Tinostamustine HCl (Synonyms: EDO-S101; EDO-S 101; EDO-S-101; EDO-S101 HCl; EDO-S101 hydrochloride; Tinostamustine hydrochloride ) |
| Catalog No.GC19472 |
An alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1793059-58-1
Sample solution is provided at 25 µL, 10mM.
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Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activity of the compound and/or may help to overcome resistance to other therapeutic agents.
Reference:
[1]. Mehrling T, Chen Y. The Alkylating-HDAC Inhibition Fusion Principle: Taking
[2]. Chemotherapy to the Next Level with the First in Class Molecule EDO-S101.
[3]. Anticancer Agents Med Chem. 2015;16(1):20-8. PubMed PMID: 25980817.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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