T.cruzi-IN-1 |
| Catalog No.GC61950 |
T.cruzi-IN-1 is a potent?Trypanosoma cruzi?inhibitor with an?IC50?of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1350920-22-7
Sample solution is provided at 25 µL, 10mM.
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T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease[1].
T.cruzi-IN-1 inhibits Trypanosoma cruzi replication and has an IC50 of 61.6 µM for toxicity[1].
References:
[1]. Germain AR, et al. Identification of small-molecule inhibitors of Trypansoma cruzi replication. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7197-200.
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
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