Thymoquinone Catalog No.GC18157

A natural phytochemical

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 490-91-5 SDF Download SDF
Synonyms N/A
Chemical Name 2-methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione
Canonical SMILES O=C(C(C(C)C)=C1)C=C(C)C1=O
Formula C10H12O2 M.Wt 164.2
Solubility Soluble in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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The black seeds of Nigella have long been ingested to treat a broad range of diseases, including inflammation and cancer.1 Thymoquinone is a natural phytochemical isolated from the seeds of N. sativa.1 It has anti-inflammatory effects, blocking the synthesis of leukotrienes.2,1 Thymoquinone inhibits the growth of leukemia cells (IC50 = 1.5 μg/ml), inducing apoptosis by down-regulating the expression of Bcl-2 while up-regulating Bax expression.3 In addition to blocking cell proliferation and triggering apoptosis, thymoquinone (15 μM) suppresses STAT3-regulated gene expression and prevents angiogenesis.4,5