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Inicio >> Signaling Pathways >> Cancer Biology

Cancer Biology

Products for  Cancer Biology

  1. Cat.No. Nombre del producto Información
  2. GC49241 Methyl Diethyldithiocarbamate

    DDTC-Me, Diethyldithiocarbamic Acid methyl ester, NSC 133269

     An active metabolite of disulfiram Methyl Diethyldithiocarbamate Chemical Structure
  3. GC47674 Mifepristone-d3

    RU486-d3; RU 38486-d3

     A neuropeptide with diverse biological activities Mifepristone-d3 Chemical Structure
  4. GC74577 Minretumomab

    CC-49

     Minretumomab (CC-49) es un anticuerpo monoclonal murino contra la TAG-72 (glicoproteína 72 asociada al tumor). Minretumomab Chemical Structure
  5. GC50686 Miro1 Reducer Miro1 Reducer Chemical Structure
  6. GC16331 Misonidazole

    NSC 261037,Ro 7-0582,SR 1354

     El misonidazol (Ro 7-0582; SR 1354) es un radiosensibilizador de células tumorales hipÓxicas. Misonidazole Chemical Structure
  7. GC12876 ML-097

    CID-2160985

     ML-097 (CID-2160985) es un activador de GTPasas relacionadas con pan Ras que puede activar Rac1, el ciclo de divisiÓn celular 42, Ras y Rab7. ML-097 Chemical Structure
  8. GC13315 ML-098

    CID-7345532

     ML-098 (CID-7345532) es un activador de la proteÍna de uniÓn a GTP Rab7 con una CE50 de 77,6 nM. ML-098 Chemical Structure
  9. GC16765 ML-099

    CID-888706

     ML-099 (CID-888706) es un activador de GTPasas relacionadas con pan Ras que puede activar Rac1, el ciclo de divisiÓn celular 42, Ras, Rab7 y Rab-2A. ML-099 Chemical Structure
  10. GC18616 MMP-8 Inhibitor I

    Matrix Metalloproteinase-8 Inhibitor I

     MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. MMP-8 Inhibitor I Chemical Structure
  11. GC74487 Modotuximab

    DS 1024; Sym 004

     Modotuximab (Anti-Human EGFR Recombinant anticuerpo) es un anti-cuerpo quimérico de tipo IgG1κ dirigido a la proteína EGFR humana. Modotuximab Chemical Structure
  12. GC61843 Mofezolac

    N-22

     El mofezolac, un fÁrmaco antiinflamatorio no esteroideo (AINE), es un inhibidor de la COX-1 selectivo, reversible y activo por vÍa oral con una IC50 de 1,44 nM. Mofezolac Chemical Structure
  13. GC46176 Multiflorenol A triterpene Multiflorenol Chemical Structure
  14. GC41325 Mycophenolic Acid β-D-Glucuronide

    MPAG，Mycophenolic Acid Glucosiduronate

     Ácido micofenÓlico β-D-Glucuronide es un metabolito del inmunosupresor Ácido micofenÓlico (MPA). El Ácido micofenÓlico β-D-glucurÓnido muestra actividad antitumoral y se puede utilizar en la investigaciÓn del adenocarcinoma. Mycophenolic Acid β-D-Glucuronide Chemical Structure
  15. GP10114 Myelopeptide-2 (MP-2)

    H2N-Leu-Val-Val-Tyr-Pro-Trp-OH

    Myelopeptide-2 (MP-2) Chemical Structure
  16. GC49256 N-acetyl Lenalidomide A metabolite of lenalidomide N-acetyl Lenalidomide Chemical Structure
  17. GC18506 N-Arachidonoyl Dopamine

    NADA

     La N-araquidonoil dopamina es un agonista del receptor CB1 endÓgeno potente y selectivo con una Ki de 250 nM. N-Arachidonoyl Dopamine Chemical Structure
  18. GC47748 N-Arachidonoyl Dopamine-d8

