Metabolism
- Sterol Biosynthesis(26)
- PPAR(216)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(8)
- Aminopeptidase(10)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(63)
- CETP(13)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(26)
- Dehydrogenase(139)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(14)
- Enolase(11)
- FAAH(40)
- Factor Xa(49)
- Ferroptosis(200)
- Folate Analogue(3)
- Glucokinase(17)
- HLE(1)
- HMG-CoA Reductase(39)
- HSP(77)
- IDO(52)
- KRAS-PDEδ(4)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(146)
- PDE(254)
- Phospholipase(117)
- Procollagen C Proteinase(2)
- Saccharometabolism(1)
- SCD(19)
- SGLT(31)
- TPH(6)
- Transferase(183)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(98)
- Pyruvate kinase(9)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
Products for Metabolism
- Cat.No. Nombre del producto Información
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GC66197
α-?Terpinyl acetate
α-El acetato de terpinilo es un éster de monoterpeno aislado del aceite esencial de Laurus nobilis L. α-El acetato de terpinilo es un sustrato competitivo de P450 2B6 que se une al sitio activo de P450 2B6 con un valor Kd de 5,4μM.
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GC11123
α-CEHC
A major metabolite of δ-tocopherol
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GC48276
α-Cyclodextrin (hydrate)
A cyclic hexasaccharide
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GC48278
α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
A bis-phosphorylated derivative of α-D-glucose
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GC48279
α-D-Glucose-1-phosphate (sodium salt hydrate)
An intermediate in glycogen metabolism
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GC52253
α-Enolase (1-19)-biotin Peptide
A biotinylated α-enolase peptide
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GC45208
α-hydroxy Metoprolol
α-hydroxy Metoprolol is an active metabolite of the β1-adrenergic receptor blocker metoprolol.
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GC45210
α-Linolenic Acid (sodium salt)
α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables.
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GC48283
α-Linolenic Acid-d14
An internal standard for the quantification of αLinolenic acid
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GC45602
α-Linolenic Acid-d5 MaxSpec• Standard
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GC49008
α-Muricholic Acid-d4
An internal standard for the quantification of α-muricholic acid
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GC40480
α-Phenyl-α-(2-pyridyl)acetonitrile
α-Phenyl-α-(2-pyridyl)thioacetamide, also known as antigastrin and SC-15396, is an inhibitor of gastric acid secretion.
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GC45232
β-D-Glucosamine Pentaacetate
β-D-Glucosamine pentaacetate is an N-acetylglucosamine derivative that has been shown to promote hyaluronic acid production.
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GC49769
β-Glucogallin
A plant metabolite and an aldose reductase 2 inhibitor
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GC49890
β-Glycerophosphate-d5 (sodium salt hydrate)
An internal standard for the quantification of β-glycerophosphate
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GC49647
β-Hyodeoxycholic Acid (hydrate)
A 3β epimer of hyodeoxycholic acid
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GC49007
β-Muricholic Acid-d4
An internal standard for the quantification of β-muricholic acid
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GC41502
β-Myrcene
β-Myrcene (β-ޚ-Myrcene), un compuesto volátil aromático, suprime la actividad de NF-κB inducida por TNFα.
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GC40551
γ-CEHC
The major tocopherol obtained from natural dietary sources is γ-tocopherol, whereas α-tocopherol is the form of Vitamin E typically obtained from synthetic supplements.
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GC52400
γ-Glu-Ala (trifluoroacetate salt)
A dipeptide
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GC52404
γ-Glu-Phe (trifluoroacetate salt)
A dipeptide with metabolism-altering activity
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GC45239
δ4-Abiraterone
δ4-Abiraterona es un metabolito principal de abiraterona. δ4-Abiraterona es un inhibidor de CYP17A1, 3b-hidroxiesteroide deshidrogenasa (3βHSD) y esteroide-5a-reductasa (SRD5A) y también un antagonista del receptor de andrÓgenos.
