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TAPI 0

Catalog No.GC50189

ADAM-17 (TACE) and MMP inhibitor

Products are for research use only. Not for human use. We do not sell to patients.

TAPI 0 Chemical Structure

Cas No.: 163958-73-4

Size Price Stock Qty
1 mg
$447.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.

Balakrishnan et al (2006) Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium. J.Biol.Chem. 281 16691 PMID:16565079 |Rzeniewicz et al (2015) L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro. Proc.Natl.Acad.Sci.USA. 112 E1461 PMID:25775539

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Average Rating: 5 ★★★★★ (Based on Reviews and 17 reference(s) in Google Scholar.)

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