    NADAd8

     An internal standard for the quantification of Narachidonoyl dopamine N-Arachidonoyl Dopamine-d8 Chemical Structure
  19. GC48335 N-glycolyl-Ganglioside GM3 Mixture (ammonium salt)

    GM3-Neugc, NeuGc-GM3, NGcGM3, N-glycolyl-GM3, N-glycolyl-Monosialoganglioside GM3, N-Glycolylneuraminyllactosylceramide

     A mixture of N-glycolyl-ganglioside GM3 N-glycolyl-Ganglioside GM3 Mixture (ammonium salt) Chemical Structure
  20. GC49350 N-Nitroso Sarcosine

    MCMN, N-Methyl-N-(carboxymethyl)nitrosamine

     A carcinogen N-Nitroso Sarcosine Chemical Structure
  21. GC49354 N-Nitroso Sarcosine-d3

    MCMN-d3, N-Methyl-N-(carboxymethyl)nitrosamine-d3

     An internal standard for the quantification of nitroso sarcosine N-Nitroso Sarcosine-d3 Chemical Structure
  22. GC47786 N-Nitroso-N-methyl-4-Aminobutyric Acid

    NMBA

     A tobacco-specific nitrosamine carcinogen N-Nitroso-N-methyl-4-Aminobutyric Acid Chemical Structure
  23. GC49859 N-Nitroso-N-methylaniline

    N-methyl-N-Nitrosoaniline, NMA, NSC 137

     An N-nitrosamine N-Nitroso-N-methylaniline Chemical Structure
  24. GC49731 N-Nitrosodimethylamine-d6

    DMN-d6, DMNA-d6, NDMA-d6, N-Methyl-N-nitrosomethanamine-d6, N,N-Dimethylnitrosamine-d6

     An internal standard for the quantification of N-nitrosodimethylamine N-Nitrosodimethylamine-d6 Chemical Structure
  25. GC49814 N-Nitrosomethylisopropylamine

    NMIPA

     An N-nitrosamine N-Nitrosomethylisopropylamine Chemical Structure
  26. GC52162 N1-Acetylputrescine

    Monoacetylputrescine, N-acetyl Putrescine

     N1-Acetylputrescine Chemical Structure
  27. GC44285 N1-Acetylspermine (hydrochloride)

    N1-Acetylspermine is a monoacetylated derivative of spermine, an endogenous polyamine synthesized from spermidine, that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine.

     N1-Acetylspermine (hydrochloride) Chemical Structure
  28. GC48584 Naftopidil-d5

    KT-611-d5; BM-15275-d5

     Naftopidil-d5 Chemical Structure
  29. GC40081 Nargenicin

    Antibiotic 47444

    Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S.

     Nargenicin Chemical Structure
  30. GC45926 Nelfinavir-d3 An internal standard for the quantification of nelfinavir Nelfinavir-d3 Chemical Structure
  31. GC18750 NEO2734

    EP31670

     NEO2734 (EP31670) es un inhibidor selectivo de bromodominio dual p300/CBP y BET activo por vÍa oral, con valores IC50 de <30 nM para los bromodominios p300/CBP y BET. NEO2734 es activo en el cÁncer de prÓstata mutante SPOP y de tipo salvaje. NEO2734 Chemical Structure
  32. GC47768 Neuromedin U-25 (human) (trifluoroacetate salt)

    NMU-25

     A neuropeptide with diverse roles Neuromedin U-25 (human) (trifluoroacetate salt) Chemical Structure
  33. GC46184 Nexinhib20 An inhibitor of Rab27a-JFC1 protein-protein interactions Nexinhib20 Chemical Structure
  34. GC19843 Nimbolide

