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TC-A 2317 hydrochloride Catalog No.GC16378

Aurora kinase A inhibitor,potent and selective

Size Price Stock Qty
10mg
$345.00
In stock
50mg
$1,412.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

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Chemical Properties

Cas No. 1245907-03-2 SDF
Chemical Name 6-((3-isocyano-4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyridin-2-yl)amino)-2-methylheptan-2-ol hydrochloride
Canonical SMILES CC(CCCC(C)(C)O)NC1=NC(NC2=NNC(C)=C2)=CC(C)=C1[N+]#[C-].Cl
Formula C19H28N6O.HCl M.Wt 392.93
Solubility <39.29mg/ml in DMSO; <19.65mg/ml in ethanol Storage Store at 4°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

Potent Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50 values > 1000 nM). Exhibits good cell permeability and antitumor activity.