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Inicio >> Signaling Pathways >> Others >> Menin-MLL

Menin-MLL

Menin-MLL interaction is a drug target for leukemia treatment. Menin is a multiple endocrine neoplasia (MEN1) products which interacts with MLL (mixed lineage leukemia) in a histone methyltransferase complex.

Products for  Menin-MLL

  1. Cat.No. Nombre del producto Información
  2. GC11837 MI-136 MI-136 es un inhibidor de la interacciÓn proteÍna-proteÍna (PPI) menina-MLL, con una IC50 de 31 nM y una Kd de 23,6 nM. MI-136 muestra que bloquea la seÑalizaciÓn de AR y tiene el potencial para el estudio en tumores resistentes a la castraciÓn. MI-136 Chemical Structure
  3. GC11418 MI-2

    Menin-MLL inhibitor 2;Thieno[2,3-d]pyrimidine, 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propyl-

     An inhibitor of menin-MLL fusion protein interactions MI-2 Chemical Structure
  4. GC10388 MI-2 (hydrochloride) menin-MLL interaction inhibitor MI-2 (hydrochloride) Chemical Structure
  5. GC12199 MI-3

    Menin-MLL inhibitor 3;Thieno[2,3-d]pyrimidine, 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-(1-methylethyl)-

     An inhibitor of menin-MLL fusion protein interactions MI-3 Chemical Structure
  6. GC12173 MI-nc (hydrochloride) weak inhibitor of menin-MLL interaction MI-nc (hydrochloride) Chemical Structure

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