TCN 237 dihydrochloride |
| Catalog No.GC11585 |
TCN 237 dihydrochloride is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 700878-19-9
Sample solution is provided at 25 µL, 10mM.
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NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor.
References:
[1]. McCauley JA, et al. NR2B-selective N-methyl-D-aspartate antagonists: synthesis and evaluation of 5-substituted benzimidazoles. J Med Chem. 2004 Apr 8;47(8):2089-96.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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