    NSC 309909

     Nimbolide es un triterpeno derivado de las hojas y flores de neem (Azadirachta indica L). Nimbolide induce la apoptosis a través de la inactivaciÓn de NF-κB. Nimbolide inhibe la actividad de la quinasa CDK4/CDK6. Nimbolide suprime las vÍas de seÑalizaciÓn NF-κB, Wnt, PI3K-Akt, MAPK y JAK-STAT. Nimbolide Chemical Structure
  35. GC44439 NO-Indomethacin

    NCX 2121

     NO-indomethacin is a hybrid molecule of indomethacin and a nitric oxide (NO) donor. NO-Indomethacin Chemical Structure
  36. GC49316 O-Desmethyl-N-deschlorobenzoyl Indomethacin A metabolite of indomethacin O-Desmethyl-N-deschlorobenzoyl Indomethacin Chemical Structure
  37. GC92048 O12-D3-I3 O12-D3-I3 es un lípido catiónico ionizable (pKa = 6.39) que se ha utilizado en la generación de nanopartículas lipídicas (LNPs) para la administración de siRNA in vitro e in vivo. O12-D3-I3 Chemical Structure
  38. GC47814 Ochratoxin A-13C20

    OTA-13C20

     An internal standard for the quantification of ochratoxin A Ochratoxin A-13C20 Chemical Structure
  39. GC44507 Oligomycin E

    26-hydroxy-28-oxo-Oligomycin A

     Oligomycin E is a minor metabolite of the oligomycin complex produced by several species of Streptomyces. Oligomycin E Chemical Structure
  40. GC49236 Orlistat-d3

    (-)-Tetrahydrolipstatin-d3

     An internal standard for the quantification of orlistat Orlistat-d3 Chemical Structure
  41. GC74609 Osemitamab

    TST001

     Osemitamab es un anticuerpo IgG1 dirigido a humanos claudin-18.2. Osemitamab Chemical Structure
  42. GC74468 Otlertuzumab

    TRU-016

     Otlertuzumab (TRU-016) es un anticuerpo monoclonal humanianti-cd37 que puede usarse para la investigación del cáncer. Otlertuzumab Chemical Structure
  43. GC49073 Oxanosine

    NSC 359452

     A guanosine analog with diverse biological activities Oxanosine Chemical Structure
  44. GC44582 p-Cymene

    4-Cymene, para-Cymene, NSC 4162

     p-Cymene is a monoterpene that is found in a variety of plants, including C. p-Cymene Chemical Structure
  45. GP10036 p53 tumor suppressor fragment

    H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH

    Regulates cell cycle

     p53 tumor suppressor fragment Chemical Structure
  46. GC44531 PACAP (1-27) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt)

    Pituitary Adenylate Cyclase-activating Peptide (1-27)

     Pituitary adenylate cyclase-activating peptide (PACAP) (1-27) is a PACAP receptor agonist with IC50 values of 3, 2, and 5 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. PACAP (1-27) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt) Chemical Structure
  47. GC44533 PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

    Pituitary Adenylate Cyclase-activating Peptide (6-27)

     Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) Chemical Structure
  48. GC44535 PACAP-related Peptide (human) (trifluoroacetate salt)

    Pituitary Adenylate Cyclase-activating Peptide-related Peptide (human), PRP (human)

     PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin, glucagon, glucagon-like peptide-1, GLP-2, and pituitary adenylate cyclase-activating polypeptide. PACAP-related Peptide (human) (trifluoroacetate salt) Chemical Structure
  49. GC14676 Pacritinib (SB1518)

    SB1518

     Pacritinib (SB1518) (SB1518) es un inhibidor potente tanto de JAK2 de tipo salvaje (IC50 = 23 nM) como del mutante JAK2V617F (IC50 = 19 nM). Pacritinib (SB1518) también inhibe FLT3 (IC50=22 nM) y su mutante FLT3D835Y (IC50=6 nM). Pacritinib (SB1518) Chemical Structure
  50. GC49024 Palmitic Acid MaxSpec® Standard

