Target Protein-binding moiety 8 (Synonyms: N-Deshydroxyethyl BMS-354825) |
| Catalog No.GC33350 |
Target Protein-binding moiety 8 (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, Dasatinib is a multi-kinase inhibitor that potently inhibits Bcr-Abl, Src family and platelet-derived growth factor receptor kinases.
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Cas No.: 910297-51-7
Sample solution is provided at 25 µL, 10mM.
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Target Protein-binding moiety 8 is a compound binding to BCR-ABL, and used for inhibiting BCR-ABL activity.
Target Protein-binding moiety 8 (Compound 8) is a compound binding to BCR-ABL, and used for inhibiting BCR-ABL activity.
[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.
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