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GC15975
α-Estradiol
α-El estradiol es un estrÓgeno débil y un 5&7#945;-inhibidor de la reductasa que se usa como medicamento tÓpico en el tratamiento de la alopecia androgénica.
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GC49009
ω-Muricholic Acid-d4
An internal standard for the quantification of ω-MCA
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GC49296
τ-Fluvalinate
A pyrethroid acaricide
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GC46314
(±)-β-Hydroxybutyrate-d4 (sodium salt)
An internal standard for the quantification of (±)βhydroxybutyrate
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GC52010
(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid
An oxylipin gut microbiota metabolite
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GC52013
(±)-10-hydroxy-12(Z)-Octadecenoic Acid
An oxylipin and metabolite of linoleic acid
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GC52421
(±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5
An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid
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GC41661
(±)-4-hydroxy Propranolol β-D-Glucuronide
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.
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GC46284
(±)-Cotinine-d3
An internal standard for the quantification of cotinine
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GC41671
(±)-Equol 4'-sulfate (sodium salt)
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
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GC41315
(±)-Ketoprofen Glucuronide
(±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen.
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GC40954
(±)-N-3-Benzylnirvanol
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (-)-N-3-benzylnirvanol.
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GC49875
(±)-N-desmethyl Venlafaxine (hydrochloride)
A minor active metabolite of venlafaxine
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GC39271
(±)-Naringenin
(±)-naringenina es un flavonoide natural.
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GC45618
(±)-trans-GK563
A GVIA iPLA2 inhibitor
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GC40802
(±)12(13)-DiHOME
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.
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GC40270
(±)5(6)-DiHET
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
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GC40282
(+)-5-trans Cloprostenol
Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses.
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GC45260
(+)-Cloprostenol isopropyl ester
(+) - éster isopropÍlico de cloprostenol, una prostaglandina F2α anÁlogos, es el intermedio de (+)-cloprostenol.
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GC45262
(+)-Cloprostenol methyl ester
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α).
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GC45264
(+)-Geodin
(+) - Geodin, un metabolito fúngico, muestra actividad antibacteriana.
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GC12404
(+)-Ketoconazole
(+)-ketoconazol ((+)-R 41400) es un agente antifÚngico de imidazol, un inhibidor de CYP3A4.
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GC30424
(-)-Cephaeline dihydrochloride (NSC 32944)
El diclorhidrato de (-)-cefaelina (NSC 32944) es un inhibidor selectivo de CYP2D6 con un IC50 de 121 μM.
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GC18343
(-)-CP 55,940
(-)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively.
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GC14049
(-)-Epigallocatechin gallate (EGCG)
Un fenol con diversas actividades biológicas.
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GC45248
(-)-FINO2
(-)-FINO2 es un potente inductor de ferroptosis. (-)-FINO2 inhibe la actividad de GPX4. (-)-FINO2 es un oxidante estable que oxida el hierro ferroso y es estable a diferentes niveles de pH. (-)-FINO2 provoca una peroxidaciÓn lipÍdica generalizada.
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GC14520
(-)-p-Bromotetramisole Oxalate
Inhibidor de la ALP, potente y no específico.
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GC45252
(-)-Sitagliptin Carbamoyl Glucuronide
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
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GC18622
(2'S)-Nicotine-1-oxide
(2'S)-Nicotine-1-oxide is a metabolite of nicotine .
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GC41691
(2R)-Glycerol-O-β-D-galactopyranoside
(2R)-Glicerol-O-β-D-galactopiranÓsido (3-O-β-D-Galactopiranosil-sn-glicerol) es un buen sustrato para los tres componentes del operÓn lac, i.
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GC49690
(3R,5R)-Rosuvastatin (calcium salt)
A potential impurity found in bulk preparations of rosuvastatin
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GC41694
(3S)-hydroxy Quinidine
(3S)-hydroxy Quinidine is an active quinidine metabolite.