    C16:0, Cetylic Acid, NSC 5030

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid MaxSpec® Standard Chemical Structure
  51. GC49023 Palmitic Acid-d9 MaxSpec® Standard

    C16:0-d9, Cetylic Acid-d9

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid-d9 MaxSpec® Standard Chemical Structure
  52. GC49422 PAR2 (1-6) amide (human) (trifluoroacetate salt)

    SLIGKV-NH2

     A peptide agonist of PAR2 PAR2 (1-6) amide (human) (trifluoroacetate salt) Chemical Structure
  53. GC45541 PAR3 (1-6) amide (human) (trifluoroacetate salt)

    Proteinase-Activated Receptor 3, TFRGAP-NH2

       PAR3 (1-6) amide (human) (trifluoroacetate salt) Chemical Structure
  54. GC47925 Pasireotide (aspartate) (trifluoroacetate salt)

    SOM230

     A somatostatin receptor agonist Pasireotide (aspartate) (trifluoroacetate salt) Chemical Structure
  55. GC48493 PCI 45227

    Dihydrodiol Ibrutinib

     PCI 45227 (PCI-45227) es un metabolito dihidrodiolactivo de ibrutinib, tiene una actividad inhibitoria hacia BTK aproximadamente 15 veces menor que la de ibrutinib. PCI 45227 Chemical Structure
  56. GC91595 PDIC-NC PDIC-NC is an activator of stimulator of interferon genes (STING) and an anticancer agent. PDIC-NC Chemical Structure
  57. GC91688 PDIC-NN PDIC-NN is an intermediate in the synthesis of PDIC-NS , an activator of stimulator of interferon genes (STING) with anticancer activity. PDIC-NN Chemical Structure
  58. GC91820 PDIC-NS PDIC-NS is an activator of stimulator of interferon genes (STING). PDIC-NS Chemical Structure
  59. GC52107 PEG diamine

    PEG-bis-amine, Polyoxyethylene-bis-amine

     A PEGylated building block PEG diamine Chemical Structure
  60. GC44590 Pellitorine La pellitorina es un compuesto aislado de las raÍces de Piper nigrum. La pellitorina muestra fuertes actividades citotÓxicas contra las lÍneas celulares HL60 y MCT-7. La pellitorina tiene potencial para la investigaciÓn de enfermedades cancerosas. Pellitorine Chemical Structure
  61. GC44591 Pemetrexed (sodium salt hydrate) Pemetrexed (hidrato de sal de sodio) es un nuevo antifolato, los valores Ki del pentaglutamato de LY231514 son 1,3, 7,2 y 65 nM para inhibir la timidilato sintasa (TS), la dihidrofolato reductasa (DHFR) y la glicinamida ribonucleÓtido formiltransferasa (GARFT), respectivamente . Pemetrexed (sodium salt hydrate) Chemical Structure
  62. GC46198 Penicinoline An alkaloid Penicinoline Chemical Structure
  63. GC26431 Pentacosafluorotridecanoic Acid

    PFTrDA

    Perfluorotridecanoic Acid (Perfluorinated Compound (PFC)) is a perfluorinated alkyl acid (PFAA) and a possible organic pollutant

     Pentacosafluorotridecanoic Acid Chemical Structure
  64. GC45814 Pentanoic Acid-d9

    C5:0-d9, Valeric Acid-d9

     An internal standard for the quantification of pentanoic acid Pentanoic Acid-d9 Chemical Structure
  65. GC49530 Phenformin-d5 (hydrochloride)

    Phenethylbiguanide-d5 hydrochloride

     An internal standard for the quantification of phenformin Phenformin-d5 (hydrochloride) Chemical Structure
  66. GC47948 Phenoxazine

