AP-1

Activator protein 1 (AP-1) is a transcription factor that consist of Jun, Fos, ATF and JDP proteins. It is regulated by cytokines, growth factors, stress signals and infections etc. It is involved in cellular proliferation, transformation and apoptosis.

Products for AP-1

Cat.No. Nombre del producto Información
GC74247 (+)-Glaucarubinone (+)-Glaucarubinone es un potente inhibide la AP-1 activator protein-1 con un valor de EC50 de 0.13 µM.
GC74013 FOSL1 degrader 1 FOSL1 degrader 1 (4) es un T-5224-PROTAC, que degrada en forma potencial FOSL1 (AP-1) para suprimir la expresión génica de la proctidad del cáncer en HNSCC.
GC71181 Glucocorticoid receptor modulator 1 Glucocorticoid receptor modulator 1 is a highly potent and orally active non-steroidal selective glucocorticoid receptor modulator with an IC50 value of 9 nM and 130 nM for NF-κB and AP-1, respectively.
GC72757 SPC 839 SPC 839 (compuesto 10) es un inhibidor activo oral de la activación transcripcional mediada por AP-1 y NF-kB con IC50 de 0,008 μM.
GC12810 SR 11302 An inhibitor of retinoid-induced AP-1 signaling
GC72363 Timolumab Timolumab (BTT1023), un anticuerpo monoclonal recombintotalmente humano que se une específicamente al VAP-1.