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GC60396
(3S,5R)-Fluvastatin sodium
(3S,5R)-fluvastatina sÓdica ((3S,5R)-XU 62-320) es el enantiÓmero (3S,5R)de fluvastatina.
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GC68317
(3S,5R)-Fluvastatin-d6 sodium
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GC13751
(3S,5S)-Atorvastatin (sodium salt)
negetive control of Atorvastatin, HMG-CoA reductase inhibitor
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GC46333
(4′-Hydroxy)phenoxybenzoic Acid
A pyrethroid insecticide metabolite
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GC48508
(4-Carboxybutyl-d4)triphenylphosphonium (bromide)
An internal standard for the quantification of (4-carboxybutyl)triphenylphosphonium
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GC41695
(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)
(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.
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GC41088
(6S)-Tetrahydrofolic Acid
(6S)-Tetrahydrofolic acid is a diastereomer of tetrahydrofolic acid, a reduced form of folic acid that serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.
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GC34980
(E)-Ferulic acid
El Ácido (E)-ferÚlico es un isÓmero del Ácido ferÚlico, que es un compuesto aromÁtico, abundante en las paredes celulares de las plantas. El Ácido (E)-ferÚlico provoca la fosforilaciÓn de la β-catenina, lo que da como resultado la degradaciÓn proteasomal de la β-catenina y aumenta la expresiÓn del factor proapoptÓtico Bax y disminuye la expresiÓn del factor prosupervivencia survivina. El Ácido (E)-ferÚlico muestra una potente capacidad para eliminar las especies reactivas de oxÍgeno (ROS) e inhibe la peroxidaciÓn lipÍdica. El Ácido (E)-ferÚlico ejerce efectos antiproliferaciÓn y antimigraciÓn en la lÍnea celular de cÁncer de pulmÓn humano H1299.
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GC40286
(E,Z)-2-propyl-2-Pentenoic Acid
(E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity.
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GC49189
(E/Z)-4-hydroxy Tamoxifen-d5
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
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GA11210
(H-Cys-OH)2
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GC34984
(R)-(-)-Rolipram
(R)-(-)-Rolipram es el enantiÓmero R de Rolipram.
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GC25001
(R)-Avanafil
R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM.
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GC40678
(R)-Bromoenol lactone
La (R)-bromoenol lactona ((R)-BEL) es un inhibidor irreversible, quiral y basado en un mecanismo de la fosfolipasa γ independiente del calcio (iPLA2γ).
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GC52290
(R)-HTS-3
An inhibitor of LPCAT3
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GC67864
(R)-Irsenontrine
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GC41722
(R,S)-Carvedilol Glucuronide
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.
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GC61548
(Rac)-5-Keto Fluvastatin
(Rac)-5-Keto Fluvastatin (3-Hydroxy-5-Keto Fluvastatin) es una impureza de Fluvastatin (XU 62320).
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GC62743
(Rac)-EC5026
(Rac)-EC5026 ((Rac)-BPN-19186) es un potente inhibidor de piperidina de la epÓxido hidrolasa soluble (sEH) extraÍdo de la patente WO2019156991A1, pÁgina 39, tiene una Ki de 0,06 nM.
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GC69796
(Rac)-Etavopivat
(Rac)-Etavopivat ((Rac)-FT-4202) es un isómero de Etavopivat. Etavopivat es un activador oralmente activo de la piruvato quinasa-R (PKR) en los glóbulos rojos, que se puede utilizar para investigar la enfermedad de células falciformes y otras enfermedades de hemoglobina.
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GC61750
(Rac)-Indoximod
(Rac)-indoximod (1-metil-DL-triptÓfano) es un inhibidor de la indolamina 2,3-dioxigenasa (IDO).
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GC46347
(S)-(+)-Methoprene
El (S)-metopreno es un análogo de la hormona juvenil que impide que el insecto cambie de pupa a adulto y se usa como insecticida.