    NSC 72990

     A heterocyclic building block Phenoxazine Chemical Structure
  67. GC46202 Phenoxybenzamine-d5 (hydrochloride) Fenoxibenzamina-d5 (clorhidrato) es el clorhidrato de fenoxibenzamina marcado con deuterio. Phenoxybenzamine-d5 (hydrochloride) Chemical Structure
  68. GC44629 Pheophorbide a

    2Deacetyl2vinylbacteriopheophorbide

     Pheophorbide a is a product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer. Pheophorbide a Chemical Structure
  69. GC44637 PHPS1

    PTP Inhibitor V

     PHPS1 es un inhibidor de Shp2 potente y selectivo con Kis de 0,73, 5,8, 10,7, 5,8 y 0,47 μM para Shp2, Shp2-R362K, Shp1, PTP1B y PTP1B-Q, respectivamente. PHPS1 Chemical Structure
  70. GC49441 Plerixafor (hydrochloride hydrate)

    AMD 3100, JM 3100, SID 791

     An antagonist of CXCR4 Plerixafor (hydrochloride hydrate) Chemical Structure
  71. GC49148 Plitidepsin

    Aplidin, Dehydrodidemnin B

     La plitidepsina (Aplidine) es un potente agente anticancerÍgeno que se dirige a eEF1A2 (KD=80nM). Plitidepsin Chemical Structure
  72. GC18271 Polmacoxib El polmacoxib (CG100649) es un fÁrmaco antiinflamatorio no esteroideo (AINE) activo por vÍa oral, el primero de su clase, que es un inhibidor dual de la COX-2 (IC50 de alrededor de 0,1 μg/ml) y la anhidrasa carbÓnica. Polmacoxib inhibe el adenoma colorrectal y el crecimiento tumoral en modelos de ratÓn. Polmacoxib Chemical Structure
  73. GC46207 Polygodial pyridazine A derivative of polygodial Polygodial pyridazine Chemical Structure
  74. GC47965 Pomalidomide-d5 Pomalidomida-d5 es pomalidomida marcada con deuterio. La pomalidomida, el agente inmunomodulador de tercera generaciÓn, actÚa como un pegamento molecular. La pomalidomida interactÚa con la ligasa E3 cereblon e induce la degradaciÓn de los factores de transcripciÓn Ikaros esenciales. Pomalidomide-d5 Chemical Structure
  75. GC91966 Ppc-1 Ppc-1 es un ácido quinolinecarboxílico prenilado originalmente aislado de P. pseudo-candidum que tiene diversas actividades biológicas. Ppc-1 Chemical Structure
  76. GC48501 Preterramide C La preterramida C es un metabolito fÚngico. Preterramide C Chemical Structure
  77. GC74594 Pritumumab Pritumumab es un IgG1kappa mAb humano natural originalmente aislado de un ganglio linfádrenregional de un paciente con carcinoma cervical. Pritumumab Chemical Structure
  78. GC41572 PRLX-93936

    PRLX-93936 is an analog of erastin that has antitumor activity.

     PRLX-93936 Chemical Structure
  79. GP10072 Pro-Adrenomedullin (153-185), human

    H2N-Ser-Leu-Pro-Glu-Ala-Gly-Pro-Gly-Arg-Thr-Leu-Val-Ser-Ser-Lys-Pro-Gln-Ala-His-Gly-Ala-Pro-Ala-Pro-Pro-Ser-Gly-Ser-Ala-Pro-His-Phe-Leu-OH

    Vasodilator

     Pro-Adrenomedullin (153-185), human Chemical Structure
  80. GC91919 Pro-GA

    Pro-glutaryl Alanine

     Pro-GA es una forma profarmacológica de n-glutaril-l-alanina y un inhibide la − -glutamilciclotransferasa (GGCT), una enzima involucrada en el metabolismo del glutatión. Pro-GA Chemical Structure
  81. GC18310 Prostaglandin A1

    PGA1

    Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.

