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Inicio >> Signaling Pathways >> Membrane Transporter/Ion Channel >> GTPase

GTPase

Products for  GTPase

  1. Cat.No. Nombre del producto Información
  2. GC40452 15(S)-HETE MaxSpec® Standard 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE MaxSpec® Standard Chemical Structure
  3. GC11483 8-CPT-2Me-cAMP, sodium salt

    8-CPT-2MecAMP, 8-pCPTcAMP, 8-pCPT-2′-OMe-cAMP

     La sal sÓdica de 8-CPT-2Me-cAMP es un activador selectivo de proteÍnas de intercambio activadas por cAMP (Epac), los factores de intercambio de nucleÓtidos de guanina (GEF) sensibles a cAMP para las pequeÑas GTPasas Rap1 y Rap2. 8-CPT-2Me-cAMP, sodium salt Chemical Structure
  4. GC18426 8-Nitroguanine 8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents. 8-Nitroguanine Chemical Structure
  5. GC16199 8-pCPT-2-O-Me-cAMP-AM Epac activator 8-pCPT-2-O-Me-cAMP-AM Chemical Structure
  6. GC39810 CID44216842

    Cdc42-IN-1

     CID44216842 (Cdc42-IN-1) es un potente inhibidor de plomo de uniÓn de nucleÓtido de guanina selectivo de Cdc42. Las CE50 para el mutante Cdc42 WT y Cdc42Q61L son 1,0 y 1,2 μM en el ensayo de uniÓn a GTP, respectivamente. Las CE50 para el mutante Cdc42 WT y Cdc42Q61L son 0,3 y 0,5 μM en el ensayo de uniÓn de GDP, respectivamente. Uso como sonda molecular. CID44216842 Chemical Structure
  7. GC43306 Compound C108 Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation. Compound C108 Chemical Structure
  8. GC91590 DTPD-Q

    2,5-Bis(o-tolylamino)cyclohexa-2,5-diene-1,4-dione,DTPD-quinone

     DTPD-Q is an oxidized derivative of the antioxidant and methylphenyl substituted p-phenylenediamine DTPD. DTPD-Q Chemical Structure
  9. GC14179 Dynole 34-2 Dynole 34-2 es un inhibidor de la dinamin GTPasa (IC50s = 6,9 y 14,2 μM para la actividad de dynamin1 y dynamin2 GTPasa, respectivamente) con efecto antimitÓtico. Dynole 34-2 induce la apoptosis, como lo revelan las ampollas celulares, la fragmentaciÓn del ADN y la escisiÓn de PARP. Dynole 34-2 también inhibe potentemente la endocitosis mediada por receptores (RME). Dynole 34-2 Chemical Structure
  10. GC20107 Fendiline hydrochloride

    Fendiline hydrochloride is a nonselective calcium channel blocker.

     Fendiline hydrochloride Chemical Structure
  11. GC49089 FR900359

    UBO-QIC

     FR900359 is an inhibitor of G proteins Gαq, Gα11, and Gα14 with IC50 values of 13.18, 10.47, and 10nM, respectively and is isolated from the leaves of the ornamental plant Ardisia crenata FR900359 Chemical Structure
  12. GC18260 FTase Inhibitor I

    Farnesyltransferase Inhibitor I

    El inhibidor de FTasa I es un potente inhibidor de la farnesiltransferasa (FTasa; IC50 = 21 nM) que es más de 30 veces selectivo para la FTasa sobre la geranilgeranil transferasa (GGTase; IC50 = 790 nM).

     FTase Inhibitor I Chemical Structure
  13. GC52503 FTase Inhibitor II (trifluoroacetate salt)

    Farnesyltransferase Inhibitor II, FTI-II

     A potent, selective inhibitor of farnesyltransferase FTase Inhibitor II (trifluoroacetate salt) Chemical Structure
  14. GC90919 Guanosine 5'-[γ-thio]triphosphate (sodium salt)

    Un análogo resistente a la hidrólisis de GTP.

     Guanosine 5'-[γ-thio]triphosphate (sodium salt) Chemical Structure
  15. GC49033 Guanosine 5’-diphosphate (sodium salt hydrate)

    GDP

     A purine nucleotide Guanosine 5’-diphosphate (sodium salt hydrate) Chemical Structure
  16. GC49703 Guanosine 5’-[γ-thio]triphosphate (lithium salt)

    GTPγS, Guanosine 5'-O-(3-thio)triphosphate, Guanosine 5'-trihydrogen diphosphate monoanhydride Phosphorothioic Acid

     A hydrolysis-resistant analog of GTP Guanosine 5’-[γ-thio]triphosphate (lithium salt) Chemical Structure
  17. GC17852 Gue 1654 Gue 1654 es un modulador de OXE-R. Gue 1654 Chemical Structure
  18. GC15722 HJC 0350 HJC 0350 es un antagonista de EPAC2 potente y específico con una IC50 de 0,3 µM. HJC 0350 Chemical Structure
  19. GC47477 JKE-1674 JKE-1674 es un inhibidor de la glutatiÓn peroxidasa 4 (GPX4) activo por vÍa oral y un metabolito activo del inhibidor de GPX4 ML-210. JKE-1674, un anÁlogo de ML-210 en el que el anillo de nitroisoxazol se reemplaza con una α-nitroketoxima. JKE-1674 puede convertirse en un Óxido de nitrilo JKE-1777. JKE-1674 mata las células LOX-IMVI de una manera que es equipotente a ML-210 y es completamente rescatada por inhibidores de ferroptosis. JKE-1674 Chemical Structure
  20. GC47478 JKE-1716 JKE-1716 es un inhibidor de GPX4 potente y selectivo que contiene Ácido nÍtrico. JKE-1716 Chemical Structure
  21. GC44020 L-681,217 L-681,217 is an antibiotic originally isolated from S. L-681,217 Chemical Structure
  22. GC47601 Mastoparan (trifluoroacetate salt) A neuropeptide with diverse biological activities Mastoparan (trifluoroacetate salt) Chemical Structure
  23. GC52250 Mevalonate (lithium salt)

    Mevalonic Acid, MVA, Pentanoic Acid

     An intermediate in the mevalonate pathway Mevalonate (lithium salt) Chemical Structure
  24. GC13243 MitMAB

    TTABr, TTAB

     MitMAB, un bloque de construcciÓn orgÁnico, es un tensioactivo catiÓnico con estructura asimétrica. MitMAB Chemical Structure
  25. GC18445 N-Deacetylcolchicine

    NSC 201400

     An inhibitor of microtubule polymerization N-Deacetylcolchicine Chemical Structure
  26. GC11880 OctMAB Dynamin inhibitor OctMAB Chemical Structure
  27. GC44506 Oligomycin D

    26-Demethyloligomycin A

    Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport.

     Oligomycin D Chemical Structure
  28. GC44763 PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt)

    DOPI4,5P2, Phosphatidylinositol4,5bisphosphate C8

     The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids. PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt) Chemical Structure
  29. GC48094 Spiro-Oxanthromicin A A polyketide Spiro-Oxanthromicin A Chemical Structure
  30. GC91153 Sulfonadyn-47

    Un inhibidor de la dinamina.

     Sulfonadyn-47 Chemical Structure

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