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TC HSD 21 Catalog No.GC13760

17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor

Size Price Stock Qty
10mg
$244.00
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50mg
$1,031.00
Ship Within 7 Days

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & SDS

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Chemical Properties

Cas No. 330203-01-5 SDF
Chemical Name (Z)-5-(3-bromo-4-hydroxybenzylidene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one
Canonical SMILES COC1=CC=C(N(C2=S)C(/C(S2)=C([H])/C3=CC(Br)=C(O)C=C3)=O)C=C1
Formula C17H12BrNO3S2 M.Wt 422.32
Solubility <42.23mg/ml in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors[1].

References:
[1]. Harada K,et al. Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):504-7.