     Prostaglandin A1 Chemical Structure
  82. GP10002 prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]

    H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH

    Transcriptional repressor

     prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] Chemical Structure
  83. GC48406 PSI (trifluoroacetate salt)

    Proteasome Inhibitor I, Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde, Z-Ile-Glu(OtBu)-Ala-Leu-CHO

     A proteasome inhibitor PSI (trifluoroacetate salt) Chemical Structure
  84. GC49914 Pt(II)-NHC Complex 2C

    Platinum(II)-N-Heterocyclic Carbene Complex 2C

     An inducer of immunogenic cancer cell death Pt(II)-NHC Complex 2C Chemical Structure
  85. GC60311 PTUPB PTUPB es un novedoso inhibidor dual de COX-2 y sEH con valores de IC50 de 1.26 nM y 0.9 μM, respectivamente. PTUPB Chemical Structure
  86. GC52484 Purified Ganglioside Mixture (bovine) (ammonium salt) A mixture of purified bovine gangliosides Purified Ganglioside Mixture (bovine) (ammonium salt) Chemical Structure
  87. GC15594 PX 12

    IV-2

     An irreversible inhibitor of thioredoxin-1 PX 12 Chemical Structure
  88. GC40568 Pyrocoll Pyrocoll is a bacterial metabolite originally isolated from Streptomyces. Pyrocoll Chemical Structure
  89. GC44791 Pyrrolidine Linoleamide Linoleic acid is an essential fatty acid and one of the most abundant polyunsaturated fatty acids in the western diet. Pyrrolidine Linoleamide Chemical Structure
  90. GC44792 Pyrrolidine Ricinoleamide Ricinoleic acid is a naturally occurring 12-hydroxy fatty acid. Pyrrolidine Ricinoleamide Chemical Structure
  91. GP10032 Rac GTPase fragment

    H2N-Val-Phe-Asp-Glu-Ala-Ile-Arg-Ala-Val-OH

    Fragment of small signaling G proteins

     Rac GTPase fragment Chemical Structure
  92. GC10906 RBC8 RBC8 es un nuevo inhibidor de molécula pequeÑa de Ral GTPasa; tiene IC50 de 3,5 μM en células H2122 y 3,4 μM en células H358. RBC8 Chemical Structure
  93. GC65288 Resibufagin La resibufagina es una especie de bufadienolida aislada del veneno de Bufo bufo gargarizans, tiene actividades antitumorales. Resibufagin Chemical Structure
  94. GC18955 Reveromycin C Reveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C. Reveromycin C Chemical Structure
  95. GC52067 Rhamnopterin A derivative of biopterin Rhamnopterin Chemical Structure
  96. GC45798 Rhein-13C4

    Rheic Acid-13C4

    An internal standard for the quantification of rhein

     Rhein-13C4 Chemical Structure
  97. GC91920 Rhein-13C6

    Rheic Acid-13C6

     Rhein-13C6 está destinado a usarse como norma interna para la cuantificación de Rhein por GC- o LC-MS. Rhein-13C6 Chemical Structure
  98. GC46214 Roccellic Acid

    (+)-Roccellic Acid, NSC 249985

     A lichen secondary metabolite Roccellic Acid Chemical Structure
  99. GC49190 Roxadustat-d5 Roxadustat-d5 es Roxadustat etiquetado con deuterio. Roxadustat es un inhibidor de la prolil-hidroxilasa del factor inducible por hipoxia oral (HIF-PHI) que promueve la eritropoyesis mediante el aumento de la eritropoyetina endÓgena, la mejora de la regulaciÓn del hierro y la reducciÓn de la hepcidina. Roxadustat-d5 Chemical Structure
  100. GC90611 RTDLDSLRTYTL (trifluoroacetate salt)

    Un ligando del integrina αVβ6.

     RTDLDSLRTYTL (trifluoroacetate salt) Chemical Structure
  101. GC48693 Rubiginone D2 A polyketide with antibacterial and anticancer activities Rubiginone D2 Chemical Structure

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