Steffimycin B (Synonyms: NSC 204855, U 40615) |
| Catalog No.GC40859 |
Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces.
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Cas No.: 54526-94-2
Sample solution is provided at 25 µL, 10mM.
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Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine. Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC50s = 3.5, 6.75, 3.28, and 10.5 μM, respectively). It is active against M. tuberculosis (MIC = 5.2 nM), B. cereus (MIC = 1.56 μg/ml), and P. falciparum (IC50 = 2.19 μM).
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
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