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GC40679
(S)-Bromoenol lactone
La (S)-bromoenol lactona ((S)-BEL) es un inhibidor irreversible, quiral, basado en un mecanismo de la fosfolipasa A2β independiente del calcio (iPLA2β) que inhibe la liberaciÓn de araquidonato inducida por vasopresina a partir de mÚsculo liso aÓrtico de rata en cultivo (A10) células con una IC50 de 2 μM.
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GC50321
(S)-C33
(S)-C33 es un inhibidor potente y selectivo de la PDE9 (fosfodiesterasa-9), con una IC50 de 11 nM.
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GC48719
(S)-Canadine
La (S)-canadina es un alcaloide e intermedio en la biosÍntesis de la berberina con actividad insecticida.
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GC46352
(S)-DO271
An inactive control for DO264
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GC49520
(S)-Equol
(S)-Equol es un ligando de alta afinidad por el receptor de estrógeno β con una Ki de 0,73 nM.
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GC60417
(S)-Indoximod
El (S)-indoximod (1-metil-L-triptÓfano) es un inhibidor de la indolamina 2,3-dioxigenasa (IDO). (S)-Indoximod se puede utilizar para la investigaciÓn del cÁncer.
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GC69891
(S)-Indoximod-d3
(S)-Indoximod-d3 es la forma deuterada de (S)-Indoximod. (S)-Indoximod (1-Metil-L-triptófano) es un inhibidor de la enzima indolamina-2,3-dioxigenasa (IDO). (S)-Indoximod se utiliza en investigaciones sobre el cáncer.
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GC40145
(S)-Laudanosine
(S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium.
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GC14486
(S)-Mephenytoin
(S)-Mephenytoin ((+)-Mephenytoin) es un agente anticonvulsivo.
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GC49179
(S)-O-Desmethyl Naproxen
A metabolite of (S)-naproxen
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GC18596
(±)-2-propyl-4-Pentenoic Acid
El Ácido (±)-2-propil-4-pentenoico (4-en-VPA) es un metabolito tÓxico principal del Ácido valproico.
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GC49034
1(R)-(Trifluoromethyl)oleyl alcohol
An oleic acid analog
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GC46365
1,1'-(Azodicarbonyl)dipiperidine
A Mitsunobu reagent
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GC41762
1,2,3,5-Tetra-O-acetyl-D-xylofuranose
1,2,3,5-Tetra-O-acetil-D-xilofuranosa es la materia prima para la sÍntesis de nucleÓtidos.
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GC46040
1,2,3-Trielaidoyl-rac-glycerol
A triacylglycerol
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GC45698
1,2,3-Triheptanoyl-rac-glycerol
El 1,2,3-triheptanoil-rac-glicerol (propano-1,2,3-triiltriheptanoato) es un triglicérido de cadena media (MCT) sintético que consta de tres Ácidos grasos de cadena impar de 7 carbonos (heptanoato) en un glicerol columna vertebral.
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GC45285
1,2,3-Trihexanoyl-rac-glycerol
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GC45956
1,2,3-Trinonanoyl-rac-glycerol
A triacylglycerol
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GC46009
1,2,3-Trioctanoyl-rac-glycerol-13C3
An internal standard for the quantification of 1,2,3-trioctanoyl glycerol-13C3
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GC46373
1,2,3-Triundecanoyl Glycerol
A triacylglycerol
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GC41782
1,2-bis(heptanoylthio) Glycerophosphocholine
Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).
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GC40236
1,2-Dilinoleoyl-sn-glycerol
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions.
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GC41808
1,2-Dioctanoyl PC
Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane.
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GC41837
1,3,7-Trimethyluric Acid
El Ácido 1,3,7-trimetilÚrico es el metabolito de la cafeÍna. La proporciÓn metabÓlica de Ácido 1,3,7-trimetilÚrico a cafeÍna se puede evaluar como biomarcador para describir la variabilidad en la actividad de CYP3A en una cohorte.