lys-Arg-Glu-Leu-Val-Glu-Pro-Leu-Thr-Pro-Ser-Gly-Glu-Ala-Pro-Asn-Gln-Ala-Leu-Leu-Arg-OH
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GC43591
Eicosapentaenoyl 1-propanol-2-amide
Monoacylglycerols (MAGs) of ω-3 polyunsaturated fatty acids have diverse physiological and health effects.
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GC49522
EM-12
EM-12
EM-12 (EM-12), un anÁlogo de talidomida teratogénico, es mÁs activo que la talidomida y es mucho mÁs estable para la hidrÓlisis. EM-12 mejora la inducciÓn de 1,2-dimetilhidrazina de adenocarcinomas de colon de rata. -
GC46137
Emestrin
A mycotoxin
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GC49124
EN219
EN219 es un ligando covalente sintético moderadamente selectivo frente a una cisteÍna N-terminal (C8) de RNF114 con una IC50 de 470 nM. EN219 inhibe la autoubiquitinaciÓn mediada por RNF114 y la ubiquitinaciÓn de p21.
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GP10117
Endostatin (84-114)-NH2 (JKC367)
H2N-Pro-Gly-Ala-Arg-Ile-Phe-Ser-Phe-Asp-Gly-Lys-Asp-Val-Leu-Arg-His-Pro-Thr-Trp-Pro-Gln-Lys-Ser-Val-Trp-His-Gly-Ser-Asp-Pro-Asn-NH2
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GC43606
Endothelin-1 (human, porcine) (trifluoroacetate salt)
ET-1
Endothelin-1 is a peptide vasoconstrictor and agonist of endothelin (ET) receptors ETA and ETB (IC50s = 0.15 and 0.12 nM, respectively). -
GC49648
Enobosarm-d4
(S)-Enobosarm-d4
An internal standard for the quantification of enobosarm -
GC48664
Enoxacin-d8 (hydrochloride)
-
GC47297
EP4 Receptor Antagonist 1
El antagonista del receptor EP4 1 es un antagonista competitivo del receptor prostanoide EP4 muy potente y selectivo para la inmunoterapia contra el cÁncer.
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GP10005
Epidermal growth factor receptor (994-1002) acetyl/amide
Ac-Asp-Ser-Asn-Phe-Tyr-Arg-Ala-Leu-Met-amide
EGF-family receptor
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GP10095
Epidermal Growth Factor Receptor Peptide (985-996)
H2N-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH
-
GC72845
Epoetin beta
rhEPO; EPOCH; Genetical recombination
Epoetin β (rhEPO) es una forma recombinante de eritropoyetina. -
GP10132
erbB-2
H2N-Lys-Ile-Phe-Gly-Ser-Leu-Ala-Phe-Leu-OH
-
GC90653
ERX-41
Un inductor de estrés del ER (retículo endoplásmico).
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GC52303
Ethyl Mycophenolate
A potential impurity found in commercial preparations of mycophenolate mofetil
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GC74618
Etigilimab
OMP-313M32
Etigilimab (OMP-313M32), un anticuerpo monoclonal IgG1 humanizado, bloquea la interacción del TIGIT con PVR (CD155; Poliovirus) e inhila la señalización posterior con la destrucción de la célula diana. -
GC15555
Farnesyl Thiosalicylic Acid Amide
FTS Amide,Salirasib Amide
inhibits tumor growth
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GP10123
Fas C- Terminal Tripeptide
Ac-Ser-Leu-Val-OH
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GC60833
FB23
FB23 es un inhibidor potente y selectivo de la FTO desmetilasa con una IC50 de 60 nM. FB23 se une directamente a FTO e inhibe selectivamente la actividad desmetilasa del ARNm N6-metiladenosina (m6A) de FTO.
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GC46146
FD-211
(-)-Waol A
A δ lactone with anticancer activity -
GC49563
Fenhexamid
KBR 2738
Fenhexamid, un botryticida, es un inhibidor de la biosÍntesis de esteroles. -
GP10146
ferritin heavy chain fragment [Multiple species]
H2N-Tyr-Leu-Asn-Glu-Gln-Val-Lys-Ala-Ile-OH
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GC39811
FIT-039
FIT-039 es un inhibidor de CDK9 selectivo, competitivo con ATP y activo por vÍa oral con una IC50 de 5,8 μM para CKD9/ciclina T1.